ENSG00000123388


Homo sapiens

Features
Gene ID: ENSG00000123388
  
Biological name :HOXC11
  
Synonyms : homeobox C11 / HOXC11 / O43248
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: q13.13
Gene start: 53973126
Gene end: 53977643
  
Corresponding Affymetrix probe sets: 206745_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000243082
Ensembl peptide - ENSP00000446680
NCBI entrez gene - 3227     See in Manteia.
OMIM - 605559
RefSeq - NM_014212
RefSeq Peptide - NP_055027
swissprot - O43248
swissprot - J3KMZ0
Ensembl - ENSG00000123388
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hoxc11bENSDARG00000102631Danio rerio
 Q58EL0ENSDARG00000070351Danio rerio
 HOXC11ENSGALG00000042416Gallus gallus
 Hoxc11ENSMUSG00000001656Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HOXA11 / P31270 / homeobox A11ENSG0000000507353
HOXD11 / P31277 / homeobox D11ENSG0000012871346
HOXA10 / P31260 / homeobox A10ENSG0000025329322
HOXD9 / P28356 / homeobox D9ENSG0000012870922
HOXA9 / P31269 / homeobox A9ENSG0000007839922
HOXC10 / Q9NYD6 / homeobox C10ENSG0000018081822
HOXD12 / P35452 / homeobox D12ENSG0000017017821
HOXD10 / P28358 / homeobox D10ENSG0000012871021
HOXB9 / P17482 / homeobox B9ENSG0000017068920
HOXA13 / P31271 / homeobox A13ENSG0000010603120
HOXC9 / P31274 / homeobox C9ENSG0000018080620
HOXC12 / P31275 / homeobox C12ENSG0000012340719
HOXB13 / Q92826 / homeobox B13ENSG0000015918419
HOXD13 / P35453 / homeobox D13ENSG0000012871419
HOXC13 / P31276 / homeobox C13ENSG0000012336419
AC004080.3ENSG0000025718414


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa
 IPR021918  Domain of unknown function DUF3528, homeobox protein, eukaryotic


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001501 skeletal system development IEA
 biological_processGO:0001656 metanephros development IEA
 biological_processGO:0001759 organ induction IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007492 endoderm development TAS
 biological_processGO:0009952 anterior/posterior pattern specification IEA
 biological_processGO:0009954 proximal/distal pattern formation IEA
 biological_processGO:0042733 embryonic digit morphogenesis IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0060272 embryonic skeletal joint morphogenesis IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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