ENSMUSG00000020081


Mus musculus

Features
Gene ID: ENSMUSG00000020081
  
Biological name :Tacr2
  
Synonyms : P30549 / tachykinin receptor 2 / Tacr2
  
Possible biological names infered from orthology : P21452
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: B4
Gene start: 62252438
Gene end: 62265990
  
Corresponding Affymetrix probe sets: 10363551 (MoGene1.0st)   1422234_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000020278
NCBI entrez gene - 21337     See in Manteia.
MGI - MGI:98477
RefSeq - NM_009314
RefSeq Peptide - NP_033340
swissprot - P30549
swissprot - Q3KP20
Ensembl - ENSMUSG00000020081
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tacr2ENSDARG00000074509Danio rerio
 TACR2ENSGALG00000004248Gallus gallus
 TACR2ENSG00000075073Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tacr3 / P47937 / tachykinin receptor 3 / P29371*ENSMUSG0000002817250
Tacr1 / P30548 / tachykinin receptor 1 / P25103*ENSMUSG0000003004349
Gpr83 / P30731 / Probable G-protein coupled receptor 83 / Q9NYM4* / G protein-coupled receptor 83*ENSMUSG0000003193228
Npy1r / Q04573 / Mus musculus neuropeptide Y receptor Y1 (Npy1r), transcript variant 2, mRNA. / P25929* / neuropeptide Y receptor Y1*ENSMUSG0000003643726
Npy2r / P97295 / Neuropeptide Y receptor type 2 / P49146* / neuropeptide Y receptor Y2*ENSMUSG0000002800423
Pgr15lENSMUSG0000003121223
Prlhr / Q6VMN6 / Prolactin-releasing peptide receptor / P49683* / prolactin releasing hormone receptor*ENSMUSG0000004505223
Npy6r / Q61212 / Neuropeptide Y receptor type 6 ENSMUSG0000003807123
Prokr1 / Q9JKL1 / Mus musculus prokineticin receptor 1 (Prokr1), transcript variant 2, mRNA. / Q8TCW9* / prokineticin receptor 1*ENSMUSG0000004940922
Prokr2 / Q8K458 / Prokineticin receptor 2 / Q8NFJ6*ENSMUSG0000005055822
Npy4r / Q61041 / Neuropeptide Y receptor type 4 / NPY4R2* / P50391* / neuropeptide Y receptor Y4* / neuropeptide Y receptor Y4-2*ENSMUSG0000004833721
Gpr165ENSMUSG0000003121021
Npy5r / O70342 / Mus musculus neuropeptide Y receptor Y5 (Npy5r), transcript variant 2, mRNA. / Q15761* / neuropeptide Y receptor Y5*ENSMUSG0000004401419


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000913  Neurokinin NK2 receptor
 IPR001681  Neurokinin receptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007217 tachykinin receptor signaling pathway IEA
 biological_processGO:0007268 chemical synaptic transmission IBA
 biological_processGO:0014057 positive regulation of acetylcholine secretion, neurotransmission IEA
 biological_processGO:0014827 intestine smooth muscle contraction IEA
 biological_processGO:0033685 negative regulation of luteinizing hormone secretion IEA
 biological_processGO:0035106 operant conditioning IEA
 biological_processGO:0043117 positive regulation of vascular permeability IEA
 biological_processGO:0043270 positive regulation of ion transport IEA
 biological_processGO:0045987 positive regulation of smooth muscle contraction IBA
 biological_processGO:0051602 response to electrical stimulus IEA
 biological_processGO:0070459 prolactin secretion IEA
 biological_processGO:0070472 regulation of uterine smooth muscle contraction IDA
 biological_processGO:0070474 positive regulation of uterine smooth muscle contraction IEA
 biological_processGO:1902093 positive regulation of flagellated sperm motility IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0036126 sperm flagellum IEA
 cellular_componentGO:0061827 sperm head IEA
 cellular_componentGO:0097225 sperm midpiece IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004995 tachykinin receptor activity IEA
 molecular_functionGO:0016497 substance K receptor activity IEA


Pathways (from Reactome)
Pathway description
Tachykinin receptors bind tachykinins
G alpha (q) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000061762 Tac1 / P41539 / tachykinin 1 / P20366* / tachykinin precursor 1*  / complex / reaction






 

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