ENSG00000126243


Homo sapiens

Features
Gene ID: ENSG00000126243
  
Biological name :LRFN3
  
Synonyms : leucine rich repeat and fibronectin type III domain containing 3 / LRFN3 / Q9BTN0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: q13.12
Gene start: 35935358
Gene end: 35945767
  
Corresponding Affymetrix probe sets: 219346_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000246529
Ensembl peptide - ENSP00000466989
NCBI entrez gene - 79414     See in Manteia.
OMIM - 612809
RefSeq - XM_017027302
RefSeq - NM_024509
RefSeq Peptide - NP_078785
swissprot - Q9BTN0
Ensembl - ENSG00000126243
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LRFN3ENSDARG00000039500Danio rerio
 Lrfn3ENSMUSG00000036957Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LRFN1 / Q9P244 / leucine rich repeat and fibronectin type III domain containing 1ENSG0000012801155
LRFN2 / Q9ULH4 / leucine rich repeat and fibronectin type III domain containing 2ENSG0000015656450
LRFN4 / Q6PJG9 / leucine rich repeat and fibronectin type III domain containing 4ENSG0000017362150
LRFN5 / Q96NI6 / leucine rich repeat and fibronectin type III domain containing 5ENSG0000016537950
LINGO3 / P0C6S8 / leucine rich repeat and Ig domain containing 3ENSG0000022000825
LRRN2 / O75325 / leucine rich repeat neuronal 2ENSG0000017038223
LINGO2 / Q7L985 / leucine rich repeat and Ig domain containing 2ENSG0000017448222
LINGO1 / Q96FE5 / leucine rich repeat and Ig domain containing 1ENSG0000016978321
LINGO4 / Q6UY18 / leucine rich repeat and Ig domain containing 4ENSG0000021317121
LRRC4B / Q9NT99 / leucine rich repeat containing 4BENSG0000013140920
LRRN3 / Q9H3W5 / leucine rich repeat neuronal 3ENSG0000017311420
LRRN1 / Q6UXK5 / leucine rich repeat neuronal 1ENSG0000017592820
LRRC4 / Q9HBW1 / leucine rich repeat containing 4ENSG0000012859419
LRRC4C / Q9HCJ2 / leucine rich repeat containing 4CENSG0000014894819


Protein motifs (from Interpro)
Interpro ID Name
 IPR000483  Cysteine-rich flanking region, C-terminal
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR003961  Fibronectin type III
 IPR007110  Immunoglobulin-like domain
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR032675  Leucine-rich repeat domain superfamily
 IPR036116  Fibronectin type III superfamily
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007409 axonogenesis IBA
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0042734 presynaptic membrane IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Synaptic adhesion-like molecules


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000132589 FLOT2 / Q14254 / flotillin 2  / reaction / complex
 ENSG00000133318 RTN3 / O95197 / reticulon 3  / reaction / complex






 

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