ENSG00000120075


Homo sapiens

Features
Gene ID: ENSG00000120075
  
Biological name :HOXB5
  
Synonyms : homeobox B5 / HOXB5 / P09067
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q21.32
Gene start: 48591257
Gene end: 48593961
  
Corresponding Affymetrix probe sets: 205600_x_at (Human Genome U133 Plus 2.0 Array)   205601_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000239151
NCBI entrez gene - 3215     See in Manteia.
OMIM - 142960
RefSeq - NM_002147
RefSeq Peptide - NP_002138
swissprot - P09067
Ensembl - ENSG00000120075
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Hoxb5ENSMUSG00000038700Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HOXA5 / P20719 / homeobox A5ENSG0000010600455
HOXC5 / Q00444 / homeobox C5ENSG0000017278936
HOXA7 / P31268 / homeobox A7ENSG0000012259235
HOXC4 / P09017 / homeobox C4ENSG0000019835333
HOXB7 / P09629 / homeobox B7ENSG0000026002733
HOXB6 / P17509 / homeobox B6ENSG0000010851133
HOXA6 / P31267 / homeobox A6ENSG0000010600632
HOXA4 / Q00056 / homeobox A4ENSG0000019757631
HOXD4 / P09016 / homeobox D4ENSG0000017016631
HOXB4 / P17483 / homeobox B4ENSG0000018274230
HOXC6 / P09630 / homeobox C6ENSG0000019775728
HOXB8 / P17481 / homeobox B8ENSG0000012006828
HOXD8 / P13378 / homeobox D8ENSG0000017587928
HOXC8 / P31273 / homeobox C8ENSG0000003796528
CDX1 / P47902 / caudal type homeobox 1ENSG0000011372225
AC012531.3ENSG0000027304924
CDX4 / O14627 / caudal type homeobox 4ENSG0000013126424
CDX2 / Q99626 / caudal type homeobox 2ENSG0000016555622


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR001827  Homeobox protein, antennapedia type, conserved site
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR017995  Homeobox protein, antennapedia type
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0009653 anatomical structure morphogenesis TAS
 biological_processGO:0009952 anterior/posterior pattern specification IEA
 biological_processGO:0045446 endothelial cell differentiation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048704 embryonic skeletal system morphogenesis IEA
 biological_processGO:0048706 embryonic skeletal system development IEA
 cellular_componentGO:0001650 fibrillar center IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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