ENSG00000134121


Homo sapiens

Features
Gene ID: ENSG00000134121
  
Biological name :CHL1
  
Synonyms : cell adhesion molecule L1 like / CHL1 / O00533
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: p26.3
Gene start: 196596
Gene end: 409417
  
Corresponding Affymetrix probe sets: 204591_at (Human Genome U133 Plus 2.0 Array)   234583_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000395239
Ensembl peptide - ENSP00000390440
Ensembl peptide - ENSP00000397445
Ensembl peptide - ENSP00000483512
Ensembl peptide - ENSP00000413628
Ensembl peptide - ENSP00000413109
Ensembl peptide - ENSP00000403311
Ensembl peptide - ENSP00000256509
Ensembl peptide - ENSP00000380628
NCBI entrez gene - 10752     See in Manteia.
OMIM - 607416
RefSeq - XM_017005573
RefSeq - XM_011533292
RefSeq - XM_011533294
RefSeq - XM_011533295
RefSeq - XM_011533296
RefSeq - XM_017005566
RefSeq - XM_017005567
RefSeq - XM_017005568
RefSeq - XM_017005569
RefSeq - XM_017005570
RefSeq - XM_017005571
RefSeq - XM_017005572
RefSeq - NM_001253387
RefSeq - NM_001253388
RefSeq - NM_006614
RefSeq - XM_006712938
RefSeq - XM_006712939
RefSeq - XM_006712940
RefSeq Peptide - NP_006605
RefSeq Peptide - NP_001240316
RefSeq Peptide - NP_001240317
swissprot - C9J905
swissprot - F8WEP4
swissprot - C9JW79
swissprot - O00533
swissprot - A0A087X0M8
swissprot - H7C0J0
swissprot - C9JH37
swissprot - C9JEY3
Ensembl - ENSG00000134121
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 chl1aENSDARG00000077881Danio rerio
 chl1bENSDARG00000103109Danio rerio
 CHL1ENSGALG00000037856Gallus gallus
 Chl1ENSMUSG00000030077Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NRCAM / Q92823 / neuronal cell adhesion moleculeENSG0000009112941
L1CAM / P32004 / L1 cell adhesion moleculeENSG0000019891038
NFASC / O94856 / neurofascinENSG0000016353136
CNTN2 / Q02246 / contactin 2ENSG0000018414423
CNTN4 / Q8IWV2 / contactin 4ENSG0000014461922
CNTN1 / Q12860 / contactin 1ENSG0000001823622
CNTN5 / O94779 / contactin 5ENSG0000014997222
CNTN3 / Q9P232 / contactin 3ENSG0000011380522
CNTN6 / Q9UQ52 / contactin 6ENSG0000013411521


Protein motifs (from Interpro)
Interpro ID Name
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR003961  Fibronectin type III
 IPR007110  Immunoglobulin-like domain
 IPR013098  Immunoglobulin I-set
 IPR013151  Immunoglobulin
 IPR013783  Immunoglobulin-like fold
 IPR026966  Neurofascin/L1/NrCAM, C-terminal domain
 IPR036116  Fibronectin type III superfamily
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001764 neuron migration IEA
 biological_processGO:0007155 cell adhesion TAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0007411 axon guidance IEA
 biological_processGO:0008344 adult locomotory behavior IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0031103 axon regeneration IEA
 biological_processGO:0031175 neuron projection development IEA
 biological_processGO:0035640 exploration behavior IEA
 biological_processGO:0043524 negative regulation of neuron apoptotic process IEA
 biological_processGO:0050890 cognition IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0045177 apical part of cell IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0002020 protease binding IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
CHL1 interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000109971 HSPA8 / P11142 / heat shock protein family A (Hsp70) member 8  / complex / reaction
 ENSG00000099250 NRP1 / O14786 / neuropilin 1  / reaction / complex
 ENSG00000029534 ANK1 / P16157 / ankyrin 1  / reaction / complex
 ENSG00000164171 ITGA2 / P17301 / integrin subunit alpha 2  / complex / reaction
 ENSG00000213949 ITGA1 / P56199 / integrin subunit alpha 1  / reaction / complex
 ENSG00000150093 ITGB1 / P05556 / integrin subunit beta 1  / complex / reaction
 ENSG00000134115 CNTN6 / Q9UQ52 / contactin 6  / complex / reaction
 ENSG00000143127 ITGA10 / O75578 / integrin subunit alpha 10  / reaction / complex






 

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