ENSG00000148948


Homo sapiens

Features
Gene ID: ENSG00000148948
  
Biological name :LRRC4C
  
Synonyms : leucine rich repeat containing 4C / LRRC4C / Q9HCJ2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: p12
Gene start: 40114203
Gene end: 41459773
  
Corresponding Affymetrix probe sets: 232226_at (Human Genome U133 Plus 2.0 Array)   241585_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000437132
Ensembl peptide - ENSP00000436976
Ensembl peptide - ENSP00000480903
Ensembl peptide - ENSP00000278198
Ensembl peptide - ENSP00000431363
Ensembl peptide - ENSP00000434761
NCBI entrez gene - 57689     See in Manteia.
OMIM - 608817
RefSeq - XM_017018079
RefSeq - NM_001258419
RefSeq - NM_020929
RefSeq - XM_017018075
RefSeq - XM_017018076
RefSeq - XM_017018077
RefSeq - XM_017018078
RefSeq - XM_011520238
RefSeq - XM_011520239
RefSeq - XM_011520240
RefSeq - XM_011520241
RefSeq - XM_011520242
RefSeq - XM_011520243
RefSeq - XM_011520244
RefSeq - XM_017018070
RefSeq - XM_017018071
RefSeq - XM_017018072
RefSeq - XM_017018073
RefSeq - XM_017018074
RefSeq Peptide - NP_001245348
RefSeq Peptide - NP_065980
swissprot - Q9HCJ2
swissprot - E9PLP4
Ensembl - ENSG00000148948
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lrrc4cENSDARG00000113411Danio rerio
 si:dkey-6l15.1ENSDARG00000016739Danio rerio
 LRRC4CENSGALG00000007948Gallus gallus
 Lrrc4cENSMUSG00000050587Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LRRC4B / Q9NT99 / leucine rich repeat containing 4BENSG0000013140964
LRRC4 / Q9HBW1 / leucine rich repeat containing 4ENSG0000012859456
LINGO3 / P0C6S8 / leucine rich repeat and Ig domain containing 3ENSG0000022000825
LINGO2 / Q7L985 / leucine rich repeat and Ig domain containing 2ENSG0000017448225
LINGO1 / Q96FE5 / leucine rich repeat and Ig domain containing 1ENSG0000016978325
LINGO4 / Q6UY18 / leucine rich repeat and Ig domain containing 4ENSG0000021317123
LRRN3 / Q9H3W5 / leucine rich repeat neuronal 3ENSG0000017311423
LRFN2 / Q9ULH4 / leucine rich repeat and fibronectin type III domain containing 2ENSG0000015656422
LRRN1 / Q6UXK5 / leucine rich repeat neuronal 1ENSG0000017592822
LRRN2 / O75325 / leucine rich repeat neuronal 2ENSG0000017038221
LRFN1 / Q9P244 / leucine rich repeat and fibronectin type III domain containing 1ENSG0000012801121
LRFN5 / Q96NI6 / leucine rich repeat and fibronectin type III domain containing 5ENSG0000016537921
LRFN3 / Q9BTN0 / leucine rich repeat and fibronectin type III domain containing 3ENSG0000012624319
LRFN4 / Q6PJG9 / leucine rich repeat and fibronectin type III domain containing 4ENSG0000017362119


Protein motifs (from Interpro)
Interpro ID Name
 IPR000372  Leucine-rich repeat N-terminal domain
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013098  Immunoglobulin I-set
 IPR013106  Immunoglobulin V-set domain
 IPR013783  Immunoglobulin-like fold
 IPR026878  Leucine-rich repeat-containing protein 4C
 IPR026906  Leucine rich repeat 5
 IPR032675  Leucine-rich repeat domain superfamily
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006469 negative regulation of protein kinase activity IBA
 biological_processGO:0019221 cytokine-mediated signaling pathway IBA
 biological_processGO:0046426 negative regulation of JAK-STAT cascade IBA
 biological_processGO:0050770 regulation of axonogenesis IDA
 cellular_componentGO:0005615 extracellular space HDA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane NAS
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0004860 protein kinase inhibitor activity IBA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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