ENSMUSG00000048015


Mus musculus

Features
Gene ID: ENSMUSG00000048015
  
Biological name :Neurod4
  
Synonyms : Neurod4 / neurogenic differentiation 4 / O09105
  
Possible biological names infered from orthology : neuronal differentiation 4 / Q9HD90
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: D3
Gene start: 130268152
Gene end: 130280240
  
Corresponding Affymetrix probe sets: 10373680 (MoGene1.0st)   1418054_at (Mouse Genome 430 2.0 Array)   1418055_at (Mouse Genome 430 2.0 Array)   1436694_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000051379
NCBI entrez gene - 11923     See in Manteia.
MGI - MGI:108055
RefSeq - NM_007501
RefSeq - XM_006513142
RefSeq - NM_001329489
RefSeq - NM_001329490
RefSeq Peptide - NP_001316419
RefSeq Peptide - NP_031527
RefSeq Peptide - NP_001316418
swissprot - O09105
swissprot - Q545C0
Ensembl - ENSMUSG00000048015
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 neurod4ENSDARG00000003469Danio rerio
 NEUROD4ENSGALG00000034306Gallus gallus
 Q9HD90ENSG00000123307Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q60867 / Neurod1 / Neurogenic differentiation factor 1 / Q13562* / neuronal differentiation 1*ENSMUSG0000003470154
Q62414 / Neurod2 / neurogenic differentiation 2 / Q15784* / neuronal differentiation 2*ENSMUSG0000003825543
P48986 / Neurod6 / neurogenic differentiation 6 / Q96NK8* / neuronal differentiation 6*ENSMUSG0000003798441
P70660 / Neurog1 / Neurogenin-1 / Q92886*ENSMUSG0000004890421
Neurog2 / neurogenin 2 / Q9H2A3*ENSMUSG0000002796719
P70661 / Neurog3 / Neurogenin-3 / Q9Y4Z2*ENSMUSG0000004431218
1 / Atoh1 / P48985 / Q92858* / atonal bHLH transcription factor 1*ENSMUSG0000007304316
Q9QYC3 / Bhlha15 / Class A basic helix-loop-helix protein 15 / Q7RTS1* / basic helix-loop-helix family member a15*ENSMUSG0000005227114
8 / Atoh8 / Q99NA2 / Q96SQ7* / atonal bHLH transcription factor 8*ENSMUSG0000003762113
7 / Atoh7 / Q9Z2E5 / Q8N100* / atonal bHLH transcription factor 7*ENSMUSG0000003681613


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR016637  Neurogenic differentiation factor NeuroD
 IPR022575  Neurogenic differentiation factor, domain of unknown function
 IPR032651  Neurogenic differentiation factor 4
 IPR036638  Helix-loop-helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001764 neuron migration IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007219 Notch signaling pathway IGI
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0007405 neuroblast proliferation IGI
 biological_processGO:0010001 glial cell differentiation IGI
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0035881 amacrine cell differentiation IDA
 biological_processGO:0043010 camera-type eye development IGI
 biological_processGO:0045165 cell fate commitment IGI
 biological_processGO:0045597 positive regulation of cell differentiation IDA
 biological_processGO:0048666 neuron development IMP
 biological_processGO:0060041 retina development in camera-type eye IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000852 small cerebellum "reduced size of cerebellum" [MGI:CLS, J:17203, J:67524]
Show

Allelic Composition: Wnt9bclf1/Wnt9bclf1,clf2/clf2+
Genetic Background: AEJ.A/Jur

 MP:0000872 abnormal external granule cell layer "malformation of the transient layer of the cerebellar cortex which is composed of the dividing and migrating granule cells" [tc:Teresa Chu , Mouse Genome Informatics Curator]
Show

Allelic Composition: Wnt9bclf1/Wnt9bclf1,clf2/clf2+
Genetic Background: AEJ.A/Jur

 MP:0000890 thin cerebellar molecular layer "reduced width of the outer of the three cortical layers of the cerebellum" [J:46854]
Show

Allelic Composition: Wnt9bclf1/Wnt9bclf1,clf2/clf2+
Genetic Background: AEJ.A/Jur

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Wnt9bclf1/Wnt9bclf1,clf2/clf2+
Genetic Background: AEJ.A/Jur

 MP:0001327 reduced retinal photoreceptor cell number "fewer than the expected number of rods and/or cones" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Wnt9bclf1/Wnt9bclf1,clf2/clf2+
Genetic Background: AEJ.A/Jur

Allelic Composition: Neurod1tm1Jle/Neurod1tm1Jle,Neurod4tm1Kag/Neurod4tm1Kag,Neurog2tm1Fgu/Neurog2tm1Fgu
Genetic Background: involves: 129/Sv * C57BL/6 * CBA * ICR

Allelic Composition: Ascl1tm1And/Ascl1tm1And,Neurod1tm1Jle/Neurod1tm1Jle,Neurod4tm1Kag/Neurod4tm1Kag
Genetic Background: involves: 129/Sv * C57BL/6 * CBA * ICR

Allelic Composition: Neurod4tm1Kag/Neurod4tm1Kag,Neurog2tm1Fgu/Neurog2tm1Fgu
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * ICR

 MP:0001330 abnormal optic nerve morphology "malformation, misprojection or atrophy in the second cranial nerve which is responsible for conveying visual information from the retina to the brain" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Wnt9bclf1/Wnt9bclf1,clf2/clf2+
Genetic Background: AEJ.A/Jur

 MP:0001393 ataxia "inability to coordinate voluntary muscular movements" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:67231]
Show

Allelic Composition: Wnt9bclf1/Wnt9bclf1,clf2/clf2+
Genetic Background: AEJ.A/Jur

 MP:0001422 abnormal drinking behavior "an altered pattern of fluid consumption or altered preference for particular fluids" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Wnt9bclf1/Wnt9bclf1,clf2/clf2+
Genetic Background: AEJ.A/Jur

 MP:0001525 impaired balance "reduced ability of an animal to maintain equilibrium" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:64962, J:17123]
Show

Allelic Composition: Wnt9bclf1/Wnt9bclf1,clf2/clf2+
Genetic Background: AEJ.A/Jur

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Wnt9bclf1/Wnt9bclf1,clf2/clf2+
Genetic Background: AEJ.A/Jur

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Wnt9bclf1/Wnt9bclf1,clf2/clf2+
Genetic Background: AEJ.A/Jur

 MP:0002983 increased retinal ganglion cell number "greater number of cells in the innermost nuclear layer of the retina, which projects axons through the optic nerve to the brain " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, il:Ira Lu , Mouse Genome Informatics Curator]
Show

Allelic Composition: Neurod1tm1Jle/Neurod1tm1Jle,Neurod4tm1Kag/Neurod4tm1Kag
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6 * CBA * ICR

Allelic Composition: Ascl1tm1And/Ascl1tm1And,Neurod4tm1Kag/Neurod4tm1Kag,Neurog2tm1Fgu/Neurog2tm1Fgu
Genetic Background: involves: 129/Sv * C57BL/6 * CBA * ICR

Allelic Composition: Ascl1tm1And/Ascl1tm1And,Neurod1tm1Jle/Neurod1tm1Jle,Neurod4tm1Kag/Neurod4tm1Kag
Genetic Background: involves: 129/Sv * C57BL/6 * CBA * ICR

 MP:0003727 abnormal retinal layer morphology "malformation in any of the layers that make up the retina" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Neurod1tm1Jle/Neurod1tm1Jle,Neurod4tm1Kag/Neurod4tm1Kag,Neurog2tm1Fgu/Neurog2tm1Fgu
Genetic Background: involves: 129/Sv * C57BL/6 * CBA * ICR

Allelic Composition: Ascl1tm1And/Ascl1tm1And,Neurod4tm1Kag/Neurod4tm1Kag,Neurog2tm1Fgu/Neurog2tm1Fgu
Genetic Background: involves: 129/Sv * C57BL/6 * CBA * ICR

Allelic Composition: Ascl1tm1And/Ascl1tm1And,Neurod1tm1Jle/Neurod1tm1Jle,Neurod4tm1Kag/Neurod4tm1Kag
Genetic Background: involves: 129/Sv * C57BL/6 * CBA * ICR

 MP:0003728 abnormal photoreceptor layer "malformation/anomalous structure of the photoreceptor layer" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Neurod1tm1Jle/Neurod1tm1Jle,Neurod4tm1Kag/Neurod4tm1Kag,Neurog2tm1Fgu/Neurog2tm1Fgu
Genetic Background: involves: 129/Sv * C57BL/6 * CBA * ICR

 MP:0003731 abnormal outer nuclear layer morphology "malformation/anomalous structure of the retinal layer that contains the nuclei and cell bodies of rods and cones" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Neurod1tm1Jle/Neurod1tm1Jle,Neurod4tm1Kag/Neurod4tm1Kag,Neurog2tm1Fgu/Neurog2tm1Fgu
Genetic Background: involves: 129/Sv * C57BL/6 * CBA * ICR

 MP:0003733 abnormal inner nuclear layer morphology "malformation/anomalous structure of the retinal layer which contains the cell bodies of bipolar, horizontal, and amacrine cells" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Neurod1tm1Jle/Neurod1tm1Jle,Neurod4tm1Kag/Neurod4tm1Kag,Neurog2tm1Fgu/Neurog2tm1Fgu
Genetic Background: involves: 129/Sv * C57BL/6 * CBA * ICR

Allelic Composition: Ascl1tm1And/Ascl1tm1And,Neurod4tm1Kag/Neurod4tm1Kag,Neurog2tm1Fgu/Neurog2tm1Fgu
Genetic Background: involves: 129/Sv * C57BL/6 * CBA * ICR

Allelic Composition: Ascl1tm1And/Ascl1tm1And,Neurod1tm1Jle/Neurod1tm1Jle,Neurod4tm1Kag/Neurod4tm1Kag
Genetic Background: involves: 129/Sv * C57BL/6 * CBA * ICR

 MP:0005241 abnormal retinal ganglion layer morphology "anomalous structure of the innermost nuclear layer of the retina, which projects axons through the optic nerve to the brain " [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Wnt9bclf1/Wnt9bclf1,clf2/clf2+
Genetic Background: AEJ.A/Jur

 MP:0005547 abnormal Muller cell morphology "anomalous structure of the elongated neuroglial cells that traverse all the layers of the retina and that act as supporting elements" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Neurod1tm1Jle/Neurod1tm1Jle,Neurod4tm1Kag/Neurod4tm1Kag
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6 * CBA * ICR

Allelic Composition: Ascl1tm1And/Ascl1tm1And,Neurod4tm1Kag/Neurod4tm1Kag
Genetic Background: either: (involves: 129S2/SvPas * C57BL/6 * CBA) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA)

Allelic Composition: Neurod1tm1Jle/Neurod1tm1Jle,Neurod4tm1Kag/Neurod4tm1Kag,Neurog2tm1Fgu/Neurog2tm1Fgu
Genetic Background: involves: 129/Sv * C57BL/6 * CBA * ICR

Allelic Composition: Ascl1tm1And/Ascl1tm1And,Neurod4tm1Kag/Neurod4tm1Kag,Neurog2tm1Fgu/Neurog2tm1Fgu
Genetic Background: involves: 129/Sv * C57BL/6 * CBA * ICR

Allelic Composition: Ascl1tm1And/Ascl1tm1And,Neurod1tm1Jle/Neurod1tm1Jle,Neurod4tm1Kag/Neurod4tm1Kag
Genetic Background: involves: 129/Sv * C57BL/6 * CBA * ICR

 MP:0006068 abnormal horizontal cell morphology "anomalous structure of the laterally interconnecting neurons in the outer plexiform layer" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Neurod1tm1Jle/Neurod1tm1Jle,Neurod4tm1Kag/Neurod4tm1Kag,Neurog2tm1Fgu/Neurog2tm1Fgu
Genetic Background: involves: 129/Sv * C57BL/6 * CBA * ICR

Allelic Composition: Ascl1tm1And/Ascl1tm1And,Neurod4tm1Kag/Neurod4tm1Kag,Neurog2tm1Fgu/Neurog2tm1Fgu
Genetic Background: involves: 129/Sv * C57BL/6 * CBA * ICR

 MP:0006069 abnormal retinal neuronal layer morphology "malformation in any of the neuronal layers that make up the retina, including the ganglion cell, inner plexiform, inner nuclear, outer plexiform, outer nuclear layers, the inner and outer segments" [smb:Susan M Bello, Mouse Genome Informatics Curator, Gray s Anatomy:ISBN 0-914294-08-3]
Show

Allelic Composition: Neurod1tm1Jle/Neurod1tm1Jle,Neurod4tm1Kag/Neurod4tm1Kag,Neurog2tm1Fgu/Neurog2tm1Fgu
Genetic Background: involves: 129/Sv * C57BL/6 * CBA * ICR

 MP:0006073 abnormal retinal bipolar cell morphology "anomalous structure of the cells that transmit signals from the photoreceptors to retinal amacrine and ganglion cells" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:92623:]
Show

Allelic Composition: Neurod1tm1Jle/Neurod1tm1Jle,Neurod4tm1Kag/Neurod4tm1Kag,Neurog2tm1Fgu/Neurog2tm1Fgu
Genetic Background: involves: 129/Sv * C57BL/6 * CBA * ICR

Allelic Composition: Ascl1tm1And/Ascl1tm1And,Neurod4tm1Kag/Neurod4tm1Kag,Neurog2tm1Fgu/Neurog2tm1Fgu
Genetic Background: involves: 129/Sv * C57BL/6 * CBA * ICR

Allelic Composition: Ascl1tm1And/Ascl1tm1And,Neurod1tm1Jle/Neurod1tm1Jle,Neurod4tm1Kag/Neurod4tm1Kag
Genetic Background: involves: 129/Sv * C57BL/6 * CBA * ICR

 MP:0006095 absent amacrine cells "absence or loss of the amacrine cells, which constitute one of the three types of interneurons found in the inner nuclear layer of the mature retina" [smb:Susan M Bello, Mouse Genome Informatics Curator, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:74753]
Show

Allelic Composition: Neurod1tm1Jle/Neurod1tm1Jle,Neurod4tm1Kag/Neurod4tm1Kag
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6 * CBA * ICR

 MP:0006096 absent retinal bipolar cells "absence of the cells that transmit signals from the photoreceptors to retinal amacrine and ganglion cells" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, smb:Susan M Bello, Mouse Genome Informatics Curator, J:65410]
Show

Allelic Composition: Ascl1tm1And/Ascl1tm1And,Neurod4tm1Kag/Neurod4tm1Kag
Genetic Background: either: (involves: 129S2/SvPas * C57BL/6 * CBA) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA)

 MP:0006097 abnormal cerebellar lobule formation "anomaly in the formation of the lobes of the cerebellum" [smb:Susan M Bello, Mouse Genome Informatics Curator, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:65410]
Show

Allelic Composition: Wnt9bclf1/Wnt9bclf1,clf2/clf2+
Genetic Background: AEJ.A/Jur

 MP:0006098 absent cerebellar lobules "missing lobes of the cerebellum" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Wnt9bclf1/Wnt9bclf1,clf2/clf2+
Genetic Background: AEJ.A/Jur

 MP:0006099 thin granule layer "reduced thickness of the innermost cortical layer of the cerebellum that contains granule cells" [smb:Susan M Bello, Mouse Genome Informatics Curator, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:65410]
Show

Allelic Composition: Wnt9bclf1/Wnt9bclf1,clf2/clf2+
Genetic Background: AEJ.A/Jur

 MP:0006104 abnormal tectum morphology "any structural alterations or malfunction of the rostral part of the midbrain roof" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, smb:Susan M Bello, Mouse Genome Informatics Curator, J:65762]
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Allelic Composition: Ascl1tm1And/Ascl1tm1And,Neurod4tm1Kag/Neurod4tm1Kag
Genetic Background: either: (involves: 129S2/SvPas * C57BL/6 * CBA) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA)

 MP:0006105 reduced tectum size "reduced size of the rostral part of the midbrain roof" [smb:Susan M Bello, Mouse Genome Informatics Curator, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:65410]
Show

Allelic Composition: Ascl1tm1And/Ascl1tm1And,Neurod4tm1Kag/Neurod4tm1Kag
Genetic Background: either: (involves: 129S2/SvPas * C57BL/6 * CBA) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA)

 MP:0006309 decreased retinal ganglion cell number "reduced number of ganglion neurons located in the innermost nuclear layer of the retina of that receive visual information from photoreceptors via various intermediate cells such as bipolar cells, amacrine cells, and horizontal cells; axons from these cells form the optic nerve and connect mainly to the lateral geniculate nucleus (LGN) and to the suprachiasmatic nucleus in the brain" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Neurod1tm1Jle/Neurod1tm1Jle,Neurod4tm1Kag/Neurod4tm1Kag,Neurog2tm1Fgu/Neurog2tm1Fgu
Genetic Background: involves: 129/Sv * C57BL/6 * CBA * ICR

 MP:0008106 decreased amacrine cell number "reduction in the number of one of the three types of interneurons found in the inner nuclear layer of the mature retina" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Neurod1tm1Jle/Neurod1tm1Jle,Neurod4tm1Kag/Neurod4tm1Kag,Neurog2tm1Fgu/Neurog2tm1Fgu
Genetic Background: involves: 129/Sv * C57BL/6 * CBA * ICR

Allelic Composition: Ascl1tm1And/Ascl1tm1And,Neurod4tm1Kag/Neurod4tm1Kag,Neurog2tm1Fgu/Neurog2tm1Fgu
Genetic Background: involves: 129/Sv * C57BL/6 * CBA * ICR

 MP:0008446 decreased retinal cone cell number "reduced number of one of the photoreceptor cell types in the retina, in which the photopigment is in invaginations of the cell membrane of the outer segment" [MESH:A08.663.650.650.670.100, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Neurod1tm1Jle/Neurod1tm1Jle,Neurod4tm1Kag/Neurod4tm1Kag,Neurog2tm1Fgu/Neurog2tm1Fgu
Genetic Background: involves: 129/Sv * C57BL/6 * CBA * ICR

 MP:0008511 thin retinal inner nuclear layer "reduced thickness of the retinal layer which contains the cell bodies of bipolar, horizontal, and amacrine cells" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Neurod1tm1Jle/Neurod1tm1Jle,Neurod4tm1Kag/Neurod4tm1Kag,Neurog2tm1Fgu/Neurog2tm1Fgu
Genetic Background: involves: 129/Sv * C57BL/6 * CBA * ICR

 MP:0008516 disorganized retinal outer nuclear layer "derangement of the normal pattern of the retinal layer that contains the nuclei and cell bodies of rods and cones" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Neurod1tm1Jle/Neurod1tm1Jle,Neurod4tm1Kag/Neurod4tm1Kag,Neurog2tm1Fgu/Neurog2tm1Fgu
Genetic Background: involves: 129/Sv * C57BL/6 * CBA * ICR

 MP:0009937 abnormal neuron differentiation "abnormal growth or development of the cells of the nervous system that receive, conduct, and transmit impulses" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Ascl1tm1And/Ascl1tm1And,Neurod4tm1Kag/Neurod4tm1Kag
Genetic Background: either: (involves: 129S2/SvPas * C57BL/6 * CBA) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA)

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
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Allelic Composition: Wnt9bclf1/Wnt9bclf1,clf2/clf2+
Genetic Background: AEJ.A/Jur

 MP:0011089 complete perinatal lethality "death of all organisms of a given genotype in a population within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]
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Allelic Composition: Neurod1tm1Jle/Neurod1tm1Jle,Neurod4tm1Kag/Neurod4tm1Kag
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6 * CBA * ICR

Allelic Composition: Neurod1tm1Jle/Neurod1tm1Jle,Neurod4tm1Kag/Neurod4tm1Kag,Neurog2tm1Fgu/Neurog2tm1Fgu
Genetic Background: involves: 129/Sv * C57BL/6 * CBA * ICR

Allelic Composition: Ascl1tm1And/Ascl1tm1And,Neurod4tm1Kag/Neurod4tm1Kag,Neurog2tm1Fgu/Neurog2tm1Fgu
Genetic Background: involves: 129/Sv * C57BL/6 * CBA * ICR

Allelic Composition: Ascl1tm1And/Ascl1tm1And,Neurod1tm1Jle/Neurod1tm1Jle,Neurod4tm1Kag/Neurod4tm1Kag
Genetic Background: involves: 129/Sv * C57BL/6 * CBA * ICR

Allelic Composition: Ascl1tm1And/Ascl1tm1And,Neurod4tm1Kag/Neurod4tm1Kag
Genetic Background: involves: 129/Sv * C57BL/6 * CBA * ICR

Allelic Composition: Neurod4tm1Kag/Neurod4tm1Kag,Neurog2tm1Fgu/Neurog2tm1Fgu
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * ICR

 MP:0011099 complete lethality throughout fetal growth and development "death of all organisms of a given genotype in a population between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith]
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Allelic Composition: Ascl1tm1And/Ascl1tm1And,Neurod4tm1Kag/Neurod4tm1Kag
Genetic Background: either: (involves: 129S2/SvPas * C57BL/6 * CBA) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA)

 MP:0030005 increased retinal apoptosis "increase in the number of cells in the retina undergoing programmed cell death" [MGI:anna]
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Allelic Composition: Neurod1tm1Jle/Neurod1tm1Jle,Neurod4tm1Kag/Neurod4tm1Kag,Neurog2tm1Fgu/Neurog2tm1Fgu
Genetic Background: involves: 129/Sv * C57BL/6 * CBA * ICR

Allelic Composition: Ascl1tm1And/Ascl1tm1And,Neurod1tm1Jle/Neurod1tm1Jle,Neurod4tm1Kag/Neurod4tm1Kag
Genetic Background: involves: 129/Sv * C57BL/6 * CBA * ICR

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
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The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr