ENSG00000253293


Homo sapiens

Features
Gene ID: ENSG00000253293
  
Biological name :HOXA10
  
Synonyms : homeobox A10 / HOXA10 / P31260
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: p15.2
Gene start: 27170591
Gene end: 27180261
  
Corresponding Affymetrix probe sets: 213147_at (Human Genome U133 Plus 2.0 Array)   213150_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000479619
Ensembl peptide - ENSP00000283921
Ensembl peptide - ENSP00000379633
NCBI entrez gene - 3206     See in Manteia.
OMIM - 142957
RefSeq - NM_018951
RefSeq Peptide - NP_061824
swissprot - P31260
swissprot - Q5I0Y5
Ensembl - ENSG00000253293
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hoxb10aENSDARG00000011579Danio rerio
 HOXA10ENSGALG00000026631Gallus gallus
 Hoxa10ENSMUSG00000000938Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HOXD10 / P28358 / homeobox D10ENSG0000012871043
HOXC10 / Q9NYD6 / homeobox C10ENSG0000018081835
HOXD9 / P28356 / homeobox D9ENSG0000012870925
HOXB9 / P17482 / homeobox B9ENSG0000017068924
HOXA9 / P31269 / homeobox A9ENSG0000007839924
HOXC9 / P31274 / homeobox C9ENSG0000018080623
HOXD11 / P31277 / homeobox D11ENSG0000012871321
HOXA11 / P31270 / homeobox A11ENSG0000000507319
HOXC11 / O43248 / homeobox C11ENSG0000012338817
HOXD12 / P35452 / homeobox D12ENSG0000017017817
HOXC12 / P31275 / homeobox C12ENSG0000012340717
AC004080.3ENSG0000025718415
HOXA13 / P31271 / homeobox A13ENSG0000010603115
HOXD13 / P35453 / homeobox D13ENSG0000012871414
HOXC13 / P31276 / homeobox C13ENSG0000012336414
HOXB13 / Q92826 / homeobox B13ENSG0000015918413


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001501 skeletal system development IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development TAS
 biological_processGO:0007283 spermatogenesis TAS
 biological_processGO:0007338 single fertilization IEA
 biological_processGO:0008584 male gonad development IEA
 biological_processGO:0009952 anterior/posterior pattern specification IEA
 biological_processGO:0009954 proximal/distal pattern formation IEA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0030326 embryonic limb morphogenesis IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0060065 uterus development IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005667 transcription factor complex IEA
 cellular_componentGO:0005737 cytoplasm IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042826 histone deacetylase binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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