ENSDARG00000030058


Danio rerio

Features
Gene ID: ENSDARG00000030058
  
Biological name :tbx4
  
Synonyms : T-box 4 / tbx4
  
Possible biological names infered from orthology : P57082 / P70325
  
Species: Danio rerio
  
Chr. number: 15
Strand: 1
Band:
Gene start: 27384798
Gene end: 27411695
  
Corresponding Affymetrix probe sets: Dr.8234.1.S1_at (Zebrafish Array)   NM_130914_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000010616
Ensembl peptide - ENSDARP00000138962
NCBI entrez gene - 30070     See in Manteia.
RefSeq - NM_130914
RefSeq Peptide - NP_570989
swissprot - F1R688
swissprot - A0A0R4ITJ0
ZFIN ID - ZDB-GENE-991124-5
Ensembl - ENSDARG00000030058
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TBX4ENSGALG00000005285Gallus gallus
 TBX4ENSG00000121075Homo sapiens
 Tbx4ENSMUSG00000000094Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
tbx5a / Q9IAK8 / T-box 5a / TBX5* / Q99593* / P70326* / T-box 5*ENSDARG0000002489446
tbx5b / T-box 5b / TBX5* / P70326* / Q99593* / T-box 5*ENSDARG0000009206039
tbx2a / T-box 2a / TBX2* / Q60707* / Q13207* / T-box 2* / T-box transcription factor TBX2 *ENSDARG0000001802529
tbx2b / Q7ZTU9 / T-box 2b / TBX2* / Q60707* / Q13207* / T-box 2* / T-box transcription factor TBX2 *ENSDARG0000000612028
tbx3a / T-box 3a / TBX3* / O15119* / P70324* / T-box 3*ENSDARG0000000221628
tbx15 / T-box 15 / O70306* / Q96SF7* / T-box transcription factor TBX15 *ENSDARG0000000258227
tbx1 / Q8AXX2 / T-box 1 / O43435*ENSDARG0000003189126
tbx18 / T-box 18 / O95935*ENSDARG0000003693024
tbx3b / T-box 3bENSDARG0000006150924
tbx20 / Q9I9K7 / T-box 20 / Q9UMR3* / Q9ES03* / T-box transcription factor TBX20 *ENSDARG0000000515023
tbx16 / T-box 16ENSDARG0000000732923
tbx6 / Q8JIS6 / T-box 6 / P70327* / O95947* / T-box transcription factor TBX6 *ENSDARG0000001178521
tbx22 / T-box 22 / Q8K402* / Q9Y458*ENSDARG0000009174819


Protein motifs (from Interpro)
Interpro ID Name
 IPR001699  Transcription factor, T-box
 IPR008967  p53-like transcription factor, DNA-binding
 IPR018186  Transcription factor, T-box, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0033340 pelvic fin development IMP
 biological_processGO:0035116 embryonic hindlimb morphogenesis IMP
 biological_processGO:0035119 embryonic pelvic fin morphogenesis IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001094 whole organism whole organism lacks all parts of type pelvic fin , abnormal
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 ZFA:0001184 pelvic fin pelvic fin absent , abnormal
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 ZFA:0001384 pelvic fin bud pelvic fin bud lacks all parts of type apical ectodermal ridge pelvic fin bud , abnormal
pelvic fin bud apical ectodermal ridge formation arrested , abnormal
pelvic fin bud mesenchyme absent , abnormal
pelvic fin bud mesenchyme increased distribution , abnormal
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 ZFA:0001385 apical ectodermal ridge pelvic fin bud apical ectodermal ridge pelvic fin bud absent , abnormal
Show

 ZFA:0001386 mesoderm pelvic fin bud mesoderm pelvic fin bud present , abnormal
Show

 ZFA:0001387 pelvic fin skeleton pelvic fin skeleton absent , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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