ENSMUSG00000031394


Mus musculus

Features
Gene ID: ENSMUSG00000031394
  
Biological name :Opn1mw
  
Synonyms : Medium-wave-sensitive opsin 1 / O35599 / Opn1mw
  
Possible biological names infered from orthology : OPN1LW / OPN1MW2 / OPN1MW3 / opsin 1, long wave sensitive / opsin 1, medium wave sensitive / opsin 1, medium wave sensitive 2 / opsin 1, medium wave sensitive 3 / P04000 / P04001 / P0DN77 / P0DN78
  
Species: Mus musculus
  
Chr. number: X
Strand: 1
Band: A7.3
Gene start: 74127464
Gene end: 74150760
  
Corresponding Affymetrix probe sets: 10600317 (MoGene1.0st)   1419723_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000033771
Ensembl peptide - ENSMUSP00000118631
Ensembl peptide - ENSMUSP00000099000
NCBI entrez gene - 14539     See in Manteia.
MGI - MGI:1097692
RefSeq - NM_008106
RefSeq Peptide - NP_032132
swissprot - B1AYN8
swissprot - B1AYN7
swissprot - O35599
Ensembl - ENSMUSG00000031394
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q8AYN0ENSDARG00000044861Danio rerio
 Q9W6A7ENSDARG00000044862Danio rerio
 OPNPENSGALG00000004924Gallus gallus
 OPN1LWENSG00000102076Homo sapiens
 OPN1MWENSG00000268221Homo sapiens
 P0DN77ENSG00000166160Homo sapiens
 P0DN78ENSG00000269433Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Opn1sw / P51491 / Short-wave-sensitive opsin 1 / P03999* / opsin 1, short wave sensitive*ENSMUSG0000005883139
Rho / P15409 / Rhodopsin / P08100*ENSMUSG0000003032439
Opn3 / Q9WUK7 / Opsin-3 / Q9H1Y3*ENSMUSG0000002652526
Opn4 / Q9QXZ9 / Melanopsin / Q9UHM6* / opsin 4*ENSMUSG0000002179926
Rrh / O35214 / retinal pigment epithelium derived rhodopsin homolog / O14718*ENSMUSG0000002801222
Opn5 / Q6VZZ7 / Opsin-5 / Q6U736*ENSMUSG0000004397220


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000378  Opsin red/green sensitive
 IPR001760  Opsin
 IPR017452  GPCR, rhodopsin-like, 7TM
 IPR027430  Visual pigments (opsins) retinal binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007601 visual perception IEA
 biological_processGO:0007602 phototransduction IEA
 biological_processGO:0009584 detection of visible light IEA
 biological_processGO:0018298 protein-chromophore linkage IEA
 biological_processGO:0032467 positive regulation of cytokinesis ISO
 biological_processGO:0050896 response to stimulus IEA
 cellular_componentGO:0001750 photoreceptor outer segment IEA
 cellular_componentGO:0005886 plasma membrane ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008020 G-protein coupled photoreceptor activity IBA
 molecular_functionGO:0009881 photoreceptor activity IEA
 molecular_functionGO:0042802 identical protein binding ISS


Pathways (from Reactome)
Pathway description
The retinoid cycle in cones (daylight vision)
G alpha (i) signalling events
Opsins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002090 abnormal vision "inability or decreased ability to see " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gli2tm1Alj/Gli2tm1Alj,Gli3Xt-J/Gli3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H * CD-1

Allelic Composition: Opn1mwtm1(OPN1LW)Nat/Opn1mwtm1(OPN1LW)Nat
Genetic Background: involves: 129

Allelic Composition: Opn1mwtm1(OPN1LW)Nat/Y
Genetic Background: involves: 129

 MP:0011831 abnormal visual contrast sensitivity "any abnormality in the ability to distinguish between increments of light versus dark" [MGI:smb]
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Allelic Composition: LexmRetro/Lexm+
Genetic Background: involves: C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000009108 Gnat2 / P50149 / guanine nucleotide binding protein, alpha transducing 2 / P19087* / G protein subunit alpha transducin 2*  / complex / reaction
 ENSMUSG00000058831 Opn1sw / P51491 / Short-wave-sensitive opsin 1 / P03999* / opsin 1, short wave sensitive*  / reaction
 ENSMUSG00000043004 Gng2 / P63213 / guanine nucleotide binding protein (G protein), gamma 2 / P59768* / G protein subunit gamma 2*  / reaction / complex
 ENSMUSG00000029064 Gnb1 / P62874 / guanine nucleotide binding protein (G protein), beta 1 / P62873* / G protein subunit beta 1*  / complex / reaction
 ENSMUSG00000031394 Opn1mw / O35599 / Medium-wave-sensitive opsin 1 / P0DN78* / OPN1LW* / P04000* / P04001* / P0DN77* / OPN1MW2* / OPN1MW3* / opsin 1, long wave sensitive* / opsin 1, medium wave sensitive* / ...  / reaction
 ENSMUSG00000034837 Gnat1 / P20612 / guanine nucleotide binding protein, alpha transducing 1 / P11488* / G protein subunit alpha transducin 1*  / reaction / complex
 ENSMUSG00000030324 Rho / P15409 / Rhodopsin / P08100*  / reaction






 

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