ENSGALG00000013971


Gallus gallus

Features
Gene ID: ENSGALG00000013971
  
Biological name :SGK1
  
Synonyms : Q6U1I9 / Serine/threonine-protein kinase Sgk1 / SGK1
  
Possible biological names infered from orthology : O00141 / Q9WVC6 / serum/glucocorticoid regulated kinase 1
  
Species: Gallus gallus
  
Chr. number: 3
Strand: 1
Band:
Gene start: 56365721
Gene end: 56371288
  
Corresponding Affymetrix probe sets: Gga.9334.1.S1_at (Chicken Array)   Gga.9334.2.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000031130
NCBI entrez gene - 395133     See in Manteia.
RefSeq - XM_015284007
RefSeq - NM_204476
RefSeq - XM_015284008
RefSeq Peptide - NP_989807
swissprot - Q6U1I9
Ensembl - ENSGALG00000013971
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sgk1ENSDARG00000025522Danio rerio
 SGK1ENSG00000118515Homo sapiens
 Sgk1ENSMUSG00000019970Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SGK3 / serum/glucocorticoid regulated kinase family member 3 / Q96BR1* / Q9ERE3* / serum/glucocorticoid regulated kinase 3*ENSGALG0000004357065
SGK2 / SGK2, serine/threonine kinase 2 / Q9HBY8* / Q9QZS5* / Serine/threonine-protein kinase Sgk2 *ENSGALG0000000353761
AKT1 / RAC-alpha serine/threonine-protein kinase / P31749* / P31750* / AKT serine/threonine kinase 1* / Mus musculus thymoma viral proto-onco 1 (Akt1), transcript variant 3, mRNA.*ENSGALG0000001162039
PRKCA / protein kinase C alpha / P17252*ENSGALG0000002595039
AKT3 / AKT serine/threonine kinase 3 / Q9WUA6* / Q9Y243* / RAC-gamma serine/threonine-protein kinase *ENSGALG0000003408139
PRKCD / protein kinase C delta type / P28867* / Q05655* / protein kinase C delta*ENSGALG0000000201638
PRKCB / protein kinase C beta / P05771* / P68404*ENSGALG0000003794338
PRKCE / protein kinase C epsilon / P16054* / Q02156*ENSGALG0000001000038
PRKCQ / protein kinase C theta / Q02111* / Q04759*ENSGALG0000003497038
PRKCZ / protein kinase C zeta / Q02956* / Q05513*ENSGALG0000000127037
PRKCH / protein kinase C eta / P23298* / P24723*ENSGALG0000001188937
PRKCI / protein kinase C iota type / P41743* / Q62074* / protein kinase C iota*ENSGALG0000000936436


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR000961  AGC-kinase, C-terminal
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site
 IPR017892  Protein kinase, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IBA
 biological_processGO:0035556 intracellular signal transduction IBA
 biological_processGO:0048812 neuron projection morphogenesis IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016607 nuclear speck IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IBA
 molecular_functionGO:0004712 protein serine/threonine/tyrosine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Stimuli-sensing channels
Regulation of TP53 Degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000003339 MTOR / mechanistic target of rapamycin kinase / P42345* / Q9JLN9* / Serine/threonine-protein kinase mTOR *  / reaction
 ENSGALG00000006418 PDPK1 / 3-phosphoinositide dependent protein kinase 1 / O15530* / Q9Z2A0*  / reaction
 ENSGALG00000004998 RAF1 / P05625 / RAF proto-oncogene serine/threonine-protein kinase / Q99N57* / P04049* / Raf-1 proto-oncogene, serine/threonine kinase* / Mus musculus v-raf-leukemia viral onco 1 (Raf1), t...  / complex
 ENSGALG00000009942 MDM2 / MDM2 proto-oncogene / P23804* / Q00987* / E3 ubiquitin-protein ligase Mdm2 *  / reaction
 ENSGALG00000027069 TSC22D3 / TSC22 domain family member 3 / Q99576* / Q9Z2S7* / TSC22 domain family protein 3 *  / complex
 ENSGALG00000041795 WWP1 / WW domain containing E3 ubiquitin protein ligase 1 / Q8BZZ3* / Q9H0M0*  / complex






 

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