ENSG00000117036


Homo sapiens

Features
Gene ID: ENSG00000117036
  
Biological name :ETV3
  
Synonyms : ETS variant 3 / ETV3 / P41162
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q23.1
Gene start: 157121191
Gene end: 157138474
  
Corresponding Affymetrix probe sets: 1552423_at (Human Genome U133 Plus 2.0 Array)   214480_at (Human Genome U133 Plus 2.0 Array)   227200_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000327316
Ensembl peptide - ENSP00000357175
NCBI entrez gene - 2117     See in Manteia.
OMIM - 164873
RefSeq - XM_006711210
RefSeq - NM_001145312
RefSeq - NM_005240
RefSeq Peptide - NP_005231
RefSeq Peptide - NP_001138784
swissprot - P41162
Ensembl - ENSG00000117036
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000027138Gallus gallus
 ENSGALG00000000669Gallus gallus
 Etv3ENSMUSG00000003382Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ERF / P50548 / ETS2 repressor factorENSG0000010572247
ETV3L / Q6ZN32 / ETS variant 3 likeENSG0000025383132
AC010616.1ENSG0000026804126
ELK1 / P19419 / ELK1, ETS transcription factorENSG0000012676719
ELK4 / P28324 / ELK4, ETS transcription factorENSG0000015871118
ELK3 / P41970 / ELK3, ETS transcription factorENSG0000011114516
FEV / Q99581 / FEV, ETS transcription factorENSG0000016349715
FLI1 / Q01543 / Fli-1 proto-oncogene, ETS transcription factorENSG0000015170215
ERG / P11308 / ERG, ETS transcription factorENSG0000015755414
ETV4 / P43268 / ETS variant 4ENSG0000017583213
ETV1 / P50549 / ETS variant 1ENSG0000000646812
ETS1 / P14921 / ETS proto-oncogene 1, transcription factorENSG0000013495412
ETS2 / P15036 / ETS proto-oncogene 2, transcription factorENSG0000015755712
GABPA / Q06546 / GA binding protein transcription factor alpha subunitENSG0000015472712
ETV2 / O00321 / ETS variant 2ENSG0000010567211
ETV5 / P41161 / ETS variant 5ENSG0000024440511


Protein motifs (from Interpro)
Interpro ID Name
 IPR000418  Ets domain
 IPR032929  ETS translocation variant 3
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0008150 biological_process ND
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus IEA
 cellular_componentGO:0000790 nuclear chromatin IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0017053 transcriptional repressor complex IEA
 cellular_componentGO:0090571 RNA polymerase II transcription repressor complex IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0017151 DEAD/H-box RNA helicase binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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