ENSG00000105672


Homo sapiens

Features
Gene ID: ENSG00000105672
  
Biological name :ETV2
  
Synonyms : ETS variant 2 / ETV2 / O00321
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: q13.12
Gene start: 35641745
Gene end: 35644871
  
Corresponding Affymetrix probe sets: 215510_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000475089
Ensembl peptide - ENSP00000468453
Ensembl peptide - ENSP00000477924
Ensembl peptide - ENSP00000480641
Ensembl peptide - ENSP00000368309
Ensembl peptide - ENSP00000368312
Ensembl peptide - ENSP00000384524
Ensembl peptide - ENSP00000385369
NCBI entrez gene - 2116     See in Manteia.
OMIM - 609358
RefSeq - XM_017026472
RefSeq - NM_001300974
RefSeq - NM_001304549
RefSeq - NM_014209
RefSeq - XM_005258652
RefSeq - XM_011526624
RefSeq Peptide - NP_001287903
RefSeq Peptide - NP_001291478
RefSeq Peptide - NP_055024
swissprot - O00321
swissprot - A0A087WX03
swissprot - K7ERX2
swissprot - Q3KNT2
swissprot - S4R454
swissprot - A0A087WTJ5
Ensembl - ENSG00000105672
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 etv2ENSDARG00000053868Danio rerio
 Etv2ENSMUSG00000006311Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ETS2 / P15036 / ETS proto-oncogene 2, transcription factorENSG0000015755727
FLI1 / Q01543 / Fli-1 proto-oncogene, ETS transcription factorENSG0000015170227
ETS1 / P14921 / ETS proto-oncogene 1, transcription factorENSG0000013495425
ERG / P11308 / ERG, ETS transcription factorENSG0000015755425
GABPA / Q06546 / GA binding protein transcription factor alpha subunitENSG0000015472723
ETV4 / P43268 / ETS variant 4ENSG0000017583222
ETV5 / P41161 / ETS variant 5ENSG0000024440522
ETV1 / P50549 / ETS variant 1ENSG0000000646821
FEV / Q99581 / FEV, ETS transcription factorENSG0000016349719
AC010616.1ENSG0000026804117
ETV3L / Q6ZN32 / ETS variant 3 likeENSG0000025383117
ETV3 / P41162 / ETS variant 3ENSG0000011703617
ERF / P50548 / ETS2 repressor factorENSG0000010572216
ELK1 / P19419 / ELK1, ETS transcription factorENSG0000012676714
ELK4 / P28324 / ELK4, ETS transcription factorENSG0000015871113
ELK3 / P41970 / ELK3, ETS transcription factorENSG0000011114513


Protein motifs (from Interpro)
Interpro ID Name
 IPR000418  Ets domain
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0001707 mesoderm formation IEA
 biological_processGO:0001824 blastocyst development IEA
 biological_processGO:0001890 placenta development IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007219 Notch signaling pathway IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0030097 hemopoiesis IEA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030218 erythrocyte differentiation IEA
 biological_processGO:0045603 positive regulation of endothelial cell differentiation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048514 blood vessel morphogenesis IEA
 biological_processGO:0060803 BMP signaling pathway involved in mesodermal cell fate specification IEA
 biological_processGO:2000382 positive regulation of mesoderm development IEA
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr