ENSMUSG00000030165


Mus musculus

Features
Gene ID: ENSMUSG00000030165
  
Biological name :Klrd1
  
Synonyms : Klrd1 / Natural killer cells antigen CD94 / O54707
  
Possible biological names infered from orthology : killer cell lectin like receptor D1 / Q13241
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: F3
Gene start: 129591782
Gene end: 129598775
  
Corresponding Affymetrix probe sets: 10542214 (MoGene1.0st)   1460245_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000032268
Ensembl peptide - ENSMUSP00000144712
Ensembl peptide - ENSMUSP00000123703
Ensembl peptide - ENSMUSP00000113399
Ensembl peptide - ENSMUSP00000107694
NCBI entrez gene - 16643     See in Manteia.
MGI - MGI:1196275
RefSeq - XM_006505656
RefSeq - NM_010654
RefSeq - XM_006505655
RefSeq Peptide - NP_034784
swissprot - E0CZ14
swissprot - E9Q3T9
swissprot - O54707
swissprot - D3Z626
swissprot - A0A0N4SUJ9
Ensembl - ENSMUSG00000030165
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KLRD1ENSG00000134539Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Klre1 / Q8CJC7 / Killer cell lectin-like receptor subfamily E member 1 ENSMUSG0000005024134
Klrk1 / O54709 / NKG2-D type II integral membrane protein / P26718* / killer cell lectin like receptor K1*ENSMUSG0000003014928
Klri1 / B2KG20 / Killer cell lectin-like receptor subfamily I member 1 ENSMUSG0000006761025
Klrc2 / KLRC1* / KLRC4* / KLRC3* / Q07444* / O43908* / P26715* / P26717* / AC068775.1* / KLRC4-KLRK1* / KLRC4-KLRK1 readthrough* / killer cell lectin like receptor C1* / killer cell lectin ...ENSMUSG0000005273624
Klrc1 / KLRC4* / KLRC3* / KLRC2* / Q07444* / O43908* / P26715* / P26717* / AC068775.1* / KLRC4-KLRK1* / KLRC4-KLRK1 readthrough* / killer cell lectin like receptor C1* / killer cell lectin ...ENSMUSG0000003016723
Klri2 / Q5DT36 / Killer cell lectin-like receptor subfamily I member 2 ENSMUSG0000004393222
Klrc3 / KLRC1* / KLRC4* / KLRC2* / Q07444* / O43908* / P26715* / P26717* / AC068775.1* / KLRC4-KLRK1* / KLRC4-KLRK1 readthrough* / killer cell lectin like receptor C1* / killer cell lectin ...ENSMUSG0000003302721


Protein motifs (from Interpro)
Interpro ID Name
 IPR001304  C-type lectin-like
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR033992  Natural killer cell receptor-like, C-type lectin-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002228 natural killer cell mediated immunity IEA
 cellular_componentGO:0009897 external side of plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043235 receptor complex IEA
 molecular_functionGO:0023024 MHC class I protein complex binding IEA
 molecular_functionGO:0023030 MHC class Ib protein binding, via antigen binding groove IEA
 molecular_functionGO:0030246 carbohydrate binding IEA
 molecular_functionGO:1990405 protein antigen binding IEA


Pathways (from Reactome)
Pathway description
DAP12 interactions
DAP12 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000031834 O08908 / Pik3r2 / Phosphatidylinositol 3-kinase regulatory subunit beta / O00459* / AC007192.1* / phosphoinositide-3-kinase regulatory subunit 2*  / complex / reaction
 ENSMUSG00000041417 P26450 / Pik3r1 / phosphoinositide-3-kinase regulatory subunit 1 / P27986*  / reaction / complex
 ENSMUSG00000027665 P42337 / Pik3ca / Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform / P42336* / phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha*  / reaction / complex
 ENSMUSG00000021457 Syk / P48025 / spleen tyrosine kinase / P43405* / spleen associated tyrosine kinase*  / complex / reaction
 ENSMUSG00000019843 Fyn / P39688 / Tyrosine-protein kinase Fyn / P06241* / FYN proto-oncogene, Src family tyrosine kinase*  / complex
 ENSMUSG00000000409 Lck / P06240 / Proto-onco tyrosine-protein kinase LCK / P06239* / LCK proto-oncogene, Src family tyrosine kinase*  / complex
 ENSMUSG00000032462 Pik3cb / Q8BTI9 / Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform / P42338* / phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta*  / reaction / complex
 ENSMUSG00000060802 B2m / P01887 / Beta-2-microglobulin / P61769*  / complex
 ENSMUSG00000030579 O54885 / Tyrobp / TYRO protein tyrosine kinase binding protein / O43914*  / reaction / complex






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr