ENSG00000122592


Homo sapiens

Features
Gene ID: ENSG00000122592
  
Biological name :HOXA7
  
Synonyms : homeobox A7 / HOXA7 / P31268
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: p15.2
Gene start: 27153716
Gene end: 27157936
  
Corresponding Affymetrix probe sets: 206847_s_at (Human Genome U133 Plus 2.0 Array)   235753_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000242159
Ensembl peptide - ENSP00000428563
NCBI entrez gene - 3204     See in Manteia.
OMIM - 142950
RefSeq - NM_006896
RefSeq Peptide - NP_008827
swissprot - E5RHM9
swissprot - P31268
Ensembl - ENSG00000122592
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HOXA7ENSGALG00000026989Gallus gallus
 Hoxa7ENSMUSG00000038236Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HOXB7 / P09629 / homeobox B7ENSG0000026002755
HOXB6 / P17509 / homeobox B6ENSG0000010851141
HOXB5 / P09067 / homeobox B5ENSG0000012007540
HOXA6 / P31267 / homeobox A6ENSG0000010600639
HOXD8 / P13378 / homeobox D8ENSG0000017587939
HOXA5 / P20719 / homeobox A5ENSG0000010600438
HOXC8 / P31273 / homeobox C8ENSG0000003796537
HOXC4 / P09017 / homeobox C4ENSG0000019835337
HOXB8 / P17481 / homeobox B8ENSG0000012006837
HOXC6 / P09630 / homeobox C6ENSG0000019775736
HOXA4 / Q00056 / homeobox A4ENSG0000019757635
HOXD4 / P09016 / homeobox D4ENSG0000017016635
HOXC5 / Q00444 / homeobox C5ENSG0000017278933
HOXB4 / P17483 / homeobox B4ENSG0000018274232
CDX2 / Q99626 / caudal type homeobox 2ENSG0000016555625
CDX1 / P47902 / caudal type homeobox 1ENSG0000011372225
AC012531.3ENSG0000027304923
CDX4 / O14627 / caudal type homeobox 4ENSG0000013126423


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR001827  Homeobox protein, antennapedia type, conserved site
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR017995  Homeobox protein, antennapedia type
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001525 angiogenesis IEP
 biological_processGO:0001953 negative regulation of cell-matrix adhesion IDA
 biological_processGO:0002686 negative regulation of leukocyte migration IDA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0009952 anterior/posterior pattern specification IEA
 biological_processGO:0045617 negative regulation of keratinocyte differentiation IDA
 biological_processGO:0045656 negative regulation of monocyte differentiation IDA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048704 embryonic skeletal system morphogenesis IEA
 biological_processGO:0048863 stem cell differentiation IEA
 cellular_componentGO:0005634 nucleus IC
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0031965 nuclear membrane IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0008134 transcription factor binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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