ENSG00000143127


Homo sapiens

Features
Gene ID: ENSG00000143127
  
Biological name :ITGA10
  
Synonyms : integrin subunit alpha 10 / ITGA10 / O75578
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q21.1
Gene start: 145891208
Gene end: 145910189
  
Corresponding Affymetrix probe sets: 206766_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000358310
Ensembl peptide - ENSP00000439894
NCBI entrez gene - 8515     See in Manteia.
OMIM - 604042
RefSeq - XM_017002628
RefSeq - NM_001303040
RefSeq - NM_001303041
RefSeq - NM_003637
RefSeq - XM_017002623
RefSeq - XM_017002624
RefSeq - XM_017002625
RefSeq - XM_017002626
RefSeq - XM_005277436
RefSeq - XM_011510083
RefSeq - XM_011510084
RefSeq - XM_017002622
RefSeq Peptide - NP_001289970
RefSeq Peptide - NP_003628
RefSeq Peptide - NP_001289969
swissprot - O75578
Ensembl - ENSG00000143127
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 itga10ENSDARG00000002507Danio rerio
 Itga10ENSMUSG00000090210Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ITGA11 / Q9UKX5 / integrin subunit alpha 11ENSG0000013780944
ITGA1 / P56199 / integrin subunit alpha 1ENSG0000021394936
ITGA2 / P17301 / integrin subunit alpha 2ENSG0000016417133
ITGAM / P11215 / integrin subunit alpha MENSG0000016989627
ITGAL / P20701 / integrin subunit alpha LENSG0000000584427
ITGAD / Q13349 / integrin subunit alpha DENSG0000015688627
ITGAX / P20702 / integrin subunit alpha XENSG0000014067826
ITGAE / P38570 / integrin subunit alpha EENSG0000008345726
ITGA7 / Q13683 / integrin subunit alpha 7ENSG0000013542421
ITGA6 / P23229 / integrin subunit alpha 6ENSG0000009140920
ITGA3 / P26006 / integrin subunit alpha 3ENSG0000000588420
ITGA8 / P53708 / integrin subunit alpha 8ENSG0000007794319
ITGA4 / P13612 / integrin subunit alpha 4ENSG0000011523219
ITGA9 / Q13797 / integrin subunit alpha 9ENSG0000014466819
ITGA5 / P08648 / integrin subunit alpha 5ENSG0000016163819
ITGAV / P06756 / integrin subunit alpha VENSG0000013844819
ITGA2B / P08514 / integrin subunit alpha 2bENSG0000000596118


Protein motifs (from Interpro)
Interpro ID Name
 IPR000413  Integrin alpha chain
 IPR002035  von Willebrand factor, type A
 IPR013517  FG-GAP repeat
 IPR013519  Integrin alpha beta-propellor
 IPR013649  Integrin alpha-2
 IPR032695  Integrin domain superfamily
 IPR036465  von Willebrand factor A-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007160 cell-matrix adhesion TAS
 biological_processGO:0007229 integrin-mediated signaling pathway IMP
 biological_processGO:0030198 extracellular matrix organization TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0008305 integrin complex TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0034680 integrin alpha10-beta1 complex IDA
 molecular_functionGO:0005518 collagen binding TAS
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0098639 collagen binding involved in cell-matrix adhesion IMP


Pathways (from Reactome)
Pathway description
Integrin cell surface interactions
CHL1 interactions
Platelet Adhesion to exposed collagen


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000150093 ITGB1 / P05556 / integrin subunit beta 1  / complex
 ENSG00000134121 CHL1 / O00533 / cell adhesion molecule L1 like  / reaction / complex






 

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