ENSG00000131264


Homo sapiens

Features
Gene ID: ENSG00000131264
  
Biological name :CDX4
  
Synonyms : caudal type homeobox 4 / CDX4 / O14627
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: 1
Band: q13.2
Gene start: 73447254
Gene end: 73455245
  
Corresponding Affymetrix probe sets: 221340_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000362613
NCBI entrez gene - 1046     See in Manteia.
OMIM - 300025
RefSeq - NM_005193
RefSeq Peptide - NP_005184
swissprot - O14627
Ensembl - ENSG00000131264
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cdx4ENSDARG00000036292Danio rerio
 ENSGALG00000007656Gallus gallus
 CDX4ENSGALG00000007657Gallus gallus
 Cdx4ENSMUSG00000031326Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CDX2 / Q99626 / caudal type homeobox 2ENSG0000016555640
CDX1 / P47902 / caudal type homeobox 1ENSG0000011372237
HOXB5 / P09067 / homeobox B5ENSG0000012007523
HOXA4 / Q00056 / homeobox A4ENSG0000019757621
HOXA5 / P20719 / homeobox A5ENSG0000010600421
HOXD4 / P09016 / homeobox D4ENSG0000017016620
HOXB6 / P17509 / homeobox B6ENSG0000010851120
HOXA6 / P31267 / homeobox A6ENSG0000010600620
HOXD8 / P13378 / homeobox D8ENSG0000017587920
HOXC4 / P09017 / homeobox C4ENSG0000019835320
HOXC5 / Q00444 / homeobox C5ENSG0000017278919
HOXB7 / P09629 / homeobox B7ENSG0000026002719
HOXA7 / P31268 / homeobox A7ENSG0000012259219
HOXB8 / P17481 / homeobox B8ENSG0000012006819
HOXB4 / P17483 / homeobox B4ENSG0000018274219
HOXC8 / P31273 / homeobox C8ENSG0000003796518
HOXC6 / P09630 / homeobox C6ENSG0000019775717
AC012531.3ENSG0000027304914


Protein motifs (from Interpro)
Interpro ID Name
 IPR000047  Helix-turn-helix motif
 IPR001356  Homeobox domain
 IPR006820  Caudal-like activation domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001568 blood vessel development IEA
 biological_processGO:0001890 placenta development IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0009887 animal organ morphogenesis IBA
 biological_processGO:0009948 anterior/posterior axis specification IBA
 biological_processGO:0009952 anterior/posterior pattern specification IEA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IMP
 biological_processGO:0060711 labyrinthine layer development IEA
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IMP
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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