ENSG00000137809


Homo sapiens

Features
Gene ID: ENSG00000137809
  
Biological name :ITGA11
  
Synonyms : integrin subunit alpha 11 / ITGA11 / Q9UKX5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: -1
Band: q23
Gene start: 68296533
Gene end: 68432162
  
Corresponding Affymetrix probe sets: 1554819_a_at (Human Genome U133 Plus 2.0 Array)   222899_at (Human Genome U133 Plus 2.0 Array)   233335_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000327290
Ensembl peptide - ENSP00000403392
NCBI entrez gene - 22801     See in Manteia.
OMIM - 604789
RefSeq - XM_011521363
RefSeq - NM_001004439
RefSeq - XM_005254228
RefSeq Peptide - NP_001004439
swissprot - Q9UKX5
Ensembl - ENSG00000137809
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 itga11aENSDARG00000036086Danio rerio
 itga11bENSDARG00000007950Danio rerio
 ITGA11ENSGALG00000008007Gallus gallus
 Itga11ENSMUSG00000032243Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ITGA10 / O75578 / integrin subunit alpha 10ENSG0000014312743
ITGA1 / P56199 / integrin subunit alpha 1ENSG0000021394939
ITGA2 / P17301 / integrin subunit alpha 2ENSG0000016417134
ITGAM / P11215 / integrin subunit alpha MENSG0000016989627
ITGAD / Q13349 / integrin subunit alpha DENSG0000015688627
ITGAL / P20701 / integrin subunit alpha LENSG0000000584427
ITGAX / P20702 / integrin subunit alpha XENSG0000014067826
ITGAE / P38570 / integrin subunit alpha EENSG0000008345725
ITGA4 / P13612 / integrin subunit alpha 4ENSG0000011523220
ITGA9 / Q13797 / integrin subunit alpha 9ENSG0000014466820
ITGA5 / P08648 / integrin subunit alpha 5ENSG0000016163819
ITGA8 / P53708 / integrin subunit alpha 8ENSG0000007794319
ITGA7 / Q13683 / integrin subunit alpha 7ENSG0000013542419
ITGA3 / P26006 / integrin subunit alpha 3ENSG0000000588419
ITGA6 / P23229 / integrin subunit alpha 6ENSG0000009140919
ITGAV / P06756 / integrin subunit alpha VENSG0000013844818
ITGA2B / P08514 / integrin subunit alpha 2bENSG0000000596118


Protein motifs (from Interpro)
Interpro ID Name
 IPR000413  Integrin alpha chain
 IPR002035  von Willebrand factor, type A
 IPR013517  FG-GAP repeat
 IPR013519  Integrin alpha beta-propellor
 IPR013649  Integrin alpha-2
 IPR032695  Integrin domain superfamily
 IPR036465  von Willebrand factor A-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001649 osteoblast differentiation HDA
 biological_processGO:0006929 substrate-dependent cell migration IMP
 biological_processGO:0007155 cell adhesion TAS
 biological_processGO:0007160 cell-matrix adhesion TAS
 biological_processGO:0007229 integrin-mediated signaling pathway IMP
 biological_processGO:0007517 muscle organ development TAS
 biological_processGO:0030198 extracellular matrix organization TAS
 biological_processGO:0033627 cell adhesion mediated by integrin IMP
 biological_processGO:0038065 collagen-activated signaling pathway IMP
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005925 focal adhesion IDA
 cellular_componentGO:0008305 integrin complex TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0034681 integrin alpha11-beta1 complex IDA
 molecular_functionGO:0005518 collagen binding TAS
 molecular_functionGO:0038064 collagen receptor activity IMP
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0098639 collagen binding involved in cell-matrix adhesion IMP


Pathways (from Reactome)
Pathway description
Integrin cell surface interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000150093 ITGB1 / P05556 / integrin subunit beta 1  / complex






 

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