ENSG00000156886


Homo sapiens

Features
Gene ID: ENSG00000156886
  
Biological name :ITGAD
  
Synonyms : integrin subunit alpha D / ITGAD / Q13349
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: p11.2
Gene start: 31393312
Gene end: 31426505
  
Corresponding Affymetrix probe sets: 1560686_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000373854
NCBI entrez gene - 3681     See in Manteia.
OMIM - 602453
RefSeq - XM_017023215
RefSeq - NM_001318185
RefSeq - NM_005353
RefSeq - XM_011545844
RefSeq - XM_011545845
RefSeq - XM_011545847
RefSeq - XM_011545835
RefSeq - XM_011545836
RefSeq - XM_011545837
RefSeq - XM_011545838
RefSeq - XM_011545839
RefSeq - XM_011545841
RefSeq - XM_011545842
RefSeq - XM_011545843
RefSeq Peptide - NP_005344
RefSeq Peptide - NP_001305114
swissprot - Q13349
Ensembl - ENSG00000156886
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 itgamENSDARG00000096587Danio rerio
 si:dkey-32n7.4ENSDARG00000002956Danio rerio
 ENSGALG00000041298Gallus gallus
 ItgadENSMUSG00000070369Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ITGAX / P20702 / integrin subunit alpha XENSG0000014067865
ITGAM / P11215 / integrin subunit alpha MENSG0000016989658
ITGAL / P20701 / integrin subunit alpha LENSG0000000584432
ITGA11 / Q9UKX5 / integrin subunit alpha 11ENSG0000013780927
ITGA10 / O75578 / integrin subunit alpha 10ENSG0000014312727
ITGAE / P38570 / integrin subunit alpha EENSG0000008345727
ITGA1 / P56199 / integrin subunit alpha 1ENSG0000021394926
ITGA2 / P17301 / integrin subunit alpha 2ENSG0000016417125
ITGA9 / Q13797 / integrin subunit alpha 9ENSG0000014466820
ITGA5 / P08648 / integrin subunit alpha 5ENSG0000016163820
ITGA7 / Q13683 / integrin subunit alpha 7ENSG0000013542419
ITGA4 / P13612 / integrin subunit alpha 4ENSG0000011523219
ITGAV / P06756 / integrin subunit alpha VENSG0000013844819
ITGA2B / P08514 / integrin subunit alpha 2bENSG0000000596119
ITGA3 / P26006 / integrin subunit alpha 3ENSG0000000588418
ITGA6 / P23229 / integrin subunit alpha 6ENSG0000009140918
ITGA8 / P53708 / integrin subunit alpha 8ENSG0000007794318


Protein motifs (from Interpro)
Interpro ID Name
 IPR000413  Integrin alpha chain
 IPR002035  von Willebrand factor, type A
 IPR013517  FG-GAP repeat
 IPR013519  Integrin alpha beta-propellor
 IPR013649  Integrin alpha-2
 IPR018184  Integrin alpha chain, C-terminal cytoplasmic region, conserved site
 IPR032695  Integrin domain superfamily
 IPR036465  von Willebrand factor A-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006955 immune response NAS
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007229 integrin-mediated signaling pathway IEA
 biological_processGO:0030198 extracellular matrix organization TAS
 biological_processGO:0034113 heterotypic cell-cell adhesion IMP
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0008305 integrin complex TAS
 cellular_componentGO:0009986 cell surface IC
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
Integrin cell surface interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000171557 FGG / P02679 / fibrinogen gamma chain  / reaction / complex
 ENSG00000160255 ITGB2 / P05107 / integrin subunit beta 2  / complex
 ENSG00000171560 FGA / P02671 / fibrinogen alpha chain  / complex / reaction
 ENSG00000171564 FGB / P02675 / fibrinogen beta chain  / complex / reaction






 

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