ENSG00000144668


Homo sapiens

Features
Gene ID: ENSG00000144668
  
Biological name :ITGA9
  
Synonyms : integrin subunit alpha 9 / ITGA9 / Q13797
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: p22.2
Gene start: 37452115
Gene end: 37823514
  
Corresponding Affymetrix probe sets: 1555335_at (Human Genome U133 Plus 2.0 Array)   1555336_a_at (Human Genome U133 Plus 2.0 Array)   206009_at (Human Genome U133 Plus 2.0 Array)   227297_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000264741
Ensembl peptide - ENSP00000406533
Ensembl peptide - ENSP00000397258
NCBI entrez gene - 3680     See in Manteia.
OMIM - 603963
RefSeq - NM_002207
RefSeq Peptide - NP_002198
swissprot - E9PDS3
swissprot - H7C2L1
swissprot - Q13797
Ensembl - ENSG00000144668
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 itga9ENSDARG00000032435Danio rerio
 ITGA9ENSGALG00000029378Gallus gallus
 Itga9ENSMUSG00000039115Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ITGA4 / P13612 / integrin subunit alpha 4ENSG0000011523242
ITGA5 / P08648 / integrin subunit alpha 5ENSG0000016163826
ITGA7 / Q13683 / integrin subunit alpha 7ENSG0000013542426
ITGAV / P06756 / integrin subunit alpha VENSG0000013844825
ITGA8 / P53708 / integrin subunit alpha 8ENSG0000007794325
ITGA6 / P23229 / integrin subunit alpha 6ENSG0000009140925
ITGA3 / P26006 / integrin subunit alpha 3ENSG0000000588423
ITGA11 / Q9UKX5 / integrin subunit alpha 11ENSG0000013780923
ITGA2B / P08514 / integrin subunit alpha 2bENSG0000000596123
ITGA1 / P56199 / integrin subunit alpha 1ENSG0000021394922
ITGA10 / O75578 / integrin subunit alpha 10ENSG0000014312722
ITGAD / Q13349 / integrin subunit alpha DENSG0000015688622
ITGAL / P20701 / integrin subunit alpha LENSG0000000584422
ITGAX / P20702 / integrin subunit alpha XENSG0000014067822
ITGAM / P11215 / integrin subunit alpha MENSG0000016989622
ITGAE / P38570 / integrin subunit alpha EENSG0000008345721
ITGA2 / P17301 / integrin subunit alpha 2ENSG0000016417121


Protein motifs (from Interpro)
Interpro ID Name
 IPR000413  Integrin alpha chain
 IPR013517  FG-GAP repeat
 IPR013519  Integrin alpha beta-propellor
 IPR013649  Integrin alpha-2
 IPR018184  Integrin alpha chain, C-terminal cytoplasmic region, conserved site
 IPR032695  Integrin domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IGI
 biological_processGO:0007229 integrin-mediated signaling pathway IEA
 biological_processGO:0030198 extracellular matrix organization TAS
 biological_processGO:0030593 neutrophil chemotaxis IEA
 biological_processGO:0042060 wound healing IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0008305 integrin complex TAS
 cellular_componentGO:0009925 basal plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0034679 integrin alpha9-beta1 complex IEA
 molecular_functionGO:0005518 collagen binding IEA
 molecular_functionGO:0043236 laminin binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Integrin cell surface interactions
ECM proteoglycans
Signal transduction by L1


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000118785 SPP1 / P10451 / secreted phosphoprotein 1  / complex / reaction
 ENSG00000041982 TNC / P24821 / tenascin C  / complex / reaction
 ENSG00000150093 ITGB1 / P05556 / integrin subunit beta 1  / complex
 ENSG00000162692 VCAM1 / P19320 / vascular cell adhesion molecule 1  / reaction / complex






 

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