ENSG00000112343


Homo sapiens

Features
Gene ID: ENSG00000112343
  
Biological name :TRIM38
  
Synonyms : O00635 / TRIM38 / tripartite motif containing 38
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: p22.2
Gene start: 25962802
Gene end: 25991226
  
Corresponding Affymetrix probe sets: 203567_s_at (Human Genome U133 Plus 2.0 Array)   203568_s_at (Human Genome U133 Plus 2.0 Array)   203610_s_at (Human Genome U133 Plus 2.0 Array)   235084_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000349596
NCBI entrez gene - 10475     See in Manteia.
RefSeq - XM_017010175
RefSeq - NM_006355
RefSeq - XM_005248799
RefSeq - XM_005248800
RefSeq Peptide - NP_006346
swissprot - A0A024QZY4
swissprot - O00635
Ensembl - ENSG00000112343
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Trim38ENSMUSG00000064140Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P19474 / TRIM21 / tripartite motif containing 21ENSG0000013210942
Q9HCM9 / TRIM39 / tripartite motif containing 39ENSG0000020459940
Q8NG06 / TRIM58 / tripartite motif containing 58ENSG0000016272239
Q96F44 / TRIM11 / tripartite motif containing 11ENSG0000015437039
TRIM6 / Q9C030 / tripartite motif containing 6ENSG0000012123638
Q6AZZ1 / TRIM68 / tripartite motif containing 68ENSG0000016733335
TRIM6-TRIM34 / TRIM6-TRIM34 readthroughENSG0000025858835
TRIM4 / Q9C037 / tripartite motif containing 4ENSG0000014683334
Q8IYM9 / TRIM22 / tripartite motif containing 22ENSG0000013227433
TRIM5 / Q9C035 / tripartite motif containing 5ENSG0000013225633
Q9Y577 / TRIM17 / tripartite motif containing 17ENSG0000016293133
Q9BYJ4 / TRIM34 / tripartite motif containing 34ENSG0000025865932
TRIM39-RPP21 / TRIM39-RPP21 readthroughENSG0000024816732
Q495X7 / TRIM60 / tripartite motif containing 60ENSG0000017697931
A6NK02 / TRIM75P / tripartite motif containing 75, pseudogeneENSG0000025037430


Protein motifs (from Interpro)
Interpro ID Name
 IPR000315  B-box-type zinc finger
 IPR001841  Zinc finger, RING-type
 IPR001870  B30.2/SPRY domain
 IPR003877  SPRY domain
 IPR003879  Butyrophylin-like, SPRY domain
 IPR006574  SPRY-associated
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR017907  Zinc finger, RING-type, conserved site
 IPR035790  E3 ubiquitin-protein ligase TRIM38, PRY/SPRY domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0032648 regulation of interferon-beta production IEA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IDA
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0045070 positive regulation of viral genome replication IEA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0046598 positive regulation of viral entry into host cell IDA
 biological_processGO:0050687 negative regulation of defense response to virus IEA
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity IDA
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IDA
 biological_processGO:0060333 interferon-gamma-mediated signaling pathway TAS
 biological_processGO:0070936 protein K48-linked ubiquitination IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0004871 obsolete signal transducer activity HMP
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Interferon gamma signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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