ENSG00000083457


Homo sapiens

Features
Gene ID: ENSG00000083457
  
Biological name :ITGAE
  
Synonyms : integrin subunit alpha E / ITGAE / P38570
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: p13.2
Gene start: 3714628
Gene end: 3801243
  
Corresponding Affymetrix probe sets: 205055_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000263087
Ensembl peptide - ENSP00000467977
NCBI entrez gene - 3682     See in Manteia.
OMIM - 604682
RefSeq - XM_017024587
RefSeq - NM_002208
RefSeq - XM_011523827
RefSeq - XM_011523828
RefSeq - XM_017024586
RefSeq - XM_011523823
RefSeq - XM_011523825
RefSeq Peptide - NP_002199
swissprot - P38570
swissprot - K7EQU0
Ensembl - ENSG00000083457
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 itgae.1ENSDARG00000098012Danio rerio
 itgae.2ENSDARG00000057787Danio rerio
 ItgaeENSMUSG00000005947Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ITGAM / P11215 / integrin subunit alpha MENSG0000016989626
ITGAX / P20702 / integrin subunit alpha XENSG0000014067826
ITGAD / Q13349 / integrin subunit alpha DENSG0000015688626
ITGA10 / O75578 / integrin subunit alpha 10ENSG0000014312725
ITGA11 / Q9UKX5 / integrin subunit alpha 11ENSG0000013780925
ITGAL / P20701 / integrin subunit alpha LENSG0000000584425
ITGA2 / P17301 / integrin subunit alpha 2ENSG0000016417124
ITGA1 / P56199 / integrin subunit alpha 1ENSG0000021394924
ITGA9 / Q13797 / integrin subunit alpha 9ENSG0000014466818
ITGA3 / P26006 / integrin subunit alpha 3ENSG0000000588418
ITGA7 / Q13683 / integrin subunit alpha 7ENSG0000013542418
ITGAV / P06756 / integrin subunit alpha VENSG0000013844817
ITGA8 / P53708 / integrin subunit alpha 8ENSG0000007794317
ITGA6 / P23229 / integrin subunit alpha 6ENSG0000009140917
ITGA5 / P08648 / integrin subunit alpha 5ENSG0000016163817
ITGA4 / P13612 / integrin subunit alpha 4ENSG0000011523217
ITGA2B / P08514 / integrin subunit alpha 2bENSG0000000596116


Protein motifs (from Interpro)
Interpro ID Name
 IPR000413  Integrin alpha chain
 IPR002035  von Willebrand factor, type A
 IPR013517  FG-GAP repeat
 IPR013519  Integrin alpha beta-propellor
 IPR013649  Integrin alpha-2
 IPR018184  Integrin alpha chain, C-terminal cytoplasmic region, conserved site
 IPR032695  Integrin domain superfamily
 IPR036465  von Willebrand factor A-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007229 integrin-mediated signaling pathway IEA
 biological_processGO:0030198 extracellular matrix organization TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0008305 integrin complex TAS
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Integrin cell surface interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000039068 CDH1 / P12830 / cadherin 1  / reaction / complex
 ENSG00000139626 ITGB7 / P26010 / integrin subunit beta 7  / complex






 

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