ENSMUSG00000103770


Mus musculus

Features
Gene ID: ENSMUSG00000103770
  
Biological name :Pcdha9
  
Synonyms : Pcdha9 / Protocadherin alpha-9 / Q91Y11
  
Possible biological names infered from orthology : PCDHA10 / protocadherin alpha 10 / Q9Y5I2
  
Species: Mus musculus
  
Chr. number: 18
Strand: 1
Band: B2
Gene start: 36997880
Gene end: 37187657
  
Corresponding Affymetrix probe sets: 1420798_s_at (Mouse Genome 430 2.0 Array)   1424341_s_at (Mouse Genome 430 2.0 Array)   1451769_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000111323
NCBI entrez gene - 192161     See in Manteia.
MGI - MGI:2447322
RefSeq - NM_138661
RefSeq Peptide - NP_619602
swissprot - Q91Y11
Ensembl - ENSMUSG00000103770
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pcdh1a3ENSDARG00000104598Danio rerio
 pcdh1a3ENSDARG00000103602Danio rerio
 pcdh1g9ENSDARG00000057519Danio rerio
 pcdh2aa1ENSDARG00000037695Danio rerio
 pcdh2aa15ENSDARG00000088136Danio rerio
 pcdh2ab1ENSDARG00000071904Danio rerio
 pcdh2ab1ENSDARG00000089874Danio rerio
 pcdh2ab12ENSDARG00000104080Danio rerio
 pcdh2ab2ENSDARG00000099468Danio rerio
 pcdh2ab2ENSDARG00000037691Danio rerio
 pcdh2ab3ENSDARG00000102719Danio rerio
 pcdh2ab6ENSDARG00000091043Danio rerio
 si:ch73-379j16.2ENSDARG00000099535Danio rerio
 si:dkey-262j3.7ENSDARG00000104141Danio rerio
 si:dkeyp-115d7.2ENSDARG00000089297Danio rerio
 PCDHA2ENSGALG00000043142Gallus gallus
 Q9Y5I2ENSG00000250120Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pcdha6 / Q9UN73* / Q9Y5H6* / PCDHA8* / protocadherin alpha 6* / protocadherin alpha 8*ENSMUSG0000010370777
Pcdha8 / protocadherin alpha 8 / Q9Y5H5* / PCDHA7* / PCDHA9* / Q9UN72* / protocadherin alpha 7* / protocadherin alpha 9*ENSMUSG0000010380076
Pcdha1 / protocadherin alpha 1 / Q9Y5I3*ENSMUSG0000010344276
Q91Y13 / Pcdha7 / Protocadherin alpha-7 / Q9Y5H5* / PCDHA9* / Q9UN72* / protocadherin alpha 9*ENSMUSG0000010431875
O88689 / Pcdha4 / Protocadherin alpha-4 / Q9UN74*ENSMUSG0000010425275
Pcdha11 / protocadherin alpha 11 / Q9Y5I1*ENSMUSG0000010220675
Pcdha12 / protocadherin alpha 12 / Q9Y5I0* / PCDHA13* / protocadherin alpha 13*ENSMUSG0000010331075
Q91Y20 / Pcdha11 / protocadherin alpha 11ENSMUSG0000000744075
Pcdha5 / protocadherin alpha 5 / Q9Y5H7*ENSMUSG0000010309274
Pcdhgc3 / protocadherin gamma subfamily C, 3ENSMUSG0000010291835
Pcdhga9ENSMUSG0000010244034
Pcdh7 / protocadherin 7 / O60245*ENSMUSG0000002910830
Pcdh9 / protocadherin 9 / Q9HC56*ENSMUSG0000005542128
Pcdh11x / protocadherin 11 X-linked / Q9BZA7* / Q9BZA8* / PCDH11Y* / protocadherin 11 Y-linked*ENSMUSG0000003475528
Pcdh1 / protocadherin 1 / Q08174*ENSMUSG0000005137527
Pcdh15 / Q99PJ1 / Protocadherin-15 / Q96QU1* / protocadherin related 15*ENSMUSG0000005261326
Pcdh20 / Q8BIZ0 / Protocadherin-20 / Q8N6Y1* / AL592490.1*ENSMUSG0000005050523


Protein motifs (from Interpro)
Interpro ID Name
 IPR002126  Cadherin
 IPR013164  Cadherin, N-terminal
 IPR015919  Cadherin-like
 IPR020894  Cadherin conserved site
 IPR031904  Cadherin, C-terminal catenin-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IBA
 biological_processGO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules IEA
 biological_processGO:0007267 cell-cell signaling IBA
 biological_processGO:0007399 nervous system development IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000284 double outlet right ventricle "both the aorta and the pulmonary trunk originate from the right ventricle, usually in conjunction with a ventricular septal defect" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:67826]
Show

Allelic Composition: Tet1tuft/Tet1tuft
Genetic Background: involves: 3H1/Lznf * M. m. castaneus

 MP:0000286 abnormal mitral valve morphology "malformation of the valve between the left atrium and the left ventricle of the heart" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370]
Show

Allelic Composition: Tet1tuft/Tet1tuft
Genetic Background: involves: 3H1/Lznf * M. m. castaneus

 MP:0001625 cardiac hypertrophy "an increase in size of the cardiac tissue, not due to increased cell number " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Pax3Rwa/Pax3Rwa
Genetic Background: B6N.Cg-Pax3Rwa

 MP:0003393 decreased cardiac output "reduction in the blood volume pumped by each ventricle per minute" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Pcdha9em1Clo/Pcdha9em1Clo,Sap130em1Clo/Sap130em1Clo
Genetic Background: C57BL/6J-Sap130em1Clo Pcdha9em1Clo/MurrJ

 MP:0010463 aorta stenosis "diffuse constriction or narrowing of the aorta" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Pax3Rwa/Pax3Rwa
Genetic Background: B6N.Cg-Pax3Rwa

Allelic Composition: Pcdha9b2b635.1Clo/Pcdha9b2b635.1Clo,Sap130b2b635.2Clo/Sap130+
Genetic Background: C57BL/6J-Sap130b2b635.2Clo Pcdha9b2b635.1Clo

 MP:0010484 bicuspid aortic valve "the presence of two cusps in the aortic valve instead of three" [http://emedicine.medscape.com]
Show

Allelic Composition: Pax3Rwa/Pax3Rwa
Genetic Background: B6N.Cg-Pax3Rwa

 MP:0010541 aorta hypoplasia "underdevelopment or reduced size of the main trunk of the systemic arterial system that originates from the base of the left ventricle of the heart and extends to the abdomen at the point where it branches into the common iliac arteries, usually due to reduced cell number" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Pax3Rwa/Pax3Rwa
Genetic Background: B6N.Cg-Pax3Rwa

Allelic Composition: Pcdha9em1Clo/Pcdha9em1Clo,Sap130em1Clo/Sap130em1Clo
Genetic Background: C57BL/6J-Sap130em1Clo Pcdha9em1Clo/MurrJ

 MP:0010580 decreased heart left ventricle size "less than average size of the left ventricle compared to the average for a particular population" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Pcdha9em1Clo/Pcdha9em1Clo,Sap130em1Clo/Sap130em1Clo
Genetic Background: C57BL/6J-Sap130em1Clo Pcdha9em1Clo/MurrJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr