MP:0000060 | delayed bone ossification | "late onset of the formation of bone" [J:40203] |
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Allelic Composition: Juntm1Wag/Juntm1Wag,Tg(Junb)1598Angl/0 Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0000077 | abnormal interparietal bone morphology | "malformed bone of the cranium; lies above and anterior to the occipital bone " [J:61509] |
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Allelic Composition: Juntm1Wag/Juntm1Wag,Tg(Junb)1598Angl/0 Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0000078 | abnormal supraoccipital bone morphology | "malformed upper part of the occipital bone" [J:61509] |
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Allelic Composition: Juntm1Wag/Juntm1Wag,Tg(Junb)1598Angl/0 Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0000102 | abnormal nasal bone morphology | "malformed elongated rectangular bone that forms part of the nasal bridge" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:17489] |
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Allelic Composition: Juntm1Wag/Juntm1Wag,Tg(Junb)1598Angl/0 Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0000106 | abnormal basisphenoid bone morphology | "malformed base of the sphenoid bone" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55583] |
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Allelic Composition: Juntm1Wag/Juntm1Wag,Tg(Junb)1598Angl/0 Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0000107 | abnormal frontal bone morphology | "malformed bone forming the forehead and part of the eye orbit" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:17489] |
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Allelic Composition: Juntm1Wag/Juntm1Wag,Tg(Junb)1598Angl/0 Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0000109 | abnormal parietal bone morphology | "malformed curved bone forming part of the vault of the cranium" [J:17489] |
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Allelic Composition: Juntm1Wag/Juntm1Wag,Tg(Junb)1598Angl/0 Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0000116 | abnormal tooth development | "anomalous formation of the teeth" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Juntm1Wag/Juntm1Wag,Tg(Junb)1598Angl/0 Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0000141 | abnormal vertebral body morphology | "malformed main portion of the vertebra anterior to the vertebral canal" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55583] |
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Allelic Composition: Juntm1Wag/Juntm1Wag,Tg(Junb)1598Angl/0 Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0000159 | abnormal xiphoid process | "malformed posterior tip of the sternum" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:42932] |
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Allelic Composition: Juntm1Wag/Juntm1Wag,Tg(Junb)1598Angl/0 Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0000245 | abnormal erythropoiesis | "atypical process of red blood cell formation" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Juntm1Wag/Juntm1Wag,Tg(Junb)1598Angl/0 Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Sp1tm1Phi/Sp1+,Sp3tm1Sus/Sp3+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0000438 | abnormal skull morphology | "anomalous structure or development of the cranium" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Juntm1Wag/Juntm1Wag,Tg(Junb)1598Angl/0 Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Sp1tm1Phi/Sp1+,Sp3tm1Sus/Sp3+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0000600 | liver hypoplasia | "reduced size of liver due to decreased cell number " [J:57631] |
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Allelic Composition: Juntm1Wag/Juntm1Wag,Tg(Junb)1598Angl/0 Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0000601 | small liver | "reduced size of the liver" [J:23170] |
Show
Allelic Composition: Sp1tm1Phi/Sp1+,Sp3tm1Sus/Sp3+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0000706 | small thymus | "reduced size of the thymus" [J:36561, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:31167] |
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Allelic Composition: Juntm1Wag/Juntm1Wag,Tg(Junb)1598Angl/0 Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0001175 | abnormal lung morphology | "malformed organ of respiration" [J:35802] |
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Allelic Composition: Sp1tm1Phi/Sp1+,Sp3tm1Sus/Sp3+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0001265 | reduced body size | "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170] |
Show
Allelic Composition: Juntm1Wag/Juntm1Wag,Tg(Junb)1598Angl/0 Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Sp1tm1Phi/Sp1+,Sp3tm1Sus/Sp3+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0001293 | anophthalmia | "congenital absence of all tissues of the eyes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CML, J:71979] |
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Allelic Composition: Sp1tm1Phi/Sp1+,Sp3tm1Sus/Sp3+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0001577 | anemia | "less than normal levels of red blood cells, hemoglobin or volume of packed red blood cells " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370] |
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Allelic Composition: Sp1tm1Phi/Sp1+,Sp3tm1Sus/Sp3+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0001711 | abnormal placenta | |
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Allelic Composition: Sp1tm1Phi/Sp1+,Sp3tm1Sus/Sp3+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0001716 | abnormal placental labyrinth | "malformed structure where embryonic blood vessels are surrounded by trophoblast cells and maternal blood" [J:23171] |
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Allelic Composition: Juntm1Wag/Juntm1Wag,Tg(Junb)1598Angl/0 Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0001786 | skin edema | "accumulation of an excessive amount of fluid in the skin" [J:65039] |
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Allelic Composition: Sp1tm1Phi/Sp1+,Sp3tm1Sus/Sp3+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0001953 | respiratory failure | "cessation of or failure to commence breathing" [MGI:cls, J:60159] |
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Allelic Composition: Juntm1Wag/Juntm1Wag,Tg(Junb)1598Angl/0 Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0002144 | abnormal B lymphocyte development | "atypical production of or inability to produce mature B cells, and/or accumulation of B cell precursors" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Juntm1Wag/Juntm1Wag,Tg(Junb)1598Angl/0 Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0002270 | abnormal alveoli morphology | "any structural anomaly of the outpouching of the respiratory system where gas exchange occurs" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Juntm1Wag/Juntm1Wag,Tg(Junb)1598Angl/0 Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0002650 | abnormal ameloblast morphology | "malformation of the epithelial cells of the inner layer of the enamel organ of the developing tooth" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, il:Ira Lu , Mouse Genome Informatics Curator] |
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Allelic Composition: Juntm1Wag/Juntm1Wag,Tg(Junb)1598Angl/0 Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0002896 | abnormal bone mineralization | "defect in the process by which minerals are deposited into bone" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Juntm1Wag/Juntm1Wag,Tg(Junb)1598Angl/0 Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0003072 | abnormal metatarsal bone morphology | "anomaly in the five bones of the hindpaws that articulate proximally with the cuneiform and cuboid bones of the tarsus and distally with the phlanges" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, Anatomy of the Rat:Greene, EC, Hafner Publishing Co, 1935] |
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Allelic Composition: Juntm1Wag/Juntm1Wag,Tg(Junb)1598Angl/0 Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0003073 | abnormal metacarpal bone morphology | "anomaly in the five bones of the forepaws that articulate proximally with the carpal bones and distally with the phlanges" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, Anatomy of the Rat:Greene, EC, Hafner Publishing Co, 1935] |
Show
Allelic Composition: Juntm1Wag/Juntm1Wag,Tg(Junb)1598Angl/0 Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0003402 | decreased liver weight | "reduced average weight of the bile-secreting exocrine gland" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Sp1tm1Phi/Sp1+,Sp3tm1Sus/Sp3+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0003419 | delayed endochondral bone ossification | "late onset of bone formation in bones that form from cartilage" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:94631] |
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Allelic Composition: Juntm1Wag/Juntm1Wag,Tg(Junb)1598Angl/0 Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0003420 | delayed intramembranous bone ossification | "late onset of bone formation in bones that form without a cartilagenous intermediate including the cranium and clavicle" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:94631] |
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Allelic Composition: Juntm1Wag/Juntm1Wag,Tg(Junb)1598Angl/0 Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0003717 | pallor | "an unnatural paleness to the skin, generally attributable to anemia" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Sp1tm1Phi/Sp1+,Sp3tm1Sus/Sp3+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0003843 | abnormal sagittal suture morphology | "malformation of the articulation between the parietal bones" [smb:Susan M Bello, Mouse Genome Informatics Curator, Taber s Cyclopedic Medical Dictionary:19th edition: ISBN N 0-8036-0655-99] |
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Allelic Composition: Juntm1Wag/Juntm1Wag,Tg(Junb)1598Angl/0 Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0004448 | abnormal presphenoid bone morphology | "any structural anomaly of the anterior part of the body of the sphenoid bone in front of the basisphenoid; it is usually a separate bone in the young or fetus, but becomes a part of the sphenoid in the adult" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Juntm1Wag/Juntm1Wag,Tg(Junb)1598Angl/0 Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0004607 | abnormal cervical atlas morphology | "any structural anomaly of the first (topmost, C1) cervical vertebra which supports the globe of the head" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Juntm1Wag/Juntm1Wag,Tg(Junb)1598Angl/0 Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0004921 | decreased placenta weight | "reduction in the weight of the organ of metabolic interchange between fetus and mother" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Sp1tm1Phi/Sp1+,Sp3tm1Sus/Sp3+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0005306 | abnormal phalanx morphology | "aberrant structure of any of the long bones of the digits" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Juntm1Wag/Juntm1Wag,Tg(Junb)1598Angl/0 Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Sp1tm1Phi/Sp1+,Sp3tm1Sus/Sp3+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0008075 | decreased CD4-positive T cell number | "reduced number of the subset of T lymphocytes that carry the CD4 marker, recognize intravesicular peptides bound to MHC class-II molecules, and turn on antibody production" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Juntm1Wag/Juntm1Wag,Tg(Junb)1598Angl/0 Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0008271 | abnormal bone ossification | "any anomaly in the formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance" [GO:0001503] |
Show
Allelic Composition: Sp1tm1Phi/Sp1+,Sp3tm1Sus/Sp3+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0008277 | abnormal sternum ossification | "anomaly in the process of the formation of the sternum bone by the replacement of cartilage tissue with mineralized bone" [GO:0001958, MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"] |
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Allelic Composition: Juntm1Wag/Juntm1Wag,Tg(Junb)1598Angl/0 Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0008395 | abnormal osteoblast differentiation | "atypical production of or inability to produce bone-forming cells, which normally form an osseous matrix (osteoid) in which they become enclosed as an osteocytes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Juntm1Wag/Juntm1Wag,Tg(Junb)1598Angl/0 Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0008801 | abnormal erythroid progenitor cell morphology | "any structural anomaly of a progenitor cell committed to the erythroid lineage" [CL:0000038] |
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Allelic Composition: Juntm1Wag/Juntm1Wag,Tg(Junb)1598Angl/0 Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0008877 | abnormal DNA methylation | "any anomaly in the covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine of DNA" [GO:0006306] |
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Allelic Composition: Nr3c1tm1Gsc/Nr3c1tm1Gsc Genetic Background: involves: 129P2/OlaHsd * 129/Sv
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MP:0008958 | abnormal glycogen cell morphology | "any structural anomaly of a glycogen-accumulating trophoblast cell that arises in the junctional zone of the placenta" [PMID:17039549] |
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Allelic Composition: Juntm1Wag/Juntm1Wag,Tg(Junb)1598Angl/0 Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0008959 | abnormal spongiotrophoblast cell morphology | "any structural anomaly of a trophoblast cell that arises in the junctional zone of the placenta" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Juntm1Wag/Juntm1Wag,Tg(Junb)1598Angl/0 Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Sp1tm1Phi/Sp1+,Sp3tm1Sus/Sp3+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0008973 | decreased erythroid progenitor cell number | "reduced numbers of progenitors of the erythrocyte lineage" [CL:0000038, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Sp1tm1Phi/Sp1+,Sp3tm1Sus/Sp3+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0008989 | abnormal liver sinusoid morphology | "any structural anomaly of the hepatic distensible vascular blood channels lined with highly fenestrated endothelial cells that function to exchange fluids, nutrients, proteins and wastes" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
Show
Allelic Composition: Sp1tm1Phi/Sp1+,Sp3tm1Sus/Sp3+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0009431 | decreased fetal weight | "reduced weight of a fetus compared to controls (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Sp1tm1Phi/Sp1+,Sp3tm1Sus/Sp3+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0009703 | decreased birth body size | "reduction in average body size at birth compared to controls" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Juntm1Wag/Juntm1Wag,Tg(Junb)1598Angl/0 Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0010029 | abnormal basicranium morphology | "any structural anomaly of the sloping floor of the cranial cavity that is comprised of parts of the ethmoidal, occipital and sphenoid bones" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
Show
Allelic Composition: Juntm1Wag/Juntm1Wag,Tg(Junb)1598Angl/0 Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0010128 | hypovolemia | "an abnormally decreased amount of space occupied by blood in the vessels" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Sp1tm1Phi/Sp1+,Sp3tm1Sus/Sp3+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0011083 | complete lethality at weaning | "premature death at weaning age of all organisms of a given genotype in a population, often due to the inability to make the transition to solid food" [MGI:csmith] |
Show
Allelic Composition: Sp1tm1Phi/Sp1+,Sp3tm1Sus/Sp3+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0011087 | complete neonatal lethality | "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith] |
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Allelic Composition: Juntm1Wag/Juntm1Wag,Tg(Junb)1598Angl/0 Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0011109 | partial lethality throughout fetal growth and development | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith] |
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Allelic Composition: Sp1tm1Phi/Sp1+,Sp3tm1Sus/Sp3+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0011525 | abnormal placenta intervillous maternal lacunae morphology | "any structural anomaly of the spaces of the placenta occupied by maternal blood, into which the fetal labyrinth villi project" [MGI:csmith] |
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Allelic Composition: Sp1tm1Phi/Sp1+,Sp3tm1Sus/Sp3+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0011527 | disorganized placental labyrinth | "derangement of the placental layers where embryonic blood vessels are surrounded by trophoblast cells and maternal blood" [MGI:csmith] |
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Allelic Composition: Sp1tm1Phi/Sp1+,Sp3tm1Sus/Sp3+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0012099 | decreased spongiotrophoblast size | "reduction of the size of the middle layer of the placenta between the outermost giant cells and the innermost labyrinth layer; it has a structural role and also produces several layer-specific secreted factors" [MGI:csmith] |
Show
Allelic Composition: Juntm1Wag/Juntm1Wag,Tg(Junb)1598Angl/0 Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Sp1tm1Phi/Sp1+,Sp3tm1Sus/Sp3+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0012109 | decreased trophoblast glycogen cell number | "reduced number of the glycogen-accumulating trophoblast cells that arise in the junctional zone of the placenta" [MGI:csmith] |
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Allelic Composition: Sp1tm1Phi/Sp1+,Sp3tm1Sus/Sp3+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0030542 | abnormal dentin development | "any anomaly in the process whose specific outcome is the formation of dentin, the hard portion of the tooth surrounding the pulp, covered by enamel on the crown and cementum on the root; dentinogenesis begins prior to enamel formation and is initiated by the odontoblasts of the dental pulp; dentin is derived from the dental papilla of the tooth germ; after apposition of predentin and maturation into dentin, the cell bodies of the odontoblasts remain in the pulp inside the tooth, along its outer wall; unlike enamel, dentin continues to form throughout life and can be initiated in response to stimuli, such as tooth decay or attrition" [GO:0097187, https://en.wikipedia.org/wiki/Dentin] |
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Allelic Composition: Juntm1Wag/Juntm1Wag,Tg(Junb)1598Angl/0 Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0030544 | abnormal enamel development | "any anomaly in the process whose specific outcome is the formation of dental enamel, the hard outer coating of the exposed portion of the tooth; amelogenesis occurs after the first establishment of dentin, via cells known as ameloblasts, and can generally be divided into two broad stages: (i) a secretory stage that involves proteins and an organic matrix forming a partially mineralized enamel and (ii) a maturation stage which completes enamel mineralization" [GO:0097186, https://en.wikipedia.org/wiki/Tooth_enamel] |
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Allelic Composition: Juntm1Wag/Juntm1Wag,Tg(Junb)1598Angl/0 Genetic Background: involves: 129S2/SvPas * C57BL/6
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