ENSMUSG00000033595


Mus musculus

Features
Gene ID: ENSMUSG00000033595
  
Biological name :Lgi3
  
Synonyms : Leucine-rich repeat LGI family member 3 / Lgi3 / Q8K406
  
Possible biological names infered from orthology : Q8N145
  
Species: Mus musculus
  
Chr. number: 14
Strand: 1
Band: D2
Gene start: 70530685
Gene end: 70538324
  
Corresponding Affymetrix probe sets: 10416279 (MoGene1.0st)   1433667_at (Mouse Genome 430 2.0 Array)   1436238_at (Mouse Genome 430 2.0 Array)   1460546_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000046705
Ensembl peptide - ENSMUSP00000153920
NCBI entrez gene - 213469     See in Manteia.
MGI - MGI:2182619
RefSeq - NM_145219
RefSeq Peptide - NP_660254
swissprot - Q8K406
Ensembl - ENSMUSG00000033595
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lgi3ENSDARG00000041358Danio rerio
 LGI3ENSG00000168481Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Lgi1 / Q9JIA1 / Leucine-rich glioma-inactivated protein 1 / O95970* / leucine rich glioma inactivated 1*ENSMUSG0000006724252
Lgi2 / Q8K4Z0 / Leucine-rich repeat LGI family member 2 / Q8N0V4*ENSMUSG0000003925247
Lgi4 / Q8K1S1 / Leucine-rich repeat LGI family member 4 / Q8N135*ENSMUSG0000003656041
Lrig2 / Q52KR2 / leucine-rich repeats and immunoglobulin-like domains 2 / O94898*ENSMUSG0000003291323
Lrig3 / Q6P1C6 / Leucine-rich repeats and immunoglobulin-like domains protein 3 / Q6UXM1* / leucine rich repeats and immunoglobulin like domains 3*ENSMUSG0000002010522
Lrig1 / P70193 / Leucine-rich repeats and immunoglobulin-like domains protein 1 / Q96JA1* / leucine rich repeats and immunoglobulin like domains 1*ENSMUSG0000003002921
Adgra2 / Q91ZV8 / Adhesion G protein-coupled receptor A2 / Q96PE1*ENSMUSG0000003148618
Adgra3 / Q7TT36 / Adhesion G protein-coupled receptor A3 / Q8IWK6*ENSMUSG0000002909016
Vasn / Q9CZT5 / vasorin / Q6EMK4*ENSMUSG0000003964614
Adgra1 / Q8C4G9 / Adhesion G protein-coupled receptor A1 / Q86SQ6*ENSMUSG000000254758


Protein motifs (from Interpro)
Interpro ID Name
 IPR000483  Cysteine-rich flanking region, C-terminal
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR005492  Leucine-rich glioma-inactivated , EPTP repeat
 IPR009039  EAR
 IPR011041  Soluble quinoprotein glucose/sorbosone dehydrogenase
 IPR011042  Six-bladed beta-propeller, TolB-like
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006887 exocytosis IEA
 biological_processGO:0017157 regulation of exocytosis IDA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0008021 synaptic vesicle IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0045202 synapse IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
LGI-ADAM interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000030806 Stx1b / P61264 / Syntaxin-1B / P61266*  / complex / reaction
 ENSMUSG00000040537 Adam22 / Q9R1V6 / Disintegrin and metalloproteinase domain-containing protein 22 / Q9P0K1* / ADAM metallopeptidase domain 22*  / reaction / complex
 ENSMUSG00000025964 Adam23 / Q9R1V7 / Disintegrin and metalloproteinase domain-containing protein 23 / O75077* / ADAM metallopeptidase domain 23*  / complex / reaction
 ENSMUSG00000007207 Stx1a / O35526 / syntaxin 1A (brain) / Q16623* / syntaxin 1A*  / complex / reaction






 

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