ENSG00000170178


Homo sapiens

Features
Gene ID: ENSG00000170178
  
Biological name :HOXD12
  
Synonyms : homeobox D12 / HOXD12 / P35452
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q31.1
Gene start: 176099730
Gene end: 176101193
  
Corresponding Affymetrix probe sets: 221411_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000385132
Ensembl peptide - ENSP00000385586
NCBI entrez gene - 3238     See in Manteia.
OMIM - 142988
RefSeq - NM_021193
RefSeq Peptide - NP_067016
swissprot - B5MCD3
swissprot - P35452
Ensembl - ENSG00000170178
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q90471ENSDARG00000059263Danio rerio
 HOXD12ENSGALG00000009274Gallus gallus
 Hoxd12ENSMUSG00000001823Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HOXC12 / P31275 / homeobox C12ENSG0000012340746
HOXD11 / P31277 / homeobox D11ENSG0000012871328
HOXA10 / P31260 / homeobox A10ENSG0000025329325
HOXD9 / P28356 / homeobox D9ENSG0000012870925
HOXC11 / O43248 / homeobox C11ENSG0000012338824
HOXA13 / P31271 / homeobox A13ENSG0000010603124
HOXA11 / P31270 / homeobox A11ENSG0000000507324
HOXC9 / P31274 / homeobox C9ENSG0000018080623
HOXA9 / P31269 / homeobox A9ENSG0000007839923
HOXC10 / Q9NYD6 / homeobox C10ENSG0000018081821
HOXB9 / P17482 / homeobox B9ENSG0000017068921
HOXB13 / Q92826 / homeobox B13ENSG0000015918421
HOXD13 / P35453 / homeobox D13ENSG0000012871421
HOXC13 / P31276 / homeobox C13ENSG0000012336420
HOXD10 / P28358 / homeobox D10ENSG0000012871020
AC004080.3ENSG0000025718415


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001501 skeletal system development IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007389 pattern specification process IEA
 biological_processGO:0042733 embryonic digit morphogenesis IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005667 transcription factor complex IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr