ENSGALG00000009364


Gallus gallus

Features
Gene ID: ENSGALG00000009364
  
Biological name :PRKCI
  
Synonyms : PRKCI / protein kinase C iota type
  
Possible biological names infered from orthology : P41743 / protein kinase C iota / Q62074
  
Species: Gallus gallus
  
Chr. number: 9
Strand: -1
Band:
Gene start: 19891388
Gene end: 19914304
  
Corresponding Affymetrix probe sets: GgaAffx.5908.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000038526
Ensembl peptide - ENSGALP00000015235
NCBI entrez gene - 424991     See in Manteia.
RefSeq - XM_015291663
RefSeq - NM_001031319
RefSeq Peptide - NP_001026490
swissprot - E1BWA3
swissprot - F1P0L9
Ensembl - ENSGALG00000009364
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 prkciENSDARG00000021225Danio rerio
 PRKCIENSG00000163558Homo sapiens
 PrkciENSMUSG00000037643Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PRKCZ / protein kinase C zeta / Q02956* / Q05513*ENSGALG0000000127072
PRKCE / protein kinase C epsilon / P16054* / Q02156*ENSGALG0000001000037
PRKCH / protein kinase C eta / P23298* / P24723*ENSGALG0000001188937
PRKCA / protein kinase C alpha / P17252*ENSGALG0000002595036
PRKCB / protein kinase C beta / P05771* / P68404*ENSGALG0000003794335
PRKCD / protein kinase C delta type / P28867* / Q05655* / protein kinase C delta*ENSGALG0000000201633
PRKCQ / protein kinase C theta / Q02111* / Q04759*ENSGALG0000003497033
SGK3 / serum/glucocorticoid regulated kinase family member 3 / Q96BR1* / Q9ERE3* / serum/glucocorticoid regulated kinase 3*ENSGALG0000004357029
AKT3 / AKT serine/threonine kinase 3 / Q9WUA6* / Q9Y243* / RAC-gamma serine/threonine-protein kinase *ENSGALG0000003408128
AKT1 / RAC-alpha serine/threonine-protein kinase / P31749* / P31750* / AKT serine/threonine kinase 1* / Mus musculus thymoma viral proto-onco 1 (Akt1), transcript variant 3, mRNA.*ENSGALG0000001162028
SGK1 / Q6U1I9 / Serine/threonine-protein kinase Sgk1 / Q9WVC6* / O00141* / serum/glucocorticoid regulated kinase 1*ENSGALG0000001397126
SGK2 / SGK2, serine/threonine kinase 2 / Q9HBY8* / Q9QZS5* / Serine/threonine-protein kinase Sgk2 *ENSGALG0000000353724


Protein motifs (from Interpro)
Interpro ID Name
 IPR000270  PB1 domain
 IPR000719  Protein kinase domain
 IPR000961  AGC-kinase, C-terminal
 IPR002219  Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR012233  Protein kinase C
 IPR017441  Protein kinase, ATP binding site
 IPR017892  Protein kinase, C-terminal
 IPR020454  Diacylglycerol/phorbol-ester binding


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007015 actin filament organization IEA
 biological_processGO:0010976 positive regulation of neuron projection development IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IEA
 biological_processGO:0032869 cellular response to insulin stimulus IEA
 biological_processGO:0034351 negative regulation of glial cell apoptotic process IEA
 biological_processGO:0035089 establishment of apical/basal cell polarity IEA
 biological_processGO:0035556 intracellular signal transduction IBA
 biological_processGO:0042462 eye photoreceptor cell development IEA
 biological_processGO:0043524 negative regulation of neuron apoptotic process IEA
 biological_processGO:0045216 cell-cell junction organization IEA
 biological_processGO:0046326 positive regulation of glucose import IEA
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IEA
 biological_processGO:0060252 positive regulation of glial cell proliferation IEA
 biological_processGO:1903078 positive regulation of protein localization to plasma membrane IEA
 biological_processGO:2000353 positive regulation of endothelial cell apoptotic process IEA
 cellular_componentGO:0005622 intracellular IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0015630 microtubule cytoskeleton IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0043220 Schmidt-Lanterman incisure IEA
 cellular_componentGO:0045171 intercellular bridge IEA
 cellular_componentGO:0045177 apical part of cell IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IBA
 molecular_functionGO:0004697 protein kinase C activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0005543 phospholipid binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Pre-NOTCH Transcription and Translation
p75NTR recruits signalling complexes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000002556 NGF / nerve growth factor / P01138* / P01139* / Beta-nerve growth factor *  / reaction / complex
 ENSGALG00000007932 TRAF6 / TNF receptor associated factor 6 / P70196* / Q9Y4K3*  / reaction / complex
 ENSGALG00000013594 PARD6G / par-6 family cell polarity regulator gamma / Q9BYG4* / Q9JK84* / Partitioning defective 6 homolog gamma *  / complex
 ENSGALG00000007994 PARD6B / par-6 family cell polarity regulator beta / Q9BYG5* / Q9JK83* / Partitioning defective 6 homolog beta *  / complex
 ENSGALG00000001214 PARD6A / par-6 family cell polarity regulator alpha / Q9NPB6* / Q9Z101* / Partitioning defective 6 homolog alpha *  / complex
 ENSGALG00000000616 ELF3 / E74 like ETS transcription factor 3 / P78545* / Q3UPW2* / ETS-related transcription factor Elf-3 *  / reaction
 ENSGALG00000035950 NGFR / P18519 / Tumor necrosis factor receptor superfamily member 16 / P08138* / nerve growth factor receptor*  / reaction / complex






 

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