ENSG00000113722


Homo sapiens

Features
Gene ID: ENSG00000113722
  
Biological name :CDX1
  
Synonyms : caudal type homeobox 1 / CDX1 / P47902
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: q32
Gene start: 150166795
Gene end: 150184558
  
Corresponding Affymetrix probe sets: 206430_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000231656
Ensembl peptide - ENSP00000477928
NCBI entrez gene - 1044     See in Manteia.
OMIM - 600746
RefSeq - NM_001804
RefSeq Peptide - NP_001795
swissprot - A0A087WTJ6
swissprot - P47902
Ensembl - ENSG00000113722
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cdx1aENSDARG00000114554Danio rerio
 CDX1ENSGALG00000005679Gallus gallus
 Cdx1ENSMUSG00000024619Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CDX2 / Q99626 / caudal type homeobox 2ENSG0000016555650
CDX4 / O14627 / caudal type homeobox 4ENSG0000013126440
HOXB5 / P09067 / homeobox B5ENSG0000012007525
HOXB7 / P09629 / homeobox B7ENSG0000026002724
HOXA4 / Q00056 / homeobox A4ENSG0000019757624
HOXB4 / P17483 / homeobox B4ENSG0000018274224
HOXD4 / P09016 / homeobox D4ENSG0000017016623
HOXB6 / P17509 / homeobox B6ENSG0000010851123
HOXC5 / Q00444 / homeobox C5ENSG0000017278923
HOXA6 / P31267 / homeobox A6ENSG0000010600623
HOXC4 / P09017 / homeobox C4ENSG0000019835323
HOXA5 / P20719 / homeobox A5ENSG0000010600422
HOXA7 / P31268 / homeobox A7ENSG0000012259222
HOXD8 / P13378 / homeobox D8ENSG0000017587921
HOXC8 / P31273 / homeobox C8ENSG0000003796520
HOXB8 / P17481 / homeobox B8ENSG0000012006820
HOXC6 / P09630 / homeobox C6ENSG0000019775720
AC012531.3ENSG0000027304916


Protein motifs (from Interpro)
Interpro ID Name
 IPR000047  Helix-turn-helix motif
 IPR001356  Homeobox domain
 IPR006820  Caudal-like activation domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007389 pattern specification process IEA
 biological_processGO:0009887 animal organ morphogenesis TAS
 biological_processGO:0009948 anterior/posterior axis specification IBA
 biological_processGO:0009952 anterior/posterior pattern specification IEA
 biological_processGO:0014807 regulation of somitogenesis IEA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0060349 bone morphogenesis IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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