ENSMUSG00000041308


Mus musculus

Features
Gene ID: ENSMUSG00000041308
  
Biological name :Sntb2
  
Synonyms : Q61235 / Sntb2 / syntrophin, basic 2
  
Possible biological names infered from orthology : Q13425 / syntrophin beta 2
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: D3
Gene start: 106935750
Gene end: 107019714
  
Corresponding Affymetrix probe sets: 10575120 (MoGene1.0st)   1420371_at (Mouse Genome 430 2.0 Array)   1420372_at (Mouse Genome 430 2.0 Array)   1436986_at (Mouse Genome 430 2.0 Array)   1437003_at (Mouse Genome 430 2.0 Array)   1449840_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000148684
Ensembl peptide - ENSMUSP00000037324
NCBI entrez gene - 20650     See in Manteia.
MGI - MGI:101771
RefSeq - NM_009229
RefSeq Peptide - NP_033255
swissprot - B7ZNU9
swissprot - Q542S9
swissprot - Q61235
Ensembl - ENSMUSG00000041308
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sntb2ENSDARG00000051763Danio rerio
 SNTB2ENSGALG00000027482Gallus gallus
 SNTB2ENSG00000168807Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Sntb1 / Q99L88 / Beta-1-syntrophin / Q13884* / syntrophin beta 1*ENSMUSG0000006042956
Snta1 / Q61234 / Alpha-1-syntrophin / Q13424* / syntrophin alpha 1*ENSMUSG0000002748846
Sntg2 / Q925E0 / Gamma-2-syntrophin / Q9NY99* / syntrophin gamma 2*ENSMUSG0000002067224
Sntg1 / gamma-1-syntrophin isoform 3 / Q9NSN8* / syntrophin gamma 1*ENSMUSG0000002590923
Gopc / Q8BH60 / golgi associated PDZ and coiled-coil motif containing / AL132671.2*ENSMUSG0000001986115
B / Lin7b / O88951 / Q9HAP6* / lin-7 homolog B, crumbs cell polarity complex component*ENSMUSG0000000387210
C / Lin7c / O88952 / Q9NUP9* / lin-7 homolog C, crumbs cell polarity complex component*ENSMUSG0000002716210
Lin7a / Q8JZS0 / lin-7 homolog A (C. elegans) / O14910* / lin-7 homolog A, crumbs cell polarity complex component*ENSMUSG0000001990610


Protein motifs (from Interpro)
Interpro ID Name
 IPR001478  PDZ domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR015482  Syntrophin
 IPR028550  Beta-2-syntrophin
 IPR036034  PDZ superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030658 transport vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0045202 synapse IDA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005198 structural molecule activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005516 calmodulin binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001053 abnormal neuromuscular synapse "malformed or absent membrane to membrane contact of a motor axon and a muscle myofiber resulting in aberrant transmission of nerve impulses" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159, J:47439]
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Allelic Composition: Snta1tm1Scf/Snta1tm1Scf,Sntb2tm1Maad/Sntb2tm1Maad
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001402 hypoactivity "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]
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Allelic Composition: Efnb2tm5.1Kln/Efnb2tm5.1Kln,Flt4tm1Ali/Flt4+
Genetic Background: involves: C57BL/6

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Efnb2tm5.1Kln/Efnb2tm5.1Kln,Flt4tm1Ali/Flt4+
Genetic Background: involves: C57BL/6

 MP:0004835 abnormal miniature endplate potential "defect in the size or duration of spontaneous currents detected in PNS postsynaptic cells that occur in the absence of an excitatory impulse" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Snta1tm1Scf/Snta1tm1Scf,Sntb2tm1Maad/Sntb2tm1Maad
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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