ENSMUSG00000038236


Mus musculus

Features
Gene ID: ENSMUSG00000038236
  
Biological name :Hoxa7
  
Synonyms : homeobox A7 / Hoxa7 / P02830
  
Possible biological names infered from orthology : P31268
  
Species: Mus musculus
  
Chr. number: 6
Strand: -1
Band: B3
Gene start: 52214491
Gene end: 52221854
  
Corresponding Affymetrix probe sets: 10544779 (MoGene1.0st)   1449499_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000138790
Ensembl peptide - ENSMUSP00000134610
Ensembl peptide - ENSMUSP00000048648
Ensembl peptide - ENSMUSP00000134641
Ensembl peptide - ENSMUSP00000140519
NCBI entrez gene - 15404     See in Manteia.
MGI - MGI:96179
RefSeq - NM_010455
RefSeq Peptide - NP_034585
swissprot - S4R2U5
swissprot - A0A087WR88
swissprot - G3UZS1
swissprot - G3UZU9
swissprot - P02830
Ensembl - ENSMUSG00000038236
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HOXA7ENSGALG00000026989Gallus gallus
 HOXA7ENSG00000122592Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Hoxb7 / P09024 / Homeobox protein Hox-B7 / P09629* / homeobox B7*ENSMUSG0000003872156
Hoxb6 / P09023 / Homeobox protein Hox-B6 / P17509* / homeobox B6*ENSMUSG0000000069044
Hoxb5 / P09079 / Homeobox protein Hox-B5 / P09067* / homeobox B5*ENSMUSG0000003870041
Hoxb8 / P09632 / Homeobox protein Hox-B8 / P17481* / homeobox B8*ENSMUSG0000005664839
Hoxa6 / P09092 / Homeobox protein Hox-A6 / P31267* / homeobox A6*ENSMUSG0000004321938
Hoxa5 / P09021 / Homeobox protein Hox-A5 / P20719* / homeobox A5*ENSMUSG0000003825338
Hoxd8 / P23463 / Homeobox protein Hox-D8 / P13378* / homeobox D8*ENSMUSG0000002710238
Hoxc8 / P09025 / Homeobox protein Hox-C8 / P31273* / homeobox C8*ENSMUSG0000000165738
Hoxc4 / Q08624 / homeobox C4 / P09017*ENSMUSG0000007539437
Hoxc6 / P10629 / Homeobox protein Hox-C6 / P09630* / homeobox C6*ENSMUSG0000000166136
Hoxc5 / P32043 / Homeobox protein Hox-C5 / Q00444* / homeobox C5*ENSMUSG0000002248534
Hoxa4 / homeobox A4 / Q00056*ENSMUSG0000000094234
Hoxd4 / P10628 / homeobox D4 / P09016*ENSMUSG0000010117434
Hoxd4 / P10628 / Homeobox protein Hox-D4 / P09016* / homeobox D4*ENSMUSG0000011595634
Hoxb4 / P10284 / Homeobox protein Hox-B4 / P17483* / homeobox B4*ENSMUSG0000003869232
Cdx1 / P18111 / Homeobox protein CDX-1 / P47902* / caudal type homeobox 1*ENSMUSG0000002461926
Cdx2 / P43241 / Homeobox protein CDX-2 / Q99626* / caudal type homeobox 2*ENSMUSG0000002964626
Cdx4 / Q07424 / Homeobox protein CDX-4 / O14627* / caudal type homeobox 4*ENSMUSG0000003132624


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR001827  Homeobox protein, antennapedia type, conserved site
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR017995  Homeobox protein, antennapedia type
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0001953 negative regulation of cell-matrix adhesion IEA
 biological_processGO:0002686 negative regulation of leukocyte migration IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0009952 anterior/posterior pattern specification IGI
 biological_processGO:0045617 negative regulation of keratinocyte differentiation IEA
 biological_processGO:0045656 negative regulation of monocyte differentiation IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048704 embryonic skeletal system morphogenesis IGI
 biological_processGO:0048863 stem cell differentiation IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0031965 nuclear membrane IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000154 rib fusion "appearance of one or more ribs as a single structure" [J:62022, J:62023]
Show

Allelic Composition: Sept6tm1Nosa/Sept6tm1Nosa
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Hoxa7tm1Mrc/Hoxa7+,Hoxb7tm1Mrc/Hoxb7tm1Mrc
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ

Allelic Composition: Hoxa7tm1Mrc/Hoxa7tm1Mrc,Hoxb7tm1Mrc/Hoxb7tm1Mrc
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ

 MP:0000706 small thymus "reduced size of the thymus" [J:36561, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:31167]
Show

Allelic Composition: Hoxa7tm1Mrc/Hoxa7tm1Mrc,Hoxb7tm1Mrc/Hoxb7tm1Mrc
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Sept6tm1Nosa/Sept6tm1Nosa
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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