ENSGALG00000034970


Gallus gallus

Features
Gene ID: ENSGALG00000034970
  
Biological name :PRKCQ
  
Synonyms : PRKCQ / protein kinase C theta
  
Possible biological names infered from orthology : Q02111 / Q04759
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 3665779
Gene end: 3701334
  
Corresponding Affymetrix probe sets: Gga.13938.1.S1_at (Chicken Array)   GgaAffx.4781.1.S1_at (Chicken Array)   GgaAffx.599.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000054649
Ensembl peptide - ENSGALP00000044035
NCBI entrez gene - 776459     See in Manteia.
RefSeq - XM_015290717
RefSeq - XM_001235979
RefSeq - XM_015290648
swissprot - A0A1D5NUL7
Ensembl - ENSGALG00000034970
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 prkcqENSDARG00000034173Danio rerio
 PRKCQENSG00000065675Homo sapiens
 PrkcqENSMUSG00000026778Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PRKCD / protein kinase C delta type / P28867* / Q05655* / protein kinase C delta*ENSGALG0000000201662
PRKCH / protein kinase C eta / P23298* / P24723*ENSGALG0000001188941
PRKCE / protein kinase C epsilon / P16054* / Q02156*ENSGALG0000001000039
PRKCB / protein kinase C beta / P05771* / P68404*ENSGALG0000003794339
PRKCA / protein kinase C alpha / P17252*ENSGALG0000002595039
PRKCZ / protein kinase C zeta / Q02956* / Q05513*ENSGALG0000000127029
PRKCI / protein kinase C iota type / P41743* / Q62074* / protein kinase C iota*ENSGALG0000000936428
AKT1 / RAC-alpha serine/threonine-protein kinase / P31749* / P31750* / AKT serine/threonine kinase 1* / Mus musculus thymoma viral proto-onco 1 (Akt1), transcript variant 3, mRNA.*ENSGALG0000001162025
SGK3 / serum/glucocorticoid regulated kinase family member 3 / Q96BR1* / Q9ERE3* / serum/glucocorticoid regulated kinase 3*ENSGALG0000004357024
AKT3 / AKT serine/threonine kinase 3 / Q9WUA6* / Q9Y243* / RAC-gamma serine/threonine-protein kinase *ENSGALG0000003408124
SGK1 / Q6U1I9 / Serine/threonine-protein kinase Sgk1 / Q9WVC6* / O00141* / serum/glucocorticoid regulated kinase 1*ENSGALG0000001397123
SGK2 / SGK2, serine/threonine kinase 2 / Q9HBY8* / Q9QZS5* / Serine/threonine-protein kinase Sgk2 *ENSGALG0000000353720


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR000719  Protein kinase domain
 IPR000961  AGC-kinase, C-terminal
 IPR002219  Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR014376  Protein kinase C, delta/epsilon/eta/theta types
 IPR017441  Protein kinase, ATP binding site
 IPR017892  Protein kinase, C-terminal
 IPR020454  Diacylglycerol/phorbol-ester binding


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006509 membrane protein ectodomain proteolysis IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0032212 positive regulation of telomere maintenance via telomerase IEA
 biological_processGO:0032740 positive regulation of interleukin-17 production IEA
 biological_processGO:0032753 positive regulation of interleukin-4 production IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0042102 positive regulation of T cell proliferation IEA
 biological_processGO:0045086 positive regulation of interleukin-2 biosynthetic process IEA
 biological_processGO:0046627 negative regulation of insulin receptor signaling pathway IEA
 biological_processGO:0050870 positive regulation of T cell activation IEA
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IEA
 biological_processGO:0051973 positive regulation of telomerase activity IEA
 biological_processGO:0060326 cell chemotaxis IEA
 biological_processGO:0070233 negative regulation of T cell apoptotic process IEA
 biological_processGO:0090330 regulation of platelet aggregation IEA
 biological_processGO:1904355 positive regulation of telomere capping IEA
 biological_processGO:2000318 positive regulation of T-helper 17 type immune response IEA
 biological_processGO:2000570 positive regulation of T-helper 2 cell activation IEA
 cellular_componentGO:0001772 immunological synapse IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016235 aggresome IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004697 protein kinase C activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Apoptotic cleavage of cellular proteins
Effects of PIP2 hydrolysis
Downstream TCR signaling
FCERI mediated NF-kB activation
Netrin-1 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000004398 CARD11 / caspase recruitment domain family member 11 / Q8CIS0* / Q9BXL7* / Caspase recruitment domain-containing protein 11 *  / reaction / complex
 ENSGALG00000006418 PDPK1 / 3-phosphoinositide dependent protein kinase 1 / O15530* / Q9Z2A0*  / reaction
 ENSGALG00000007932 TRAF6 / TNF receptor associated factor 6 / P70196* / Q9Y4K3*  / complex / reaction
 ENSGALG00000016284 TAB3 / TGF-beta activated kinase 1 and MAP3K7 binding protein 3 / Q571K4* / Q8N5C8* / TGF-beta activated kinase 1/MAP3K7 binding protein 3*  / reaction / complex
 ENSGALG00000012356 TAB2 / TGF-beta activated kinase 1/MAP3K7 binding protein 2 / Q99K90* / Q9NYJ8* / TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 *  / complex / reaction
 ENSGALG00000015596 MAP3K7 / mitogen-activated protein kinase kinase kinase 7 / O43318* / Q62073*  / reaction / complex
 ENSGALG00000012150 TAB1 / TGF-beta activated kinase 1 (MAP3K7) binding protein 1 / Q15750* / Q8CF89* / TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 *  / complex / reaction
 ENSGALG00000010638 CASP3 / caspase 3 / P42574* / P70677* / Caspase-3 Caspase-3 subunit p17 Caspase-3 subunit p12*  / reaction
 ENSGALG00000028935 BCL10 / B cell CLL/lymphoma 10 / O95999* / Q9Z0H7* / B-cell lymphoma/leukemia 10 *  / complex
 ENSGALG00000030063 MALT1 / MALT1 paracaspase / Q2TBA3* / Q9UDY8* / Mucosa-associated lymphoid tissue lymphoma translocation *  / complex






 

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