ENSG00000106004


Homo sapiens

Features
Gene ID: ENSG00000106004
  
Biological name :HOXA5
  
Synonyms : homeobox A5 / HOXA5 / P20719
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: p15.2
Gene start: 27141052
Gene end: 27143668
  
Corresponding Affymetrix probe sets: 213844_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000222726
NCBI entrez gene - 3202     See in Manteia.
OMIM - 142952
RefSeq - NM_019102
RefSeq Peptide - NP_061975
swissprot - P20719
Ensembl - ENSG00000106004
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hoxa5aENSDARG00000102501Danio rerio
 HOXA5ENSGALG00000025929Gallus gallus
 Hoxa5ENSMUSG00000038253Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HOXB5 / P09067 / homeobox B5ENSG0000012007555
HOXC5 / Q00444 / homeobox C5ENSG0000017278936
HOXD4 / P09016 / homeobox D4ENSG0000017016634
HOXA7 / P31268 / homeobox A7ENSG0000012259233
HOXC4 / P09017 / homeobox C4ENSG0000019835333
HOXB4 / P17483 / homeobox B4ENSG0000018274232
HOXA4 / Q00056 / homeobox A4ENSG0000019757632
HOXB7 / P09629 / homeobox B7ENSG0000026002731
HOXB6 / P17509 / homeobox B6ENSG0000010851131
HOXA6 / P31267 / homeobox A6ENSG0000010600630
HOXD8 / P13378 / homeobox D8ENSG0000017587930
HOXB8 / P17481 / homeobox B8ENSG0000012006829
HOXC6 / P09630 / homeobox C6ENSG0000019775729
HOXC8 / P31273 / homeobox C8ENSG0000003796527
CDX2 / Q99626 / caudal type homeobox 2ENSG0000016555623
AC012531.3ENSG0000027304923
CDX4 / O14627 / caudal type homeobox 4ENSG0000013126422
CDX1 / P47902 / caudal type homeobox 1ENSG0000011372221


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR001827  Homeobox protein, antennapedia type, conserved site
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR017995  Homeobox protein, antennapedia type
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001501 skeletal system development IEA
 biological_processGO:0002009 morphogenesis of an epithelium IEA
 biological_processGO:0003016 respiratory system process IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007389 pattern specification process IEA
 biological_processGO:0007585 respiratory gaseous exchange IEA
 biological_processGO:0009952 anterior/posterior pattern specification IEA
 biological_processGO:0010870 positive regulation of receptor biosynthetic process IDA
 biological_processGO:0016477 cell migration IEA
 biological_processGO:0016525 negative regulation of angiogenesis IMP
 biological_processGO:0030324 lung development IEA
 biological_processGO:0030878 thyroid gland development IEA
 biological_processGO:0033599 regulation of mammary gland epithelial cell proliferation IEA
 biological_processGO:0035264 multicellular organism growth IEA
 biological_processGO:0043065 positive regulation of apoptotic process IDA
 biological_processGO:0045639 positive regulation of myeloid cell differentiation IDA
 biological_processGO:0045647 negative regulation of erythrocyte differentiation IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048286 lung alveolus development IEA
 biological_processGO:0048704 embryonic skeletal system morphogenesis IEA
 biological_processGO:0048706 embryonic skeletal system development IEA
 biological_processGO:0060435 bronchiole development IEA
 biological_processGO:0060439 trachea morphogenesis IEA
 biological_processGO:0060441 epithelial tube branching involved in lung morphogenesis IEA
 biological_processGO:0060480 lung goblet cell differentiation IEA
 biological_processGO:0060481 lobar bronchus epithelium development IEA
 biological_processGO:0060484 lung-associated mesenchyme development IEA
 biological_processGO:0060535 trachea cartilage morphogenesis IEA
 biological_processGO:0060536 cartilage morphogenesis IEA
 biological_processGO:0060574 intestinal epithelial cell maturation IEA
 biological_processGO:0060638 mesenchymal-epithelial cell signaling IEA
 biological_processGO:0060644 mammary gland epithelial cell differentiation IEA
 biological_processGO:0060749 mammary gland alveolus development IEA
 biological_processGO:0060764 cell-cell signaling involved in mammary gland development IEA
 cellular_componentGO:0005634 nucleus IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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