ENSMUSG00000036111


Mus musculus

Features
Gene ID: ENSMUSG00000036111
  
Biological name :Lmo1
  
Synonyms : Lmo1 / Q924W9 / Rhombotin-1
  
Possible biological names infered from orthology : LIM domain only 1 / P25800
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: E3
Gene start: 109138572
Gene end: 109175207
  
Corresponding Affymetrix probe sets: 10566723 (MoGene1.0st)   1418478_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000146752
Ensembl peptide - ENSMUSP00000037079
Ensembl peptide - ENSMUSP00000146588
NCBI entrez gene - 109594     See in Manteia.
MGI - MGI:102812
RefSeq - XM_006507195
RefSeq - NM_001302205
RefSeq - NM_001302206
RefSeq - NM_057173
RefSeq Peptide - NP_476514
RefSeq Peptide - NP_001289134
RefSeq Peptide - NP_001289135
swissprot - A0A140LHX4
swissprot - A0A140LIB4
swissprot - Q3UZX1
swissprot - Q924W9
Ensembl - ENSMUSG00000036111
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LMO1ENSG00000166407Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Lmo3 / Q8BZL8 / Mus musculus LIM domain only 3 (Lmo3), transcript variant 2, mRNA. / Q8TAP4* / LIM domain only 3*ENSMUSG0000003022683
Lmo2 / P25801 / Rhombotin-2 / P25791* / LIM domain only 2*ENSMUSG0000003269850
Lmo4 / P61969 / LIM domain transcription factor LMO4 / P61968* / LIM domain only 4*ENSMUSG0000002826645
Lhx9 / Q9WUH2 / LIM/homeobox protein Lhx9 / Q9NQ69* / LIM homeobox 9*ENSMUSG0000001923038
Lhx2 / Q9Z0S2 / LIM/homeobox protein Lhx2 / P50458* / LIM homeobox 2*ENSMUSG0000000024738
Lhx4 / P53776 / LIM/homeobox protein Lhx4 / Q969G2* / LIM homeobox 4*ENSMUSG0000002646837
Isl2 / Q9CXV0 / Insulin enhancer protein ISL-2 / Q96A47* / ISL LIM homeobox 2*ENSMUSG0000003231836
Lmx1a / Q9JKU8 / LIM homeobox transcription factor 1-alpha / Q8TE12*ENSMUSG0000002668636
Lhx3 / P50481 / LIM homeobox protein 3 / Q9UBR4* / LIM homeobox 3*ENSMUSG0000002693436
Lhx6 / Q9R1R0 / Mus musculus LIM homeobox protein 6 (Lhx6), transcript variant 5, mRNA. / Q9UPM6* / LIM homeobox 6*ENSMUSG0000002689035
Lmx1b / LIM homeobox transcription factor 1 beta / O60663*ENSMUSG0000003876535
Isl1 / P61372 / Insulin enhancer protein ISL-1 / P61371* / ISL LIM homeobox 1*ENSMUSG0000004225834
Lhx8 / O35652 / LIM/homeobox protein Lhx8 / Q68G74* / LIM homeobox 8*ENSMUSG0000009622533
Lhx1 / P63006 / LIM/homeobox protein Lhx1 / P48742* / LIM homeobox 1*ENSMUSG0000001869831
Lhx5 / P61375 / LIM homeobox protein 5 / Q9H2C1* / LIM homeobox 5*ENSMUSG0000002959529


Protein motifs (from Interpro)
Interpro ID Name
 IPR001781  Zinc finger, LIM-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IGI
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0046013 regulation of T cell homeostatic proliferation IDA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
RUNX1 regulates transcription of genes involved in differentiation of HSCs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002082 postnatal lethality "premature death anytime after postnatal day 1 to weaning age (3 weeks)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Krastm4Tyj/Kras+,Tg(Mx1-cre)1Cgn/0
Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * CBA

Allelic Composition: Lmo1tm1Thr/Lmo1tm1Thr,Lmo3tm2Thr/Lmo3tm2Thr
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Lmo1tm2Thr/Lmo1tm2Thr,Lmo3tm1Thr/Lmo3tm1Thr
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Lmo1tm2Thr/Lmo1tm2Thr,Lmo3tm2Thr/Lmo3tm2Thr
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Lmo1tm2Thr/Lmo1tm2Thr,Lmo3tm2Thr/Lmo3tm2Thr
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Lmo1tm2Thr/Lmo1tm2Thr
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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