ENSG00000244405


Homo sapiens

Features
Gene ID: ENSG00000244405
  
Biological name :ETV5
  
Synonyms : ETS variant 5 / ETV5 / P41161
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: q27.2
Gene start: 186046308
Gene end: 186110318
  
Corresponding Affymetrix probe sets: 203348_s_at (Human Genome U133 Plus 2.0 Array)   203349_s_at (Human Genome U133 Plus 2.0 Array)   216375_s_at (Human Genome U133 Plus 2.0 Array)   230102_at (Human Genome U133 Plus 2.0 Array)   231083_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000388737
Ensembl peptide - ENSP00000413755
Ensembl peptide - ENSP00000412171
Ensembl peptide - ENSP00000405157
Ensembl peptide - ENSP00000399707
Ensembl peptide - ENSP00000389707
Ensembl peptide - ENSP00000306894
NCBI entrez gene - 2119     See in Manteia.
OMIM - 601600
RefSeq - NM_004454
RefSeq Peptide - NP_004445
swissprot - C9J0Z2
swissprot - H7C1D2
swissprot - C9JR66
swissprot - P41161
swissprot - C9JMF0
swissprot - C9J5A5
Ensembl - ENSG00000244405
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ETV5ENSGALG00000005768Gallus gallus
 Etv5ENSMUSG00000013089Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ETV1 / P50549 / ETS variant 1ENSG0000000646859
ETV4 / P43268 / ETS variant 4ENSG0000017583250
ETS1 / P14921 / ETS proto-oncogene 1, transcription factorENSG0000013495418
ETS2 / P15036 / ETS proto-oncogene 2, transcription factorENSG0000015755718
ERG / P11308 / ERG, ETS transcription factorENSG0000015755418
FLI1 / Q01543 / Fli-1 proto-oncogene, ETS transcription factorENSG0000015170217
GABPA / Q06546 / GA binding protein transcription factor alpha subunitENSG0000015472715
ETV2 / O00321 / ETS variant 2ENSG0000010567215
FEV / Q99581 / FEV, ETS transcription factorENSG0000016349713
ELK4 / P28324 / ELK4, ETS transcription factorENSG0000015871112
ELK1 / P19419 / ELK1, ETS transcription factorENSG0000012676712
ELK3 / P41970 / ELK3, ETS transcription factorENSG0000011114512
ERF / P50548 / ETS2 repressor factorENSG0000010572211
AC010616.1ENSG0000026804111
ETV3 / P41162 / ETS variant 3ENSG0000011703611
ETV3L / Q6ZN32 / ETS variant 3 likeENSG0000025383110


Protein motifs (from Interpro)
Interpro ID Name
 IPR000418  Ets domain
 IPR006715  PEA3-type ETS-domain transcription factor, N-terminal
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007274 neuromuscular synaptic transmission IEA
 biological_processGO:0007626 locomotory behavior IEA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0034599 cellular response to oxidative stress IDA
 biological_processGO:0045666 positive regulation of neuron differentiation IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IMP
 biological_processGO:0048133 male germ-line stem cell asymmetric division IEA
 biological_processGO:0050807 regulation of synapse organization IEA
 biological_processGO:0060252 positive regulation of glial cell proliferation IEA
 biological_processGO:0060762 regulation of branching involved in mammary gland duct morphogenesis IEA
 biological_processGO:0071340 skeletal muscle acetylcholine-gated channel clustering IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005886 plasma membrane IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IMP
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IMP
 molecular_functionGO:0003677 DNA binding TAS
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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