ENSG00000108511


Homo sapiens

Features
Gene ID: ENSG00000108511
  
Biological name :HOXB6
  
Synonyms : homeobox B6 / HOXB6 / P17509
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q21.32
Gene start: 48595751
Gene end: 48604992
  
Corresponding Affymetrix probe sets: 205365_at (Human Genome U133 Plus 2.0 Array)   205366_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000225648
Ensembl peptide - ENSP00000420009
NCBI entrez gene - 3216     See in Manteia.
OMIM - 142961
RefSeq - XM_011524727
RefSeq - NM_018952
RefSeq - XM_005257283
RefSeq - XM_005257284
RefSeq Peptide - NP_061825
swissprot - P17509
Ensembl - ENSG00000108511
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000037619Gallus gallus
 Hoxb6ENSMUSG00000000690Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HOXA6 / P31267 / homeobox A6ENSG0000010600654
HOXB7 / P09629 / homeobox B7ENSG0000026002745
HOXA7 / P31268 / homeobox A7ENSG0000012259242
HOXB5 / P09067 / homeobox B5ENSG0000012007539
HOXC6 / P09630 / homeobox C6ENSG0000019775738
HOXA5 / P20719 / homeobox A5ENSG0000010600438
HOXB8 / P17481 / homeobox B8ENSG0000012006838
HOXD8 / P13378 / homeobox D8ENSG0000017587937
HOXD4 / P09016 / homeobox D4ENSG0000017016636
HOXB4 / P17483 / homeobox B4ENSG0000018274236
HOXC8 / P31273 / homeobox C8ENSG0000003796535
HOXC4 / P09017 / homeobox C4ENSG0000019835334
HOXA4 / Q00056 / homeobox A4ENSG0000019757634
HOXC5 / Q00444 / homeobox C5ENSG0000017278933
CDX1 / P47902 / caudal type homeobox 1ENSG0000011372227
CDX4 / O14627 / caudal type homeobox 4ENSG0000013126425
AC012531.3ENSG0000027304925
CDX2 / Q99626 / caudal type homeobox 2ENSG0000016555622


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR001827  Homeobox protein, antennapedia type, conserved site
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR017995  Homeobox protein, antennapedia type
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0009952 anterior/posterior pattern specification IEA
 biological_processGO:0034101 erythrocyte homeostasis IEA
 biological_processGO:0048704 embryonic skeletal system morphogenesis IEA
 biological_processGO:0048706 embryonic skeletal system development IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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