ENSG00000134108


Homo sapiens

Features
Gene ID: ENSG00000134108
  
Biological name :ARL8B
  
Synonyms : ADP ribosylation factor like GTPase 8B / ARL8B / Q9NVJ2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: p26.1
Gene start: 5122220
Gene end: 5180912
  
Corresponding Affymetrix probe sets: 217852_s_at (Human Genome U133 Plus 2.0 Array)   222442_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000402996
Ensembl peptide - ENSP00000479202
Ensembl peptide - ENSP00000405196
Ensembl peptide - ENSP00000256496
Ensembl peptide - ENSP00000400831
NCBI entrez gene - 55207     See in Manteia.
OMIM - 616596
RefSeq - NM_018184
RefSeq Peptide - NP_060654
swissprot - Q9NVJ2
swissprot - F8WAW5
swissprot - F2Z344
swissprot - A0A024R2D4
Ensembl - ENSG00000134108
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arl8baENSDARG00000006915Danio rerio
 ARL8BENSGALG00000008314Gallus gallus
 Arl8bENSMUSG00000030105Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ARL8A / Q96BM9 / ADP ribosylation factor like GTPase 8AENSG0000014386292
ARF6 / P62330 / ADP ribosylation factor 6ENSG0000016552733
ARL3 / P36405 / ADP ribosylation factor like GTPase 3ENSG0000013817532
ARF3 / P61204 / ADP ribosylation factor 3ENSG0000013428732
ARF1 / P84077 / ADP ribosylation factor 1ENSG0000014376132
ARL2 / P36404 / ADP ribosylation factor like GTPase 2ENSG0000021346531
ARF4 / P18085 / ADP ribosylation factor 4ENSG0000016837431
ARL11 / Q969Q4 / ADP ribosylation factor like GTPase 11ENSG0000015221330
ARF5 / P84085 / ADP ribosylation factor 5ENSG0000000405930
ARL15 / Q9NXU5 / ADP ribosylation factor like GTPase 15ENSG0000018530528
P36406 / TRIM23 / tripartite motif containing 23ENSG0000011359527
ARL14 / Q8N4G2 / ADP ribosylation factor like GTPase 14ENSG0000017967426
AC073610.3ENSG0000027282225
ARL2-SNX15 / ARL2-SNX15 readthrough (NMD candidate)ENSG0000027300320


Protein motifs (from Interpro)
Interpro ID Name
 IPR005225  Small GTP-binding protein domain
 IPR006689  Small GTPase superfamily, ARF/SAR type
 IPR024156  Small GTPase superfamily, ARF type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007059 chromosome segregation IMP
 biological_processGO:0032418 lysosome localization IMP
 biological_processGO:0051301 cell division IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005765 lysosomal membrane IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030496 midbody IDA
 cellular_componentGO:0031902 late endosome membrane IEA
 cellular_componentGO:0051233 spindle midzone IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IDA
 molecular_functionGO:0019003 GDP binding IDA
 molecular_functionGO:0043014 alpha-tubulin binding IDA
 molecular_functionGO:0048487 beta-tubulin binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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