ENSDARG00000095019


Danio rerio

Features
Gene ID: ENSDARG00000095019
  
Biological name :lmo2
  
Synonyms : LIM domain only 2 (rhombotin-like 1) / lmo2 / Q9PTJ3
  
Possible biological names infered from orthology : LIM domain only 2 / P25791 / P25801 / Rhombotin-2
  
Species: Danio rerio
  
Chr. number: 18
Strand: 1
Band:
Gene start: 38288877
Gene end: 38296665
  
Corresponding Affymetrix probe sets: Dr.8065.1.S1_at (Zebrafish Array)   NM_131111_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000115969
NCBI entrez gene - 30332     See in Manteia.
RefSeq - NM_131111
RefSeq Peptide - NP_571186
swissprot - Q9PTJ3
ZFIN ID - ZDB-GENE-980526-419
Ensembl - ENSDARG00000095019
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LMO2ENSGALG00000029892Gallus gallus
 LMO2ENSG00000135363Homo sapiens
 Lmo2ENSMUSG00000032698Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
lmo1 / Q8JFQ2 / LIM domain only 1ENSDARG0000003450448
lmo3 / Q503U0 / LIM domain only 3 / Q8TAP4* / Q8BZL8* / Mus musculus LIM domain only 3 (Lmo3), transcript variant 2, mRNA.*ENSDARG0000000872045
lmo4b / LIM domain only 4b / LMO4* / P61968* / P61969* / LIM domain only 4* / LIM domain transcription factor LMO4 *ENSDARG0000005474938
si:dkey-90l8.3ENSDARG0000010367638
lmo4a / LIM domain only 4aENSDARG0000001385337
zgc:56628ENSDARG0000011002033
lhx2a / LIM homeobox 2aENSDARG0000003796431
lhx9 / Q1LWV4 / LIM homeobox 9 / Q9WUH2* / Q9NQ69* / LIM/homeobox protein Lhx9 *ENSDARG0000005697931
lmx1al / LIM homeobox transcription factor 1, alpha-likeENSDARG0000007791531
lhx2b / LIM homeobox 2bENSDARG0000003122230
lmx1bb / LIM homeobox transcription factor 1, beta b / LMX1B* / O60663* / LIM homeobox transcription factor 1 beta*ENSDARG0000006836529
isl2a / P53406 / ISL LIM homeobox 2a / ISL2* / Q96A47* / ISL LIM homeobox 2*ENSDARG0000000397128
lmx1ba / LIM homeobox transcription factor 1, beta a / LMX1B* / O60663* / LIM homeobox transcription factor 1 beta*ENSDARG0000010481528
lhx6 / LIM homeobox 6 / Q9R1R0* / Q9UPM6* / Mus musculus LIM homeobox protein 6 (Lhx6), transcript variant 5, mRNA.*ENSDARG0000000689628
isl1 / P53405 / ISL LIM homeobox 1 / P61371* / P61372* / Insulin enhancer protein ISL-1 *ENSDARG0000000402328
lhx4 / LIM homeobox 4 / P53776* / Q969G2* / LIM/homeobox protein Lhx4 *ENSDARG0000003945827
isl2b / P53407 / ISL LIM homeobox 2b / ISL2* / Q9CXV0* / Q96A47* / ISL LIM homeobox 2* / Insulin enhancer protein ISL-2 *ENSDARG0000005349927
LHX3 / LIM homeobox 3 / Q9UBR4*ENSDARG0000000380327
lhx8a / LIM homeobox 8a / LHX8* / O35652* / Q68G74* / LIM homeobox 8* / LIM/homeobox protein Lhx8 *ENSDARG0000000233026
lhx5 / P52889 / LIM homeobox 5 / Q9H2C1* / P61375* / LIM homeobox protein 5*ENSDARG0000005793626


Protein motifs (from Interpro)
Interpro ID Name
 IPR001781  Zinc finger, LIM-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001568 blood vessel development IMP
 biological_processGO:0001935 endothelial cell proliferation IMP
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0030097 hemopoiesis IMP
 biological_processGO:0030218 erythrocyte differentiation IGI
 biological_processGO:0031101 fin regeneration IMP
 biological_processGO:0035162 embryonic hemopoiesis IMP
 biological_processGO:0048821 erythrocyte development IMP
 biological_processGO:0061304 retinal blood vessel morphogenesis IMP
 cellular_componentGO:0005634 nucleus ISS
 molecular_functionGO:0003677 DNA binding ISS
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
RUNX1 regulates transcription of genes involved in differentiation of HSCs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain hemorrhagic , abnormal
Show

 ZFA:0000107 eye eye edematous , abnormal
Show

 ZFA:0001094 whole organism whole organism lacks all parts of type nucleate erythrocyte , abnormal
Show

 ZFA:0001114 head head edematous , abnormal
head increased size , abnormal
Show

 ZFA:0001115 trunk trunk intersegmental vessel morphology , abnormal
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 ZFA:0001261 ventricular system ventricular system edematous , abnormal
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 ZFA:0001269 regenerating fin regenerating fin decreased size , abnormal
regenerating fin vasculature decreased length , abnormal
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 ZFA:0001284 optic fissure optic fissure increased width , abnormal
optic fissure malformed , abnormal
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 ZFA:0005045 hyaloid artery hyaloid artery constricted , abnormal
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 ZFA:0005047 hyaloid vein hyaloid vein dilated , abnormal
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 ZFA:0005314 blood vessel blood vessel morphology , abnormal
Show

 ZFA:0007057 ocular blood vessel ocular blood vessel decreased diameter , abnormal
ocular blood vessel dilated , abnormal
ocular blood vessel increased permeability , abnormal
ocular blood vessel increased diameter , abnormal
Show

 ZFA:0009256 nucleate erythrocyte nucleate erythrocyte absent , abnormal
nucleate erythrocyte decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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