ENSG00000197576


Homo sapiens

Features
Gene ID: ENSG00000197576
  
Biological name :HOXA4
  
Synonyms : homeobox A4 / HOXA4 / Q00056
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: p15.2
Gene start: 27128507
Gene end: 27130799
  
Corresponding Affymetrix probe sets: 206289_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000479166
Ensembl peptide - ENSP00000353151
Ensembl peptide - ENSP00000408845
Ensembl peptide - ENSP00000448015
NCBI entrez gene - 3201     See in Manteia.
OMIM - 142953
RefSeq - NM_002141
RefSeq Peptide - NP_002132
swissprot - H0YHX3
swissprot - Q00056
Ensembl - ENSG00000197576
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HOXA4ENSGALG00000022622Gallus gallus
 Hoxa4ENSMUSG00000000942Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HOXB4 / P17483 / homeobox B4ENSG0000018274247
HOXC4 / P09017 / homeobox C4ENSG0000019835343
HOXD4 / P09016 / homeobox D4ENSG0000017016642
HOXA5 / P20719 / homeobox A5ENSG0000010600427
HOXB5 / P09067 / homeobox B5ENSG0000012007526
HOXA7 / P31268 / homeobox A7ENSG0000012259225
HOXB7 / P09629 / homeobox B7ENSG0000026002724
HOXC5 / Q00444 / homeobox C5ENSG0000017278924
HOXB6 / P17509 / homeobox B6ENSG0000010851124
HOXC6 / P09630 / homeobox C6ENSG0000019775723
HOXD8 / P13378 / homeobox D8ENSG0000017587923
HOXB8 / P17481 / homeobox B8ENSG0000012006822
HOXA6 / P31267 / homeobox A6ENSG0000010600622
CDX2 / Q99626 / caudal type homeobox 2ENSG0000016555621
HOXC8 / P31273 / homeobox C8ENSG0000003796520
CDX1 / P47902 / caudal type homeobox 1ENSG0000011372220
CDX4 / O14627 / caudal type homeobox 4ENSG0000013126419
AC012531.3ENSG0000027304917


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR001827  Homeobox protein, antennapedia type, conserved site
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR017995  Homeobox protein, antennapedia type
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0009653 anatomical structure morphogenesis TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0016604 nuclear body IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
Activation of anterior HOX genes in hindbrain development during early embryogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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