ENSG00000159184


Homo sapiens

Features
Gene ID: ENSG00000159184
  
Biological name :HOXB13
  
Synonyms : homeobox B13 / HOXB13 / Q92826
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q21.32
Gene start: 48724763
Gene end: 48729178
  
Corresponding Affymetrix probe sets: 209844_at (Human Genome U133 Plus 2.0 Array)   230105_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000290295
NCBI entrez gene - 10481     See in Manteia.
OMIM - 604607
RefSeq - NM_006361
RefSeq Peptide - NP_006352
swissprot - Q92826
Ensembl - ENSG00000159184
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HOXB13ENSGALG00000033154Gallus gallus
 Hoxb13ENSMUSG00000049604Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HOXA13 / P31271 / homeobox A13ENSG0000010603153
HOXC13 / P31276 / homeobox C13ENSG0000012336447
HOXD13 / P35453 / homeobox D13ENSG0000012871444
HOXC10 / Q9NYD6 / homeobox C10ENSG0000018081821
HOXC12 / P31275 / homeobox C12ENSG0000012340721
HOXD11 / P31277 / homeobox D11ENSG0000012871321
HOXD12 / P35452 / homeobox D12ENSG0000017017820
HOXC11 / O43248 / homeobox C11ENSG0000012338820
HOXA11 / P31270 / homeobox A11ENSG0000000507319
HOXD9 / P28356 / homeobox D9ENSG0000012870919
HOXA10 / P31260 / homeobox A10ENSG0000025329319
HOXA9 / P31269 / homeobox A9ENSG0000007839919
HOXC9 / P31274 / homeobox C9ENSG0000018080618
HOXB9 / P17482 / homeobox B9ENSG0000017068917
HOXD10 / P28358 / homeobox D10ENSG0000012871017
AC004080.3ENSG0000025718412


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR022067  Homeobox protein Hox1A3 N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0001525 angiogenesis IEP
 biological_processGO:0002009 morphogenesis of an epithelium IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0008544 epidermis development TAS
 biological_processGO:0009611 response to wounding TAS
 biological_processGO:0030850 prostate gland development IEA
 biological_processGO:0033574 response to testosterone IEA
 biological_processGO:0040008 regulation of growth IEA
 biological_processGO:0060527 prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis IEA
 biological_processGO:0060743 epithelial cell maturation involved in prostate gland development IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005667 transcription factor complex IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IC
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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