ENSDARG00000005150


Danio rerio

Features
Gene ID: ENSDARG00000005150
  
Biological name :tbx20
  
Synonyms : Q9I9K7 / T-box 20 / tbx20
  
Possible biological names infered from orthology : Q9ES03 / Q9UMR3 / T-box transcription factor TBX20
  
Species: Danio rerio
  
Chr. number: 16
Strand: -1
Band:
Gene start: 42509011
Gene end: 42523744
  
Corresponding Affymetrix probe sets: Dr.8231.1.S1_at (Zebrafish Array)   NM_131506_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000026669
NCBI entrez gene - 57936     See in Manteia.
RefSeq - NM_131506
RefSeq Peptide - NP_571581
swissprot - B3DJG4
swissprot - Q9I9K7
ZFIN ID - ZDB-GENE-000427-7
Ensembl - ENSDARG00000005150
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TBX20ENSGALG00000032097Gallus gallus
 TBX20ENSG00000164532Homo sapiens
 Tbx20ENSMUSG00000031965Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
tbx15 / T-box 15 / O70306* / Q96SF7* / T-box transcription factor TBX15 *ENSDARG0000000258238
tbx18 / T-box 18 / O95935*ENSDARG0000003693036
tbx2b / Q7ZTU9 / T-box 2b / TBX2* / Q60707* / Q13207* / T-box 2* / T-box transcription factor TBX2 *ENSDARG0000000612034
tbx3a / T-box 3a / TBX3* / O15119* / P70324* / T-box 3*ENSDARG0000000221633
tbx2a / T-box 2a / TBX2* / Q60707* / Q13207* / T-box 2* / T-box transcription factor TBX2 *ENSDARG0000001802533
tbx1 / Q8AXX2 / T-box 1 / O43435*ENSDARG0000003189132
tbx5a / Q9IAK8 / T-box 5a / TBX5* / Q99593* / P70326* / T-box 5*ENSDARG0000002489430
tbx3b / T-box 3bENSDARG0000006150928
tbx4 / T-box 4 / P57082* / P70325*ENSDARG0000003005828
tbx22 / T-box 22 / Q8K402* / Q9Y458*ENSDARG0000009174827
tbx5b / T-box 5b / TBX5* / P70326* / Q99593* / T-box 5*ENSDARG0000009206026
tbx16 / T-box 16ENSDARG0000000732926
tbx6 / Q8JIS6 / T-box 6 / P70327* / O95947* / T-box transcription factor TBX6 *ENSDARG0000001178525


Protein motifs (from Interpro)
Interpro ID Name
 IPR001699  Transcription factor, T-box
 IPR008967  p53-like transcription factor, DNA-binding
 IPR018186  Transcription factor, T-box, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001568 blood vessel development IMP
 biological_processGO:0001570 vasculogenesis IMP
 biological_processGO:0001947 heart looping IMP
 biological_processGO:0003313 heart rudiment development IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007507 heart development IMP
 biological_processGO:0035050 embryonic heart tube development IMP
 biological_processGO:0035162 embryonic hemopoiesis IMP
 biological_processGO:0035844 cloaca development IMP
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IMP
 biological_processGO:0060038 cardiac muscle cell proliferation IMP
 biological_processGO:0060043 regulation of cardiac muscle cell proliferation IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000007 blood blood accumulation sinus venosus , abnormal
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 ZFA:0000009 cardiac ventricle cardiac ventricle contractility , abnormal
cardiac ventricle decreased strength , abnormal
cardiac ventricle decreased size , abnormal
cardiac ventricle cardiac muscle cell proliferation decreased process quality , abnormal
cardiac ventricle cardiac muscle cell decreased amount , abnormal
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 ZFA:0000028 heart primordium heart primordium hypoplastic , abnormal
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 ZFA:0000029 hindbrain hindbrain decreased amount , abnormal
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 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000114 heart heart quality , abnormal
heart decreased contractility , abnormal
heart decreased amount , abnormal
heart distended , abnormal
heart decreased size , abnormal
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 ZFA:0000118 hypophysis hypophysis decreased amount , abnormal
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 ZFA:0000360 heart tube heart tube morphology , abnormal
heart tube decreased size , abnormal
heart tube decreased amount , abnormal
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 ZFA:0001094 whole organism whole organism dead , abnormal
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 ZFA:0001285 intersegmental vessel intersegmental vessel aplastic , abnormal
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 ZFA:0005024 trunk vasculature trunk vasculature morphology , abnormal
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 ZFA:0005041 anterior lateral plate mesoderm anterior lateral plate mesoderm heart primordium decreased amount , abnormal
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 ZFA:0005061 ventricular myocardium ventricular myocardium decreased thickness , abnormal
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 ZFA:0005077 vascular cord vascular cord morphology , abnormal
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 ZFA:0005731 branchiomotor neuron branchiomotor neuron decreased amount , abnormal
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 ZFA:0005781 cloaca cloaca morphology , abnormal
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 ZFA:0009316 cardiac muscle cell cardiac muscle cell decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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