ENSMUSG00000055421


Mus musculus

Features
Gene ID: ENSMUSG00000055421
  
Biological name :Pcdh9
  
Synonyms : Pcdh9 / protocadherin 9
  
Possible biological names infered from orthology : Q9HC56
  
Species: Mus musculus
  
Chr. number: 14
Strand: -1
Band: E2.1
Gene start: 93013410
Gene end: 93890679
  
Corresponding Affymetrix probe sets: 10421924 (MoGene1.0st)   10421932 (MoGene1.0st)   1429861_at (Mouse Genome 430 2.0 Array)   1442659_at (Mouse Genome 430 2.0 Array)   1458269_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000141205
Ensembl peptide - ENSMUSP00000141396
Ensembl peptide - ENSMUSP00000142260
Ensembl peptide - ENSMUSP00000142224
Ensembl peptide - ENSMUSP00000141759
Ensembl peptide - ENSMUSP00000141602
Ensembl peptide - ENSMUSP00000070935
NCBI entrez gene - 211712     See in Manteia.
MGI - MGI:1306801
RefSeq - XM_006518777
RefSeq - NM_001081377
RefSeq - NM_001271798
RefSeq - NM_001271799
RefSeq - NM_001271800
RefSeq - XM_006518774
RefSeq - XM_006518775
RefSeq - XM_006518776
RefSeq Peptide - NP_001333651
RefSeq Peptide - NP_001074846
RefSeq Peptide - NP_001258727
RefSeq Peptide - NP_001258728
RefSeq Peptide - NP_001258729
swissprot - A0A0A6YWY8
swissprot - A0A0A6YWM0
swissprot - A0A0A6YY37
swissprot - F8VPK8
swissprot - A0A0A6YVP5
swissprot - A0A0A6YY09
Ensembl - ENSMUSG00000055421
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pcdh9ENSDARG00000063264Danio rerio
 PCDH9ENSGALG00000016908Gallus gallus
 PCDH9ENSG00000184226Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pcdh11x / protocadherin 11 X-linked / Q9BZA7* / Q9BZA8* / PCDH11Y* / protocadherin 11 Y-linked*ENSMUSG0000003475555
Pcdh7 / protocadherin 7 / O60245*ENSMUSG0000002910837
Pcdh1 / protocadherin 1 / Q08174*ENSMUSG0000005137534
Pcdh20 / Q8BIZ0 / Protocadherin-20 / Q8N6Y1* / AL592490.1*ENSMUSG0000005050530
Pcdha6 / Q9UN73* / Q9Y5H6* / PCDHA8* / protocadherin alpha 6* / protocadherin alpha 8*ENSMUSG0000010370723
Pcdha11 / protocadherin alpha 11 / Q9Y5I1*ENSMUSG0000010220622
Q91Y13 / Pcdha7 / Protocadherin alpha-7 / Q9Y5H5* / PCDHA9* / Q9UN72* / protocadherin alpha 9*ENSMUSG0000010431822
Q91Y20 / Pcdha11 / protocadherin alpha 11ENSMUSG0000000744022
O88689 / Pcdha4 / Protocadherin alpha-4 / Q9UN74*ENSMUSG0000010425222
Pcdha9 / Q91Y11 / Protocadherin alpha-9 / Q9Y5I2* / PCDHA10* / protocadherin alpha 10*ENSMUSG0000010377022
Pcdha1 / protocadherin alpha 1 / Q9Y5I3*ENSMUSG0000010344222
Pcdha8 / protocadherin alpha 8 / Q9Y5H5* / PCDHA7* / PCDHA9* / Q9UN72* / protocadherin alpha 7* / protocadherin alpha 9*ENSMUSG0000010380022
Pcdha5 / protocadherin alpha 5 / Q9Y5H7*ENSMUSG0000010309222
Pcdha12 / protocadherin alpha 12 / Q9Y5I0* / PCDHA13* / protocadherin alpha 13*ENSMUSG0000010331022
Pcdh15 / Q99PJ1 / Protocadherin-15 / Q96QU1* / protocadherin related 15*ENSMUSG0000005261321
Pcdhga9ENSMUSG0000010244020
Pcdhgc3 / protocadherin gamma subfamily C, 3ENSMUSG0000010291819


Protein motifs (from Interpro)
Interpro ID Name
 IPR002126  Cadherin
 IPR013164  Cadherin, N-terminal
 IPR013585  Protocadherin
 IPR015919  Cadherin-like
 IPR020894  Cadherin conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules IEA
 biological_processGO:0008150 biological_process ND
 biological_processGO:0030900 forebrain development IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030426 growth cone IDA
 cellular_componentGO:0044291 cell-cell contact zone IDA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001399 hyperactivity "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]
Show

Allelic Composition: Spp1tm1.1Dhd/Spp1tm1.1Dhd
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001405 impaired coordination "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Spp1tm1.1Dhd/Spp1tm1.1Dhd
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002067 abnormal sensory capabilities/reflexes/nociception "inability or altered ability to respond to a sensory stimulus" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Spp1tm1.1Dhd/Spp1tm1.1Dhd
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002801 abnormal long-term recognition memory "defects in long-term memory for objects that is consolidated over hours and days after training." [CFG:Center for Functional Genomics , Northwestern University]
Show

Allelic Composition: Spp1tm1.1Dhd/Spp1tm1.1Dhd
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0006254 thin cerebral cortex "decreased depth of the mantle covering the surface of the cerebral hemispheres" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:84683]
Show

Allelic Composition: Spp1tm1.1Dhd/Spp1tm1.1Dhd
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Pcdh9tm1Mjhk/Pcdh9+
Genetic Background: B6.Cg-Pcdh9tm1Mjhk

 MP:0008143 abnormal dendrite morphology "any structural anomaly of the highly branched tree-like process of a neuron that serves as a receptive field and conducts impulses toward the cell body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Spp1tm1.1Dhd/Spp1tm1.1Dhd
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Pcdh9tm1Mjhk/Pcdh9+
Genetic Background: B6.Cg-Pcdh9tm1Mjhk

 MP:0008948 decreased neuron number "fewer than normal numbers of the cells of the nervous system that receive, conduct, and transmit impulses" [MESH:A08.663]
Show

Allelic Composition: Spp1tm1.1Dhd/Spp1tm1.1Dhd
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Pcdh9tm1Mjhk/Pcdh9+
Genetic Background: B6.Cg-Pcdh9tm1Mjhk

 MP:0009142 decreased prepulse inhibition "decrease in the ability of a relatively mild stimulus to suppress the response to a strong, startle-eliciting stimulus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Spp1tm1.1Dhd/Spp1tm1.1Dhd
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0009936 abnormal dendritic spine morphology "any structural anomaly of the small membranous protrusion from the dendrite of a neuron that is involved in synaptic transmission; it typically receives input from a single synapse of an axon" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Spp1tm1.1Dhd/Spp1tm1.1Dhd
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0020396 abnormal social recognition "any anomaly in the ability of an individual to recognize another individual of the same species during repeated encounters" [PMID:11950245]
Show

Allelic Composition: Spp1tm1.1Dhd/Spp1tm1.1Dhd
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Pcdh9tm1Mjhk/Pcdh9+
Genetic Background: B6.Cg-Pcdh9tm1Mjhk

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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