ENSG00000104722


Homo sapiens

Features
Gene ID: ENSG00000104722
  
Biological name :NEFM
  
Synonyms : NEFM / neurofilament medium / P07197
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: 1
Band: p21.2
Gene start: 24913012
Gene end: 24919098
  
Corresponding Affymetrix probe sets: 205113_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000410137
Ensembl peptide - ENSP00000427872
Ensembl peptide - ENSP00000412295
Ensembl peptide - ENSP00000221166
NCBI entrez gene - 4741     See in Manteia.
OMIM - 162250
RefSeq - NM_005382
RefSeq - NM_001105541
RefSeq Peptide - NP_001099011
RefSeq Peptide - NP_005373
swissprot - P07197
swissprot - E7ESP9
swissprot - E7EMV2
Ensembl - ENSG00000104722
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nefmaENSDARG00000021351Danio rerio
 nefmbENSDARG00000043697Danio rerio
 NEFMENSGALG00000000317Gallus gallus
 NefmENSMUSG00000022054Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NEFH / P12036 / neurofilament heavyENSG0000010028537
INA / Q16352 / internexin neuronal intermediate filament protein alphaENSG0000014879826
NEFL / P07196 / neurofilament lightENSG0000027758626
VIM / P08670 / vimentinENSG0000002602521
PRPH / P41219 / peripherinENSG0000013540621
DES / desmin / P17661ENSG0000017508420
GFAP / P14136 / glial fibrillary acidic proteinENSG0000013109519
LMNA / P02545 / lamin A/CENSG0000016078915
LMNB2 / Q03252 / lamin B2ENSG0000017661915
LMNB1 / P20700 / lamin B1ENSG0000011336814


Protein motifs (from Interpro)
Interpro ID Name
 IPR001664  Intermediate filament protein
 IPR002957  Keratin, type I
 IPR006821  Intermediate filament head, DNA-binding domain
 IPR018039  Intermediate filament protein, conserved site
 IPR027697  Neurofilament medium polypeptide


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0033693 neurofilament bundle assembly TAS
 biological_processGO:0061564 axon development IEA
 cellular_componentGO:0005882 intermediate filament IEA
 cellular_componentGO:0005883 neurofilament IEA
 cellular_componentGO:0030424 axon TAS
 cellular_componentGO:0045111 intermediate filament cytoskeleton IDA
 cellular_componentGO:0097418 neurofibrillary tangle IDA
 molecular_functionGO:0005198 structural molecule activity IEA
 molecular_functionGO:0005200 structural constituent of cytoskeleton TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008017 microtubule binding TAS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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