ENSMUSG00000003382


Mus musculus

Features
Gene ID: ENSMUSG00000003382
  
Biological name :Etv3
  
Synonyms : ETS translocation variant 3 / Etv3 / Q8R4Z4
  
Possible biological names infered from orthology : ETS variant 3 / P41162
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: F1
Gene start: 87525407
Gene end: 87540156
  
Corresponding Affymetrix probe sets: 10492997 (MoGene1.0st)   1418635_at (Mouse Genome 430 2.0 Array)   1418636_at (Mouse Genome 430 2.0 Array)   1418637_at (Mouse Genome 430 2.0 Array)   1456358_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000112915
Ensembl peptide - ENSMUSP00000114047
Ensembl peptide - ENSMUSP00000127419
NCBI entrez gene - 27049     See in Manteia.
MGI - MGI:1350926
RefSeq - XM_017319603
RefSeq - NM_001083318
RefSeq - NM_001286844
RefSeq - NM_012051
RefSeq - XM_006501545
RefSeq Peptide - NP_001273773
RefSeq Peptide - NP_036181
RefSeq Peptide - NP_001076787
swissprot - Q8R4Z4
swissprot - D3YVU8
Ensembl - ENSMUSG00000003382
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000027138Gallus gallus
 ENSGALG00000000669Gallus gallus
 ETV3ENSG00000117036Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Erf / ETS2 repressor factor / P50548*ENSMUSG0000004085745
Gm4881 / AC010616.1*ENSMUSG0000010836725
Elk4 / P41158 / ETS domain-containing protein Elk-4 / P28324* / ELK4, ETS transcription factor*ENSMUSG0000002643618
Elk1 / P41969 / ETS domain-containing protein Elk-1 / P19419* / ELK1, ETS transcription factor*ENSMUSG0000000940617
Elk3 / P41971 / ETS domain-containing protein Elk-3 / P41970* / ELK3, ETS transcription factor*ENSMUSG0000000839816
Fli1 / P26323 / Friend leukemia integration 1 transcription factor / Q01543* / Fli-1 proto-oncogene, ETS transcription factor*ENSMUSG0000001608715
Fev / Q8QZW2 / Protein FEV / Q99581* / FEV, ETS transcription factor*ENSMUSG0000005519714
Erg / P81270 / Transcriptional regulator ERG / P11308* / ERG, ETS transcription factor*ENSMUSG0000004073214
Ets1 / P27577 / Protein C-ets-1 / P14921* / ETS proto-oncogene 1, transcription factor*ENSMUSG0000003203512
Etv4 / P28322 / ETS translocation variant 4 / P43268* / ETS variant 4*ENSMUSG0000001772412
Etv1 / P41164 / ETS translocation variant 1 / P50549* / ETS variant 1*ENSMUSG0000000415112
Gabpa / Q00422 / GA-binding protein alpha chain / Q06546* / GA binding protein transcription factor alpha subunit*ENSMUSG0000000897612
Ets2 / P15037 / Protein C-ets-2 / P15036* / ETS proto-oncogene 2, transcription factor*ENSMUSG0000002289512
Etv5 / Q9CXC9 / ETS translocation variant 5 / P41161* / ETS variant 5*ENSMUSG0000001308912
Etv2 / P41163 / ETS translocation variant 2 / O00321* / ETS variant 2*ENSMUSG0000000631111


Protein motifs (from Interpro)
Interpro ID Name
 IPR000418  Ets domain
 IPR032929  ETS translocation variant 3
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0008285 negative regulation of cell proliferation IDA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus IDA
 cellular_componentGO:0000790 nuclear chromatin IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0017053 transcriptional repressor complex IDA
 cellular_componentGO:0090571 RNA polymerase II transcription repressor complex IDA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017151 DEAD/H-box RNA helicase binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr