ENSMUSG00000058831


Mus musculus

Features
Gene ID: ENSMUSG00000058831
  
Biological name :Opn1sw
  
Synonyms : Opn1sw / P51491 / Short-wave-sensitive opsin 1
  
Possible biological names infered from orthology : opsin 1, short wave sensitive / P03999
  
Species: Mus musculus
  
Chr. number: 6
Strand: -1
Band: A3.3
Gene start: 29376671
Gene end: 29388468
  
Corresponding Affymetrix probe sets: 10543591 (MoGene1.0st)   1418552_at (Mouse Genome 430 2.0 Array)   1449132_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000133745
Ensembl peptide - ENSMUSP00000079289
Ensembl peptide - ENSMUSP00000133534
NCBI entrez gene - 12057     See in Manteia.
MGI - MGI:99438
RefSeq - NM_007538
RefSeq Peptide - NP_031564
swissprot - P51491
swissprot - G3UX34
swissprot - G3UXM0
Ensembl - ENSMUSG00000058831
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 opn1sw1ENSDARG00000045677Danio rerio
 OPN1SWENSG00000128617Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rho / P15409 / Rhodopsin / P08100*ENSMUSG0000003032444
Opn1mw / O35599 / Medium-wave-sensitive opsin 1 / P0DN78* / OPN1LW* / P04000* / P04001* / P0DN77* / OPN1MW2* / OPN1MW3* / opsin 1, long wave sensitive* / opsin 1, medium wave sensitive* / ...ENSMUSG0000003139440
Opn4 / Q9QXZ9 / Melanopsin / Q9UHM6* / opsin 4*ENSMUSG0000002179928
Opn3 / Q9WUK7 / Opsin-3 / Q9H1Y3*ENSMUSG0000002652527
Rrh / O35214 / retinal pigment epithelium derived rhodopsin homolog / O14718*ENSMUSG0000002801222
Opn5 / Q6VZZ7 / Opsin-5 / Q6U736*ENSMUSG0000004397218


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR001521  Opsin, blue sensitive
 IPR001760  Opsin
 IPR017452  GPCR, rhodopsin-like, 7TM
 IPR027430  Visual pigments (opsins) retinal binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007601 visual perception IEA
 biological_processGO:0007602 phototransduction IEA
 biological_processGO:0009584 detection of visible light IEA
 biological_processGO:0018298 protein-chromophore linkage IEA
 biological_processGO:0050896 response to stimulus IEA
 cellular_componentGO:0001750 photoreceptor outer segment IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0008020 G-protein coupled photoreceptor activity IBA
 molecular_functionGO:0009881 photoreceptor activity IEA


Pathways (from Reactome)
Pathway description
The retinoid cycle in cones (daylight vision)
G alpha (i) signalling events
Opsins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0004022 abnormal cone electrophysiology "anomaly in the function of light adapted vision mediated by the cones" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Rock2Gt(OST440776)Lex/Rock2Gt(OST440776)Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J

 MP:0008586 disorganized photoreceptor outer segment "derangement of the pattern of the photoreceptor region that is rich in the visual pigment rhodopsin" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Rrm2bGt(OST85254)Lex/Rrm2bGt(OST85254)Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000031394 Opn1mw / O35599 / Medium-wave-sensitive opsin 1 / P0DN78* / OPN1LW* / P04000* / P04001* / P0DN77* / OPN1MW2* / OPN1MW3* / opsin 1, long wave sensitive* / opsin 1, medium wave sensitive* / ...  / reaction
 ENSMUSG00000030324 Rho / P15409 / Rhodopsin / P08100*  / reaction
 ENSMUSG00000058831 Opn1sw / P51491 / Short-wave-sensitive opsin 1 / P03999* / opsin 1, short wave sensitive*  / reaction
 ENSMUSG00000043004 Gng2 / P63213 / guanine nucleotide binding protein (G protein), gamma 2 / P59768* / G protein subunit gamma 2*  / complex / reaction
 ENSMUSG00000029064 Gnb1 / P62874 / guanine nucleotide binding protein (G protein), beta 1 / P62873* / G protein subunit beta 1*  / reaction / complex
 ENSMUSG00000034837 Gnat1 / P20612 / guanine nucleotide binding protein, alpha transducing 1 / P11488* / G protein subunit alpha transducin 1*  / complex / reaction
 ENSMUSG00000009108 Gnat2 / P50149 / guanine nucleotide binding protein, alpha transducing 2 / P19087* / G protein subunit alpha transducin 2*  / complex / reaction






 

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