ENSG00000163497


Homo sapiens

Features
Gene ID: ENSG00000163497
  
Biological name :FEV
  
Synonyms : FEV / FEV, ETS transcription factor / Q99581
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: q35
Gene start: 218981087
Gene end: 218985657
  
Corresponding Affymetrix probe sets: 207260_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000295727
NCBI entrez gene - 54738     See in Manteia.
OMIM - 607150
RefSeq - NM_017521
RefSeq Peptide - NP_059991
swissprot - Q99581
Ensembl - ENSG00000163497
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FevENSMUSG00000055197Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FLI1 / Q01543 / Fli-1 proto-oncogene, ETS transcription factorENSG0000015170252
ERG / P11308 / ERG, ETS transcription factorENSG0000015755449
ETS1 / P14921 / ETS proto-oncogene 1, transcription factorENSG0000013495433
ERF / P50548 / ETS2 repressor factorENSG0000010572232
ETS2 / P15036 / ETS proto-oncogene 2, transcription factorENSG0000015755732
ETV3 / P41162 / ETS variant 3ENSG0000011703632
GABPA / Q06546 / GA binding protein transcription factor alpha subunitENSG0000015472731
ETV5 / P41161 / ETS variant 5ENSG0000024440529
ELK1 / P19419 / ELK1, ETS transcription factorENSG0000012676729
ETV3L / Q6ZN32 / ETS variant 3 likeENSG0000025383129
AC010616.1ENSG0000026804128
ELK3 / P41970 / ELK3, ETS transcription factorENSG0000011114528
ETV4 / P43268 / ETS variant 4ENSG0000017583228
ETV2 / O00321 / ETS variant 2ENSG0000010567227
ELK4 / P28324 / ELK4, ETS transcription factorENSG0000015871126
ETV1 / P50549 / ETS variant 1ENSG0000000646826


Protein motifs (from Interpro)
Interpro ID Name
 IPR000418  Ets domain
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0042551 neuron maturation IEA
 biological_processGO:0048665 neuron fate specification IEA
 biological_processGO:1903507 negative regulation of nucleic acid-templated transcription IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0016607 nuclear speck IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity TAS
 molecular_functionGO:0003714 transcription corepressor activity TAS
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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