| MP:0000031 | abnormal cochlea morphology | "any anomaly, deformity, malformation, impairment or dysfunction of the cochlea" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator, J:21484] |
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Allelic Composition: Bdnftm1(Ntf3)Pern/Bdnftm1(Ntf3)Pern
Genetic Background: involves: 129P2/OlaHsd
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| MP:0000427 | abnormal hair cycle | "aberrant growth or asynchronous timing of the hair growth " [J:65302] |
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Allelic Composition: Bdnftm1Tbn/Bdnftm1Tbn
Genetic Background: involves: 129S4/SvJae * NMRI
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| MP:0000435 | shortened head | "reduced anterior-posterior length of the head" [J:42035] |
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Allelic Composition: Bdnftm1Lfr/Bdnftm1Lfr
Genetic Background: involves: 129S2/SvPas
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| MP:0000477 | abnormal intestine morphology | "malformation of the digestive tube passing from the stomach to the anus" [J:48968] |
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Allelic Composition: Bdnftm1Par/Bdnftm1Par
Genetic Background: involves: 129S1/Sv
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| MP:0000495 | abnormal colon morphology | "malformation of the portion of the large intestine between the cecum and the rectum" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Bdnftm1Tbn/Bdnftm1Tbn
Genetic Background: involves: 129S4/SvJae * NMRI
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| MP:0000774 | reduced brain size | "smaller appearance of the brain" [J:35802] |
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Allelic Composition: Nkx3-2tm1Bobh/Nkx3-2tm1Bobh
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Bdnftm1Yab/Bdnftm1Yab,Mapttm1(cre)Nagy/Mapt+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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| MP:0000788 | abnormal cerebral cortex morphology | "malformed gray cellular mantle covering the surface of the brain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:38857] |
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Allelic Composition: Bdnftm1Krj/Bdnftm1Lfr,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129S2/SvPas * C57BL/6J
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| MP:0000805 | abnormal visual cortex morphology | "malformation or absence of the area of the occipital cortex concerned with vision" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Bdnftm1Krj/Bdnftm1Lfr,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129S2/SvPas * C57BL/6J
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| MP:0000807 | abnormal hippocampus morphology | "absent or malformed deep lying structure of the cerebrum involved with memory storage and spatial navigation" [The Atlas of Mouse Development:ISBN 0-12-402035-6, MGI:Cls, J:38857] |
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Allelic Composition: Bdnftm1Krj/Bdnftm1Lfr,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129S2/SvPas * C57BL/6J
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| MP:0000812 | abnormal dentate gyrus morphology | "absence or malformation of one of two interlocking gyri of the hippocampus that contains granule cells, which project to the pyramidal cells and interneurons of the CA3 region of the ammon gyrus" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:38857] |
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Allelic Composition: Bdnftm1Flee/Bdnftm1Flee
Genetic Background: B6.129-Bdnftm1Flee
Allelic Composition: Bdnftm1Flee/Bdnf+
Genetic Background: B6.129-Bdnftm1Flee
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| MP:0000819 | abnormal olfactory bulb morphology | "malformation or absence of the forebrain region that coordinates neuronal signaling involved in the perception of smell; it receives input from the sensory neurons and outputs to the olfactory cortex" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, Principles of Neural Science:ISBN 0-8385-8034-3, J:16461] |
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Allelic Composition: Bdnftm3Jae/Bdnftm3Jae,Tg(Camk2a-cre)93Kln/0
Genetic Background: involves: 129S4/SvJae * CBA/J
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| MP:0000836 | abnormal substantia nigra morphology | "malformation or absence of the layer of gray substance that separates the posterior parts of the cerebral peduncles (tegmentum mesencephali) from the anterior parts; it normally includes a posterior compact part with many pigmented cells (pars compacta) and an anterior reticular part whose cells contain little pigment (pars reticularis)" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Bdnftm1Krj/Bdnftm1Lfr,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S2/SvPas * C57BL/6 * CBA
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| MP:0000872 | abnormal external granule cell layer | "malformation of the transient layer of the cerebellar cortex which is composed of the dividing and migrating granule cells" [tc:Teresa Chu , Mouse Genome Informatics Curator] |
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Allelic Composition: Bdnftm1Lfr/Bdnftm1Lfr
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0000907 | small mesencephalic trigeminal nucleus | "reduced size of the group of sensory neurons residing in a long, narrow plate in the midbrain; axons pass with the trigeminal nerve" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159] |
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Allelic Composition: Bdnftm1Jae/Bdnftm1Jae
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Bdnftm1Lfr/Bdnftm1Lfr
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0000959 | abnormal somatic sensory system morphology | |
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Allelic Composition: Bdnftm1Lfr/Bdnftm1Lfr
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0000960 | abnormal sensory ganglia morphology | "malformation or absence of a group of sensory neuron cell bodies" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:64962] |
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Allelic Composition: Bdnftm1Lfr/Bdnftm1Lfr
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0000961 | abnormal dorsal root ganglia morphology | "malformed group of nerve cell bodies of each segmental nerve projecting from the spinal cord " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:60159] |
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Allelic Composition: Bdnftm1Par/Bdnftm1Par
Genetic Background: involves: 129S1/Sv
Allelic Composition: Bdnftm1Par/Bdnftm1Par,Ntf5tm1Par/Ntf5tm1Par
Genetic Background: involves: 129S1/Sv * C57BL/6
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| MP:0000964 | small dorsal root ganglia | "reduced size of the dorsal root ganglia" [J:17123] |
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Allelic Composition: Bdnftm1Lfr/Bdnftm1Lfr
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Bdnftm1Par/Bdnftm1Par
Genetic Background: involves: 129S1/Sv
Allelic Composition: Bdnftm1Tbn/Bdnftm1Tbn
Genetic Background: involves: 129S4/SvJae * NMRI
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| MP:0000965 | abnormal sensory neuron morphology | "malformation or absence of cells that innervate an effector (muscle or glandular) tissue; responsible for transmission of sensory impulses" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159] |
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Allelic Composition: Bdnftm1(Ntf3)Pern/Bdnftm1(Ntf3)Pern
Genetic Background: involves: 129P2/OlaHsd
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| MP:0000966 | reduced sensory neuron number | "fewer than normal numbers of cells that innervate an effector (muscle or glandular) tissue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159] |
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Allelic Composition: Nkx3-2tm1Bobh/Nkx3-2tm1Bobh
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Bdnftm1Jae/Bdnftm1Jae
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Bdnftm1Lfr/Bdnftm1Lfr
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Bdnftm1Par/Bdnftm1Par
Genetic Background: involves: 129S1/Sv
Allelic Composition: Bdnftm1Tbn/Bdnftm1Tbn
Genetic Background: involves: 129S4/SvJae * NMRI
Allelic Composition: Bdnftm1Jae/Bdnftm2(Ntf5)Jae,Ntrk2tm1Kln/Ntrk2tm1Kln
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Bdnftm1Par/Bdnftm1Par,Ntf3tm1Par/Ntf3tm1Par
Genetic Background: involves: 129S1/Sv
Allelic Composition: Bdnftm1Gdy/Bdnftm1Gdy,Ntf5tm1Gdy/Ntf5tm1Gdy
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Bdnftm1Jae/Bdnftm1Jae,Ntf5tm1Jae/Ntf5tm1Jae
Genetic Background: involves: 129S4/SvJae
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| MP:0000968 | abnormal sensory neuron innervation | "defective or incomplete supply of nerve fibers to sensory termini or to spinal cord" [J:31622] |
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Allelic Composition: Nkx3-2tm1Bobh/Nkx3-2tm1Bobh
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Bdnftm1Jae/Bdnftm1Jae
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Bdnftm1Par/Bdnftm1Par
Genetic Background: involves: 129S1/Sv
Allelic Composition: Bdnftm1(Ntf3)Pern/Bdnftm1(Ntf3)Pern
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Bdnftm1Jae/Bdnftm1Jae
Genetic Background: B6.129S4-Bdnftm1Jae
Allelic Composition: Bdnftm1.1Krj/Bdnftm1.1Krj
Genetic Background: involves: 129S2/SvPas
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| MP:0001007 | abnormal sympathetic system morphology | "malformation of the part of the autonomic nervous system that innervates smooth muscle, cardiac muscle and glands and mediates the body s response to stressful situations" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Bdnftm1Tbn/Bdnftm1Tbn
Genetic Background: involves: 129S2/SvPas
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| MP:0001021 | small L4 ganglion | "reduced size of L4 ganglion" [J:17792] |
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Allelic Composition: Bdnftm1Jae/Bdnftm1Jae
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Bdnftm1Par/Bdnftm1Par
Genetic Background: involves: 129S1/Sv
Allelic Composition: Bdnftm1Par/Bdnftm1Par,Ntf3tm1Par/Ntf3tm1Par
Genetic Background: involves: 129S1/Sv
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| MP:0001026 | abnormal adrenergic neuron morphology | "malformation or absence of the neurons that release catecholamines at a synapse after an impulse" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Bdnftm1Tbn/Bdnftm1Tbn
Genetic Background: involves: 129S2/SvPas
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| MP:0001065 | abnormal trigeminal nerve morphology | "malformed chief sensory nerve of the face and motor nerve of the muscles of mastication; has three major divisions: ophthalmic, maxillary and mandibular " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, Principles of Neural Science:ISBN 0-8385-8034-3, J:33038] |
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Allelic Composition: Bdnftm1Jae/Bdnftm1Jae
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Bdnftm1Jae/Bdnftm1Jae,Ntf5tm1Jae/Ntf5tm1Jae
Genetic Background: involves: 129S4/SvJae
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| MP:0001081 | abnormal cranial ganglia morphology | "any anomaly, deformity, or malformation of the groups of nerve cell bodies associated with the twelve cranial nerves" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:45302] |
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Allelic Composition: Bdnftm1Lfr/Bdnftm1Lfr
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0001082 | abnormal geniculate ganglion morphology | "malformed group of sensory neuron cell bodies associated with the facial nerve (seventh cranial nerve)" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:45302] |
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Allelic Composition: Bdnftm1(Ntf3)Pern/Bdnftm1(Ntf3)Pern
Genetic Background: involves: 129P2/OlaHsd
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| MP:0001083 | small geniculate ganglion | "reduced size of the geniculate ganglion or decreased size of sensory neuron cell bodies associated with the facial nerve" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Bdnftm1Jae/Bdnftm1Jae
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Bdnftm1Lfr/Bdnftm1Lfr
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Bdnftm1Par/Bdnftm1Par
Genetic Background: involves: 129S1/Sv
Allelic Composition: Bdnftm1Par/Bdnftm1Par,Ntf3tm1Par/Ntf3tm1Par
Genetic Background: involves: 129S1/Sv
Allelic Composition: Bdnftm1Jae/Bdnftm1Jae,Ntf5tm1Jae/Ntf5tm1Jae
Genetic Background: involves: 129S4/SvJae
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| MP:0001085 | small petrosal ganglion | "reduced size of the petrosal ganglion" [J:25565] |
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Allelic Composition: Nkx3-2tm1Bobh/Nkx3-2tm1Bobh
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Bdnftm1Jae/Bdnftm1Jae
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Bdnftm1Lfr/Bdnftm1Lfr
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Bdnftm1Par/Bdnftm1Par
Genetic Background: involves: 129S1/Sv
Allelic Composition: Bdnftm1Par/Bdnftm1Par,Ntf3tm1Par/Ntf3tm1Par
Genetic Background: involves: 129S1/Sv
Allelic Composition: Bdnftm1Gdy/Bdnftm1Gdy,Ntf5tm1Gdy/Ntf5tm1Gdy
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Bdnftm1Jae/Bdnftm1Jae,Ntf5tm1Jae/Ntf5tm1Jae
Genetic Background: involves: 129S4/SvJae
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| MP:0001088 | small nodose ganglion | "reduced size of the nodose ganglion" [J:25565, J:17123] |
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Allelic Composition: Nkx3-2tm1Bobh/Nkx3-2tm1Bobh
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Bdnftm1Jae/Bdnftm1Jae
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Bdnftm1Lfr/Bdnftm1Lfr
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Bdnftm1Par/Bdnftm1Par
Genetic Background: involves: 129S1/Sv
Allelic Composition: Bdnftm1(Ntf3)Pern/Bdnftm1(Ntf3)Pern
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Bdnftm1Par/Bdnftm1Par,Ntf3tm1Par/Ntf3tm1Par
Genetic Background: involves: 129S1/Sv
Allelic Composition: Bdnftm1Gdy/Bdnftm1Gdy,Ntf5tm1Gdy/Ntf5tm1Gdy
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Bdnftm1Jae/Bdnftm1Jae,Ntf5tm1Jae/Ntf5tm1Jae
Genetic Background: involves: 129S4/SvJae
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| MP:0001093 | small trigeminal ganglion | "reduced size of the trigeminal ganglion" [J:25565, J:17123] |
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Allelic Composition: Nkx3-2tm1Bobh/Nkx3-2tm1Bobh
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Bdnftm1Jae/Bdnftm1Jae
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Bdnftm1Par/Bdnftm1Par
Genetic Background: involves: 129S1/Sv
Allelic Composition: Bdnftm1Par/Bdnftm1Par,Ntf3tm1Par/Ntf3tm1Par
Genetic Background: involves: 129S1/Sv
Allelic Composition: Bdnftm1Gdy/Bdnftm1Gdy,Ntf5tm1Gdy/Ntf5tm1Gdy
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Bdnftm1Jae/Bdnftm1Jae,Ntf5tm1Jae/Ntf5tm1Jae
Genetic Background: involves: 129S4/SvJae
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| MP:0001257 | increased body length | "increased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator] |
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Allelic Composition: Bdnftm3Jae/Bdnftm3Jae,Tg(Camk2a-cre)159Kln/0
Genetic Background: involves: 129S4/SvJae * CBA/J
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| MP:0001260 | increased body weight | "greater than normal average weight " [J:33400] |
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Allelic Composition: Agtr2tm1Tin/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Bdnftm1Flee/Bdnftm1Flee
Genetic Background: B6.129-Bdnftm1Flee
Allelic Composition: Bdnftm1Par/Bdnf+
Genetic Background: involves: 129S1/Sv
Allelic Composition: Bdnftm1Par/Bdnf+
Genetic Background: B6.129S1-Bdnftm1Par
Allelic Composition: Bdnftm1Par/Bdnf+,Ntrk2tm1.1Tes/Ntrk2tm1.1Tes
Genetic Background: B6.129S1-Bdnftm1Par Ntrk2tm1.1Tes
Allelic Composition: Bdnftm1Yab/Bdnftm1Yab,Mapttm1(cre)Nagy/Mapt+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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| MP:0001261 | obese | "excessively fat; an increase in fat in the subcutaneous connective tissue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator] |
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Allelic Composition: Bcl2tm1Dlo/Bcl2tm1Dlo,Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Genetic Background: B6.129-Bcl2tm1Dlo Bcl2l11tm1.1Ast
Allelic Composition: Bdnftm3Jae/Bdnftm3Jae,Tg(Camk2a-cre)93Kln/0
Genetic Background: involves: 129S4/SvJae * CBA/J
Allelic Composition: Bdnftm1Krj/Bdnftm1Lfr,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129S2/SvPas * C57BL/6J
Allelic Composition: Bdnftm1Lfr/Bdnf+
Genetic Background: involves: 129S2/SvPas * C57BL/6J
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| MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
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Allelic Composition: Bdnftm1Par/Bdnftm1Par
Genetic Background: involves: 129S1/Sv
Allelic Composition: Bdnftm2(Ntf5)Jae/Bdnftm2(Ntf5)Jae
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Bdnftm1Krj/Bdnftm1Lfr,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129S2/SvPas * C57BL/6J
Allelic Composition: Bdnftm1Yab/Bdnftm1Yab,Mapttm1(cre)Nagy/Mapt+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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| MP:0001263 | weight loss | "progressive reduction of body weight below normal average for age" [J:45400] |
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Allelic Composition: Spp1Ric-s/Spp1+
Genetic Background: SJL/J
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| MP:0001265 | reduced body size | "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170] |
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Allelic Composition: Nkx3-2tm1Bobh/Nkx3-2tm1Bobh
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Bdnftm1Lfr/Bdnftm1Lfr
Genetic Background: involves: 129S2/SvPas
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| MP:0001290 | delayed eyelid opening | "late average time for the first postnatal eye opening" [J:17792] |
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Allelic Composition: Bdnftm1Krj/Bdnftm1Lfr,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129S2/SvPas * C57BL/6J
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| MP:0001330 | abnormal optic nerve morphology | "malformation, misprojection or atrophy in the second cranial nerve which is responsible for conveying visual information from the retina to the brain" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Bdnftm1Yab/Bdnftm1Yab,Mapttm1(cre)Nagy/Mapt+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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| MP:0001354 | increased aggression towards males | "when compared to controls, subjects exhibit greater than the normal level of domineering, assaultive posture and/or hostile physical action toward male mice" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, Webster s II New College Dictionary:ISBN 0-395-70869-9] |
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Allelic Composition: Bdnftm3Jae/Bdnftm3Jae,Tg(Camk2a-cre)93Kln/0
Genetic Background: involves: 129S4/SvJae * CBA/J
Allelic Composition: Bdnftm1Flee/Bdnftm1Flee
Genetic Background: B6.129-Bdnftm1Flee
Allelic Composition: Bdnftm1Par/Bdnf+
Genetic Background: involves: 129S1/Sv
Allelic Composition: Bdnftm1Par/Bdnf+
Genetic Background: B6.129S1-Bdnftm1Par
Allelic Composition: Bdnftm1Par/Bdnf+,Ntrk2tm1.1Tes/Ntrk2tm1.1Tes
Genetic Background: B6.129S1-Bdnftm1Par Ntrk2tm1.1Tes
Allelic Composition: Bdnftm1Par/Bdnf+,Ntrk2tm1.1Tes/Ntrk2+
Genetic Background: B6.129S1-Bdnftm1Par Ntrk2tm1.1Tes
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| MP:0001363 | increased anxiety-related response | "when compared to controls, subjects exhibit more responses thought to be indicative of anxiety in behavioral tests" [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:49752, J:53060] |
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Allelic Composition: Bdnftm3Jae/Bdnftm3Jae,Tg(Camk2a-cre)159Kln/0
Genetic Background: involves: 129S4/SvJae * CBA/J
Allelic Composition: Bdnftm1Flee/Bdnftm1Flee
Genetic Background: B6.129-Bdnftm1Flee
Allelic Composition: Bdnftm1Par/Bdnf+
Genetic Background: involves: 129S1/Sv
Allelic Composition: Bdnftm1Yab/Bdnftm1Yab,Mapttm1(cre)Nagy/Mapt+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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| MP:0001393 | ataxia | "inability to coordinate voluntary muscular movements" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:67231] |
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Allelic Composition: Bdnftm1Jae/Bdnftm1Jae
Genetic Background: involves: 129S4/SvJae
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| MP:0001394 | circling | "repeated, compulsive movement in a circle; often associated with inner ear defects" [MGI:CLS, J:61295] |
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Allelic Composition: Bdnftm1Jae/Bdnftm1Jae
Genetic Background: involves: 129S4/SvJae
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| MP:0001399 | hyperactivity | "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125] |
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Allelic Composition: Nkx3-2tm1Bobh/Nkx3-2tm1Bobh
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Bdnftm1Jae/Bdnftm1Jae
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Bdnftm3Jae/Bdnftm3Jae,Tg(Camk2a-cre)159Kln/0
Genetic Background: involves: 129S4/SvJae * CBA/J
Allelic Composition: Bdnftm3Jae/Bdnftm3Jae,Tg(Camk2a-cre)93Kln/0
Genetic Background: involves: 129S4/SvJae * CBA/J
Allelic Composition: Bdnftm3Jae/Bdnftm3Jae,Tg(Eno2tTA)5030Nes/0,Tg(tetO-cre)1Jaw/0
Genetic Background: involves: 129/Sv * C57BL/6 * ICR * SJL
Allelic Composition: Bdnftm2(Ntf5)Jae/Bdnftm2(Ntf5)Jae,Ntrk2tm1Kln/Ntrk2tm1Kln
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Bdnftm1Jae/Bdnftm2(Ntf5)Jae,Ntrk2tm1Kln/Ntrk2tm1Kln
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Bdnftm1Gdy/Bdnftm1Gdy,Ntf5tm1Gdy/Ntf5tm1Gdy
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Bdnftm1Limm/Bdnftm1Limm,Tg(Camk2a-cre)T50Stl/0
Genetic Background: involves: BALB/c * C57BL/6
Allelic Composition: Bdnftm1Limm/Bdnftm1Limm,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: FVB/N
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| MP:0001402 | hypoactivity | "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289] |
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Allelic Composition: Spp1Ric-s/Spp1+
Genetic Background: SJL/J
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| MP:0001405 | impaired coordination | "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Agtr2tm1Tin/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Bdnftm1Krj/Bdnftm1Lfr,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S2/SvPas * C57BL/6 * CBA
Allelic Composition: Bdnftm1Jae/Bdnftm1Jae,Ntf5tm1Jae/Ntf5tm1Jae
Genetic Background: involves: 129S4/SvJae
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| MP:0001410 | head bobbing | "compulsive up and down movement of the head" [J:17123] |
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Allelic Composition: Bdnftm1Jae/Bdnftm1Jae
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Bdnftm1Jae/Bdnftm2(Ntf5)Jae,Ntrk2tm1Kln/Ntrk2tm1Kln
Genetic Background: involves: 129S4/SvJae
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| MP:0001411 | spinning | "compulsive rolling of the body" [J:17123] |
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Allelic Composition: Bdnftm1Jae/Bdnftm1Jae
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Bdnftm1Lfr/Bdnftm1Lfr
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Bdnftm1Jae/Bdnftm2(Ntf5)Jae,Ntrk2tm1Kln/Ntrk2tm1Kln
Genetic Background: involves: 129S4/SvJae
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| MP:0001412 | excessive scratching | "compulsive scraping of the skin, usually with the nails" [J:61340] |
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Allelic Composition: Bdnftm1Tbn/Bdnf+
Genetic Background: involves: 129S4/SvJae * NMRI
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| MP:0001417 | decreased exploration in new environment | "less amount of time spent investigating a new location" [J:79870] |
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Allelic Composition: Bdnftm1Flee/Bdnftm1Flee
Genetic Background: B6.129-Bdnftm1Flee
Allelic Composition: Bdnftm1Par/Bdnf+
Genetic Background: involves: 129S1/Sv
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| MP:0001423 | abnormal liquid preference | "the desire to drink more or less fluids than average, or to drink unusual fluids" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Csrnp3tm1Jni/Csrnp3tm1Jni,Csrnp1tm1Jni/Csrnp1tm1Jni,Csrnp2tm1Jni/Csrnp2tm1Jni
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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| MP:0001433 | polyphagia | "eating to excess" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Bdnftm3Jae/Bdnftm3Jae,Tg(Camk2a-cre)159Kln/0
Genetic Background: involves: 129S4/SvJae * CBA/J
Allelic Composition: Bdnftm1Par/Bdnf+
Genetic Background: B6.129S1-Bdnftm1Par
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| MP:0001447 | abnormal nest building behavior | "deviation from the usual behavior of mice to build sleeping nests out of any available materials; also of female mice to bulid nests to protect offspring" [J:42758, What s wrong with my mouse?:ISBN 0-471-31639-3] |
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Allelic Composition: Pth1rtm1Hmk/Pth1rtm1Hmk
Genetic Background: involves: 129X1/SvJ * Black Swiss * C57BL/6
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| MP:0001454 | abnormal cued conditioning behavior | "defect in the ability of an animal to learn and remember an association between an an aversive experience (the unconditioned stimulus (US), ususally a shock) and a neutral stimulus (the conditioned stimulus (CS), usually an auditory cue or light)" [CFG:Center for Functional Genomics , Northwestern University] |
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Allelic Composition: Utp14bjsd/Utp14bjsd
Genetic Background: involves: C3H/HeJ * C57BL/6J
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| MP:0001469 | abnormal contextual conditioning | "defect in the ability of an animal to learn and remember an association between an an aversive experience (the unconditioned stimulus (US), ususally a shock) and a neutral stimulus (the conditioned stimulus (CS), or the environmental context in this case)" [CFG:Center for Functional Genomics , Northwestern University] |
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Allelic Composition: Utp14bjsd/Utp14bjsd
Genetic Background: involves: C3H/HeJ * C57BL/6J
Allelic Composition: Bdnftm1Flee/Bdnftm1Flee
Genetic Background: B6.129-Bdnftm1Flee
Allelic Composition: Bdnftm1Flee/Bdnf+
Genetic Background: B6.129-Bdnftm1Flee
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| MP:0001473 | reduced long term potentiation | "less than the normal persistent robust synaptic response induced by synchronous stimulation of pre- and postsynaptic cells " [Principles of Neural Science:ISBN 0-8385-8034-3] |
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Allelic Composition: Bdnftm1Tbn/Bdnftm1Tbn
Genetic Background: involves: 129S4/SvJae * NMRI
Allelic Composition: Bdnftm1Tbn/Bdnf+
Genetic Background: involves: 129S4/SvJae * NMRI
Allelic Composition: Bdnftm1Sieg/Bdnftm1Sieg,Tg(Camk2a-cre)1Szi/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * CBA
Allelic Composition: Bdnftm3Jae/Bdnftm3Jae,Tg(Eno2tTA)5030Nes/0,Tg(tetO-cre)1Jaw/0
Genetic Background: involves: 129/Sv * C57BL/6 * ICR * SJL
Allelic Composition: Bdnftm1Msd/Bdnftm1Msd,Mapttm1(cre)Nagy/Mapt+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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| MP:0001499 | kindling | "long-lasting epileptogenic changes induced by daily sub threshold electrical brain stimulation, induced model for epilepsy " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:45446] |
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Allelic Composition: Cd19tm1(cre)Cgn/Cd19+,Tgfbr2tm1Roes/Tgfbr2tm1Roes
Genetic Background: involves: 129P2/OlaHsd * BALB/c
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| MP:0001505 | hunched posture | "stooped low with the limbs pulled in close to the body and arched back" [J:67231, J:30404] |
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Allelic Composition: Bdnftm1Jae/Bdnftm1Jae
Genetic Background: involves: 129S4/SvJae
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| MP:0001513 | limb grasping | "mice clasp front and/or hind feet almost immediately upon being lifted by tail" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator] |
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Allelic Composition: Bdnftm3Jae/Bdnftm3Jae,Tg(Camk2a-cre)159Kln/0
Genetic Background: involves: 129S4/SvJae * CBA/J
Allelic Composition: Bdnftm1Krj/Bdnftm1Lfr,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129S2/SvPas * C57BL/6J
Allelic Composition: Bdnftm1Krj/Bdnftm1Lfr,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S2/SvPas * C57BL/6 * CBA
Allelic Composition: Bdnftm1Yab/Bdnftm1Yab,Mapttm1(cre)Nagy/Mapt+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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| MP:0001516 | abnormal motor coordination/ balance | "altered ability of an animal to maintain skillful and effective interaction of movements or maintenance of equilibrium" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Nkx3-2tm1Bobh/Nkx3-2tm1Bobh
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Bdnftm1Gdy/Bdnftm1Gdy,Ntf5tm1Gdy/Ntf5tm1Gdy
Genetic Background: involves: 129P2/OlaHsd
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| MP:0001523 | impaired righting response | "reduced ability or greater amount of time needed to recover from supine position" [J:25565] |
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Allelic Composition: Nkx3-2tm1Bobh/Nkx3-2tm1Bobh
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Bdnftm1Lfr/Bdnftm1Lfr
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Bdnftm1Gdy/Bdnftm1Gdy,Ntf5tm1Gdy/Ntf5tm1Gdy
Genetic Background: involves: 129P2/OlaHsd
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| MP:0001524 | impaired limb coordination | "reduced ability to organize limb movements to execute complex maneuvers, such as walking" [J:64962, MGI:CLS, J:17123] |
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Allelic Composition: Bdnftm1Jae/Bdnftm1Jae
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Bdnftm1Tbn/Bdnftm1Tbn
Genetic Background: involves: 129S4/SvJae * NMRI
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| MP:0001525 | impaired balance | "reduced ability of an animal to maintain equilibrium" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:64962, J:17123] |
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Allelic Composition: Bdnftm1Jae/Bdnftm1Jae
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Bdnftm1Tbn/Bdnftm1Tbn
Genetic Background: involves: 129S4/SvJae * NMRI
Allelic Composition: Bdnftm1(Ntf3)Pern/Bdnftm1(Ntf3)Pern
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Bdnftm1Jae/Bdnftm1Jae,Ntf5tm1Jae/Ntf5tm1Jae
Genetic Background: involves: 129S4/SvJae
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| MP:0001732 | postnatal growth retardation | "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Nkx3-2tm1Bobh/Nkx3-2tm1Bobh
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Bdnftm1Tbn/Bdnftm1Tbn
Genetic Background: involves: 129S4/SvJae * NMRI
Allelic Composition: Bdnftm1Gdy/Bdnftm1Gdy,Ntf5tm1Gdy/Ntf5tm1Gdy
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Bdnftm1Jae/Bdnftm1Jae,Ntf5tm1Jae/Ntf5tm1Jae
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Bdnftm1Yab/Bdnftm1Yab,Mapttm1(cre)Nagy/Mapt+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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| MP:0001764 | abnormal homeostasis | "anomaly in the state of equilibrium in the body with respect to various functions and to chemical composition of the fluids and tissues" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Bdnftm3Jae/Bdnftm3Jae,Tg(Camk2a-cre)159Kln/0
Genetic Background: involves: 129S4/SvJae * CBA/J
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| MP:0001900 | impaired synaptic plasticity | "decreased or inability of the nervous system to change its reactivity as a result of successive activations " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Bdnftm1Tbn/Bdnftm1Tbn
Genetic Background: involves: 129S4/SvJae * NMRI
Allelic Composition: Bdnftm1Tbn/Bdnf+
Genetic Background: involves: 129S4/SvJae * NMRI
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| MP:0001921 | reduced fertility | "diminished ability to produce live offspring" [J:65030] |
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Allelic Composition: Bdnftm1Krj/Bdnftm1Lfr,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129S2/SvPas * C57BL/6J
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| MP:0001922 | reduced male fertility | "reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340] |
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Allelic Composition: Bdnftm2(Ntf5)Jae/Bdnftm2(Ntf5)Jae
Genetic Background: involves: 129S4/SvJae
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| MP:0001923 | reduced female fertility | "reduced ability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409] |
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Allelic Composition: Bdnftm3Jae/Bdnftm3Jae,Tg(Camk2a-cre)93Kln/0
Genetic Background: involves: 129S4/SvJae * CBA/J
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| MP:0001926 | female infertility | "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193] |
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Allelic Composition: Bdnftm2(Ntf5)Jae/Bdnftm2(Ntf5)Jae
Genetic Background: involves: 129S4/SvJae
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| MP:0001967 | deafness | "inability to hear" [J:57651] |
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Allelic Composition: Bdnftm1Jae/Bdnftm1Jae
Genetic Background: involves: 129S4/SvJae
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| MP:0002066 | abnormal motor capabilities/coordination/movement | "altered ability to coordinate voluntary movement or repetitive, compulsive movements" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Bdnftm1Jae/Bdnftm1Jae
Genetic Background: involves: 129S4/SvJae
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| MP:0002079 | increased circulating insulin level | "greater than normal levels of insulin in blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Bdnftm3Jae/Bdnftm3Jae,Tg(Camk2a-cre)93Kln/0
Genetic Background: involves: 129S4/SvJae * CBA/J
Allelic Composition: Bdnftm1Par/Bdnf+
Genetic Background: B6.129S1-Bdnftm1Par
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| MP:0002083 | premature death | "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Agtr2tm1Tin/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Bdnftm1Krj/Bdnftm1Lfr,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129S2/SvPas * C57BL/6J
Allelic Composition: Bdnftm3Jae/Bdnftm3Jae,Mecp2tm1.1Jae/Y,Tg(Camk2a-cre)93Kln/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * CBA/J
Allelic Composition: Bdnftm3Jae/Bdnf+,Mecp2tm1.1Jae/Y,Tg(Camk2a-cre)93Kln/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * CBA/J
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| MP:0002169 | no phenotype detected | "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Bdnftm3Jae/Bdnftm3Jae,Tg(Camk2a-cre)93Kln/0
Genetic Background: involves: 129S4/SvJae * CBA/J
Allelic Composition: Bdnftm1Sieg/Bdnftm1Sieg
Genetic Background: involves: 129S/SvEv * C57
Allelic Composition: Bdnftm1Sieg/Bdnftm1Sieg,Tg(Camk2a-cre)3Szi/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * CBA
Allelic Composition: Bdnftm1Jae/Bdnftm2(Ntf5)Jae
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Bdnftm1.1Tes/Bdnftm1.1Tes
Genetic Background: B6.129X1-Bdnftm1.1Tes
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| MP:0002175 | low brain weight | "lower than average weight of the brain" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Bdnftm3Jae/Bdnftm3Jae,Tg(Camk2a-cre)93Kln/0
Genetic Background: involves: 129S4/SvJae * CBA/J
Allelic Composition: Bdnftm1Yab/Bdnftm1Yab,Mapttm1(cre)Nagy/Mapt+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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| MP:0002184 | abnormal innervation | "the malformation, misprojection or malfunction of the connection of nerve fibers with a target" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Bdnftm1Jae/Bdnftm1Jae
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Bdnftm1(Ntf3)Pern/Bdnftm1(Ntf3)Pern
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Bdnftm1Tbn/Bdnftm1Tbn
Genetic Background: involves: 129S2/SvPas
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| MP:0002206 | abnormal CNS synaptic transmission | "defect in the communication from a neuron to a target across a synapse in the central nervous system" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Bdnftm1Par/Bdnf+
Genetic Background: B6.129S1-Bdnftm1Par
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| MP:0002272 | abnormal nervous system electrophysiology | "anomaly in the function of the nervous system as it relates to electrical phenomena" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Smarca1tm1.1Pick/Y
Genetic Background: involves: 129S4/SvJae * CD-1
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| MP:0002655 | abnormal keratinocyte morphology | "structural or developmental anomaly of the cells of the epidermis that produce keratin in the process of differentiating into the dead and fully keratinized cells of the stratum corneum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Bdnftm1Tbn/Bdnftm1Tbn
Genetic Background: involves: 129S2/SvPas
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| MP:0002752 | abnormal somatic nervous system morphology | "malformation or absence of any of the cranial and spinal nerves or their ganglia or the peripheral sensory receptors" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Bdnftm1Par/Bdnftm1Par
Genetic Background: involves: 129S1/Sv
Allelic Composition: Bdnftm1Par/Bdnftm1Par,Ntf3tm1Par/Ntf3tm1Par
Genetic Background: involves: 129S1/Sv
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| MP:0002757 | reduced vertical activity | "lesser than average time spent jumping or rearing" [J:82829, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Bdnftm1Par/Bdnf+
Genetic Background: B6.129S1-Bdnftm1Par
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| MP:0002855 | abnormal cochlear ganglion morphology | "malformation, malfunction or absence of the group of nerve cell bodies that conveys auditory sensation from the organ of Corti to the hindbrain and resides on the cochlear part of the vestibulocochlear nerve (eighth cranial nerve)" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Bdnftm1Jae/Bdnftm1Jae
Genetic Background: involves: 129S4/SvJae
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| MP:0002856 | abnormal vestibular ganglion morphology | "malformation of the group of neurons associated with the vestibular part of the eighth cranial nerve that are involved in equilibration" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Bdnftm1Jae/Bdnftm1Jae
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Bdnftm1Lfr/Bdnftm1Lfr
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Bdnftm1(Ntf3)Pern/Bdnftm1(Ntf3)Pern
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Bdnftm1Par/Bdnftm1Par,Ntf3tm1Par/Ntf3tm1Par
Genetic Background: involves: 129S1/Sv
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| MP:0002882 | abnormal neuron | "anomaly in the functional cells of the nervous system that receive, conduct, and transmit impulses " [MeSH:National Library of Medicine - Medical Subject Headings, 2003] |
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Allelic Composition: Spp1Ric-s/Spp1+
Genetic Background: SJL/J
Allelic Composition: Bdnftm1Jae/Bdnftm1Jae
Genetic Background: involves: 129S4/SvJae * BALB/c
Allelic Composition: Bdnftm1Yab/Bdnftm1Yab,Mapttm1(cre)Nagy/Mapt+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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| MP:0002912 | abnormal excitatory postsynaptic potential | "defect in the potential detected in postsynaptic cells when an excitatory impulse arrives at the synapse causing depolarization" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3] |
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Allelic Composition: Bdnftm1Tbn/Bdnftm1Tbn
Genetic Background: involves: 129S4/SvJae * NMRI
Allelic Composition: Bdnftm1Tbn/Bdnf+
Genetic Background: involves: 129S4/SvJae * NMRI
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| MP:0002945 | abnormal inhibitory postsynaptic currents | "defect in the size or duration of currents detected in postsynaptic cells when an inhibitory impulse arrives at the synapse causing hyperpolarization" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3] |
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Allelic Composition: Btlatm1Dgra/Btlatm1Dgra,Tg(TcraTcrb)1100Mjb/?
Genetic Background: involves: C57BL/6
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| MP:0003202 | abnormal neuron apoptosis | "change in the timing or the number of neurons undergoing programmed cell death" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Bdnftm1Jae/Bdnftm1Jae
Genetic Background: involves: 129S4/SvJae * BALB/c
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| MP:0003203 | increased neuron apoptosis | "increase in the number of neurons undergoing programmed cell death" [RGD:Rat Genome Database submission] |
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Allelic Composition: Bdnftm1Jae/Bdnftm1Jae
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Bdnftm1Par/Bdnftm1Par
Genetic Background: involves: 129S1/Sv
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| MP:0003212 | susceptibility to age related obesity | "increased probability of excessive weight gain that is progressive with age" [RGD:Rat Genome Database submission] |
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Allelic Composition: Bdnftm1Par/Bdnf+
Genetic Background: B6.129S1-Bdnftm1Par
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| MP:0003245 | abnormal GABA neuron morphology | "malformation or absence of the neurons that utilize gamma-aminobutyric acid as a neurotransmitter " [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3] |
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Allelic Composition: Smarca1tm1.1Pick/Y
Genetic Background: involves: 129S4/SvJae * CD-1
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| MP:0003313 | abnormal locomotor activation | "altered ability or desire of an animal to initiate locomotor activity" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Bdnftm1Lfr/Bdnftm1Lfr
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Bdnftm1Par/Bdnf+
Genetic Background: B6.129S1-Bdnftm1Par
Allelic Composition: Bdnftm1Yab/Bdnftm1Yab,Mapttm1(cre)Nagy/Mapt+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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| MP:0003360 | depression-related behavior | |
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Allelic Composition: Bdnftm1Limm/Bdnftm1Limm,Tg(Camk2a-cre)T50Stl/0
Genetic Background: involves: BALB/c * C57BL/6
Allelic Composition: Bdnftm1Limm/Bdnftm1Limm,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: FVB/N
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| MP:0003633 | abnormal nervous system physiology | |
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Allelic Composition: Btlatm1Dgra/Btlatm1Dgra,Tg(TcraTcrb)1100Mjb/?
Genetic Background: involves: C57BL/6
Allelic Composition: Bdnftm1Krj/Bdnftm1Krj
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0003703 | abnormal vestibulocochlear ganglion morphology | "malformed group of neuron cell bodies associated with the eighth cranial nerve during embryogenesis; splits in later development to form the cochlear and vestibular ganglia" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Bdnftm1Par/Bdnftm1Par,Ntf3tm1Par/Ntf3tm1Par
Genetic Background: involves: 129S1/Sv
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| MP:0003877 | abnormal serotonergic neuron morphology | "malformation or absence of the neurons that secrete serotonin" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:54240] |
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Allelic Composition: Bdnftm1Par/Bdnf+
Genetic Background: B6.129S1-Bdnftm1Par
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| MP:0003982 | increased cholesterol level | "greater than normal concentration in the body of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Bdnftm3Jae/Bdnftm3Jae,Tg(Camk2a-cre)93Kln/0
Genetic Background: involves: 129S4/SvJae * CBA/J
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| MP:0003987 | small vestibular ganglion | "reduced size of the vestibular ganglion or of the sensory neuron cell bodies associated with the eighth cranial nerve" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Nkx3-2tm1Bobh/Nkx3-2tm1Bobh
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Bdnftm1Jae/Bdnftm1Jae
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Bdnftm1Gdy/Bdnftm1Gdy,Ntf5tm1Gdy/Ntf5tm1Gdy
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Bdnftm1Gdy/Bdnf+
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Bdnftm1Jae/Bdnftm1Jae,Ntf5tm1Jae/Ntf5tm1Jae
Genetic Background: involves: 129S4/SvJae
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| MP:0003989 | abnormal barrel cortex morphology | "malformation of the discrete functional units of the somatosensory cortex that processes tactile information derived from the vibrissae" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Bdnftm1Par/Bdnftm1Par
Genetic Background: involves: 129S1/Sv
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| MP:0004077 | abnormal striatum morphology | "malformation of a large cluster of dopaminergic nerve cells, consisting of the caudate nucleus and the putamen, that controls movement, balance, and walking" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3] |
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Allelic Composition: Spp1Ric-s/Spp1+
Genetic Background: SJL/J
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| MP:0004101 | abnormal brain interneuron morphology | "malformation or absence of neurons that exclusively interact with other neurons in the brain; this includes most brain neuronal cell types" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Btlatm1Dgra/Btlatm1Dgra,Tg(TcraTcrb)1100Mjb/?
Genetic Background: involves: C57BL/6
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| MP:0004249 | abnormal crista ampullaris morphology | "anomaly in the elevation found on the inner surface of the ampullae of each semicircular duct; filaments of the vestibular nerve pass through the crista to reach hair cells on its surface; the hair cells are capped by the cupula, a gelatinous protein-polysaccharide mass" [J:60193, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bdnftm1Jae/Bdnftm1Jae
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Bdnftm1(Ntf3)Pern/Bdnftm1(Ntf3)Pern
Genetic Background: involves: 129P2/OlaHsd
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| MP:0004298 | vestibular ganglion degeneration | "loss of the group of bipolar sensory nerve cell bodies concerned with equilibration that form a swelling on the vestibular part of the eighth cranial nerve in the fundus of the internal acoustic meatus" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Nkx3-2tm1Bobh/Nkx3-2tm1Bobh
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Bdnftm1(Ntf3)Pern/Bdnftm1(Ntf3)Pern
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Bdnftm1Gdy/Bdnf+
Genetic Background: involves: 129P2/OlaHsd
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| MP:0004428 | abnormal type I vestibular cell | "any structural abnormality in the flask-shaped sensory cells of the maculae and cristae of the vestibular labyrinth of the inner ear, which are normally enclosed in calyx endings of afferent neurons; afferent and efferent nerve fibers of the vestibular nerve synapse with them; from the apical end of each cell a bundle of stereocilia and a kinocilium extend into the otolithic membrane of the maculae or the cupula of the cristae " [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bdnftm1Jae/Bdnftm1Jae
Genetic Background: involves: 129S4/SvJae
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| MP:0004718 | abnormal vestibular nerve morphology | "any structural abnormality in the part of the vestibulocochlear nerve [CN VIII] peripheral to the vestibular root; it is composed of the central processes of bipolar neurons that have the terminals of their peripheral processes on the hair cells in the ampullae of the semicircular ducts and the maculae of the saccule and utricle, and cell bodies of the vestibular ganglion" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bdnftm1Jae/Bdnftm1Jae
Genetic Background: involves: 129S4/SvJae
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| MP:0004747 | abnormal cochlear OHC afferent innervation | "any changes in the morphology or number of afferent terminals and/or their synapses in the cochlear OHC region" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Nkx3-2tm1Bobh/Nkx3-2tm1Bobh
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Bdnftm1Tbn/Bdnftm1Tbn
Genetic Background: involves: 129S4/SvJae * NMRI
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| MP:0004811 | abnormal neuron physiology | "anomalous function of the cells of the nervous system that receive, conduct, and transmit impulses" [MESH:National Library of Medicine_Medical Subject Headings] |
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Allelic Composition: Bdnftm1Flee/Bdnftm1Flee
Genetic Background: B6.129-Bdnftm1Flee
Allelic Composition: Bdnftm1Flee/Bdnf+
Genetic Background: B6.129-Bdnftm1Flee
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| MP:0004859 | abnormal synaptic plasticity | "anomaly in the ability of a synapse to change its strength as a result of successive activations" [MESH:National Library of Medicine_Medical Subject Headings, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Btlatm1Dgra/Btlatm1Dgra,Tg(TcraTcrb)1100Mjb/?
Genetic Background: involves: C57BL/6
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| MP:0005191 | head tilt | "condition in which the portion of the body containing the brain and organs of sight, hearing, taste, and smell lists to the side" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Bdnftm1Jae/Bdnftm1Jae
Genetic Background: involves: 129S4/SvJae
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| MP:0005202 | lethargy | "mild impairment of consciousness resulting in reduced alertness and awareness; ultimately due to generalized brain dysfunction" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Bdnftm3Jae/Bdnftm3Jae,Mecp2tm1.1Jae/Y,Tg(Camk2a-cre)93Kln/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * CBA/J
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| MP:0005236 | abnormal olfactory nerve morphology | "anomalous structure of the first cranial nerve, which conveys the sense of smell" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Plectm4Gwi/Plectm4Gwi,Tg(KRT5-cre)1Tak/?
Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6
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| MP:0005322 | abnormal serotonin level | "anomalous concentration of biochemical messenger and regulator, found in the CNS, g.i. tract, and produced by platelets; it mediates neurotransmission, g.i. motility, hemostasis, and cardiovascular integrity " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Bdnftm1Par/Bdnf+
Genetic Background: B6.129S1-Bdnftm1Par
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| MP:0005331 | insulin resistance | "diminished effectiveness of insulin in lowering plasma glucose levels" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:84260, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Bdnftm3Jae/Bdnftm3Jae,Tg(Camk2a-cre)93Kln/0
Genetic Background: involves: 129S4/SvJae * CBA/J
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| MP:0005402 | abnormal action potential | "change in the electric response of a nerve or other excitable tissue to its stimulation" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Bdnftm3Jae/Bdnftm3Jae,Mecp2tm1.1Jae/Y,Tg(Camk2a-cre)93Kln/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * CBA/J
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| MP:0005500 | abnormal gustatory system morphology | "structural anomaly of the organs involved in taste " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Bdnftm1(Ntf3)Pern/Bdnftm1(Ntf3)Pern
Genetic Background: involves: 129P2/OlaHsd
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| MP:0005559 | increased circulating glucose level | "greater than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, RGD:Rat Genome Database submission] |
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Allelic Composition: Bdnftm3Jae/Bdnftm3Jae,Tg(Camk2a-cre)93Kln/0
Genetic Background: involves: 129S4/SvJae * CBA/J
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| MP:0005574 | decreased breathing frequency | "fewer than the normal number of breaths in a given period of time" [RGD:Rat Genome Database submission] |
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Allelic Composition: Bdnftm1Lfr/Bdnftm1Lfr
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0005655 | increased aggression | "when compared to controls, subjects exhibit greater than the normal level of domineering, assaultive posture and/or hostile physical action" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator] |
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Allelic Composition: Bdnftm1Krj/Bdnftm1Lfr,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129S2/SvPas * C57BL/6J
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| MP:0005669 | increased circulating leptin level | "greater than the normal blood concentration of the peptide hormone secreted by white adipocytes and believed to regulate food intake and energy balance" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, J:34751] |
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Allelic Composition: Bdnftm3Jae/Bdnftm3Jae,Tg(Camk2a-cre)93Kln/0
Genetic Background: involves: 129S4/SvJae * CBA/J
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| MP:0006254 | thin cerebral cortex | "decreased depth of the mantle covering the surface of the cerebral hemispheres" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:84683] |
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Allelic Composition: Bdnftm1Krj/Bdnftm1Lfr,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129S2/SvPas * C57BL/6J
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| MP:0006257 | abnormal fungiform papillae | "malformation, absence, or atypical size or shape of the mushroom-shaped papillae, which have a single tase bud at the tip, located mostly on the dorsal anterior portion of the tongue
" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:55127] |
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Allelic Composition: Bdnftm1Jae/Bdnftm1Jae
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Bdnftm1(Ntf3)Pern/Bdnftm1(Ntf3)Pern
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Bdnftm1Lfr/Bdnftm1Lfr
Genetic Background: involves: 129S2/SvPas
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| MP:0006258 | abnormal circumvallate papillae | "malformation, absence, or atypical size or shape of the large papillae, which have multiple taste buds in the trough surrounding the papillae, located near the base and on the dorsal side of the tongue" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:55127] |
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Allelic Composition: Bdnftm1Lfr/Bdnftm1Lfr
Genetic Background: involves: 129S2/SvPas
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| MP:0006260 | abnormal gustatory papillae taste buds | "malformation, absence, or atypical size or shape of the taste buds located on the gustatory papillae, which includes the fungiform, foliate, and circumvallate papillae" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:55127] |
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Allelic Composition: Bdnftm1Jae/Bdnftm1Jae
Genetic Background: B6.129S4-Bdnftm1Jae
Allelic Composition: Bdnftm1Lfr/Bdnftm1Lfr
Genetic Background: involves: 129S2/SvPas
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| MP:0008143 | abnormal dendrite morphology | "any structural anomaly of the highly branched tree-like process of a neuron that serves as a receptive field and conducts impulses toward the cell body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bdnftm1Flee/Bdnftm1Flee
Genetic Background: B6.129-Bdnftm1Flee
Allelic Composition: Bdnftm1Flee/Bdnf+
Genetic Background: B6.129-Bdnftm1Flee
Allelic Composition: Bdnftm1Yab/Bdnftm1Yab,Mapttm1(cre)Nagy/Mapt+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Allelic Composition: Bdnftm1Krj/Bdnftm1Krj
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0008265 | abnormal hippocampus CA2 region morphology | |
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Allelic Composition: Bdnftm3Jae/Bdnftm3Jae,Tg(Camk2a-cre)93Kln/0
Genetic Background: involves: 129S4/SvJae * CBA/J
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| MP:0008462 | abnormal medium spiny neuron morphology | "any structural anomaly of the inhibitory projection neurons located in the striatum that integrate glutamatergic signals arising from the cerebral cortex and thalamus" [PMID:15504319] |
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Allelic Composition: Bdnftm1Krj/Bdnftm1Lfr,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129S2/SvPas * C57BL/6J
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| MP:0008947 | increased neuron number | "greater than normal numbers of the cells of the nervous system that receive, conduct, and transmit impulses" [MESH:A08.663] |
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Allelic Composition: Bdnftm1Jae/Bdnftm1Jae
Genetic Background: involves: 129S4/SvJae * BALB/c
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| MP:0008960 | abnormal axon pruning | "defects in the developmental elimination of axons that fail to participate in an active neuronal circuit by retraction, degeneration, shedding or other mechanism" [MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"] |
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Allelic Composition: Cebpatm1Gonz/Cebpatm1Gonz,Tg(SFTPC-rtTA)5Jaw/0,Tg(tetO-cre)1Jaw/0
Genetic Background: involves: 129 * 129X1/SvJ * C57BL/6 * FVB/N
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| MP:0009456 | impaired cued conditioning behavior | "decrease in the ability of an animal to learn and remember an association between an aversive experience (the unconditioned stimulus (US), usually a shock) and a neutral stimulus (the conditioned stimulus (CS), usually an auditory cue or light flash)" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Lgr6tm2.1(cre/ERT2)Cle/Lgr6tm2.1(cre/ERT2)Cle
Genetic Background: Not Specified
Allelic Composition: Bdnftm3Jae/Bdnftm3Jae
Genetic Background: involves: 129S4/SvJae
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| MP:0009747 | impaired behavioral response to xenobiotic | "decreased sensitivity to a foreign compound capable of inducing the appearance of behavioral response, such as consumption preference, induced hyperactivity or stereotypic behavior, or increased dosage threshold for the appearance of the behavioral response" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bdnftm3Jae/Bdnftm3Jae,Tg(Eno2tTA)5030Nes/0,Tg(tetO-cre)1Jaw/0
Genetic Background: involves: 129/Sv * C57BL/6 * ICR * SJL
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| MP:0009907 | decreased tongue size | "reduced size of the mobile mass of muscular tissue and surrounding epithelial tissue occupying the cavity of the mouth and forming part of the floor" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Bdnftm1Lfr/Bdnftm1Lfr
Genetic Background: involves: 129S2/SvPas
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| MP:0009936 | abnormal dendritic spine morphology | "any structural anomaly of the small membranous protrusion from the dendrite of a neuron that is involved in synaptic transmission; it typically receives input from a single synapse of an axon" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bdnftm1Krj/Bdnftm1Krj
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0009937 | abnormal neuron differentiation | "abnormal growth or development of the cells of the nervous system that receive, conduct, and transmit impulses" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bdnftm1Lfr/Bdnftm1Lfr
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Bdnftm1Par/Bdnftm1Par,Ntf5tm1Par/Ntf5tm1Par
Genetic Background: involves: 129S1/Sv * C57BL/6
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| MP:0011085 | complete postnatal lethality | "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: Bdnftm1Lfr/Bdnftm1Lfr
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Bdnftm1Par/Bdnftm1Par
Genetic Background: involves: 129S1/Sv
Allelic Composition: Bdnftm1Tbn/Bdnftm1Tbn
Genetic Background: involves: 129S4/SvJae * NMRI
Allelic Composition: Bdnftm1Gdy/Bdnftm1Gdy,Ntf5tm1Gdy/Ntf5tm1Gdy
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Bdnftm1Jae/Bdnftm1Jae,Ntf5tm1Jae/Ntf5tm1Jae
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Bdnftm1Yab/Bdnftm1Yab,Mapttm1(cre)Nagy/Mapt+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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| MP:0011086 | partial postnatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: Nkx3-2tm1Bobh/Nkx3-2tm1Bobh
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Bdnftm1Jae/Bdnftm1Jae
Genetic Background: involves: 129S4/SvJae
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| MP:0011087 | complete neonatal lethality | "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith] |
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Allelic Composition: Bdnftm1Par/Bdnftm1Par,Ntf3tm1Par/Ntf3tm1Par
Genetic Background: involves: 129S1/Sv
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| MP:0012468 | decreased striatum area | "reduced size of a large cluster of dopaminergic nerve cells, consisting of the caudate nucleus and the putamen, that controls movement, balance, and walking" [ISBN:0838580343, MGI:csmith] |
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Allelic Composition: Bdnftm1Krj/Bdnftm1Lfr,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129S2/SvPas * C57BL/6J
Allelic Composition: Bdnftm1Yab/Bdnftm1Yab,Mapttm1(cre)Nagy/Mapt+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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| MP:0013219 | abnormal substantia nigra pars compacta morphology | "any structural anomaly of the posterior (dorsal) part of grey matter of the substantia nigra which contains large, polygonal, and densely packed dopamine-producing cells; pars compacta neurons are pigmented in many species" [MGI:anna] |
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Allelic Composition: Bdnftm1Krj/Bdnftm1Lfr,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S2/SvPas * C57BL/6 * CBA
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| MP:0013795 | abnormal colon goblet cell morphology | "any structural anomaly of the glandular simple columnar epithelial cell found in the mucosal lining of the colon, whose primary function is to secrete gel-forming mucins, the major components of mucus" [MGI:Anna, PMID:25872481] |
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Allelic Composition: Bdnftm1Tbn/Bdnftm1Tbn
Genetic Background: involves: 129S4/SvJae * NMRI
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| MP:0020083 | decreased hippocampus volume | "decrease from the average range of the hippocampus volume compared to normal" [GOC:NV] |
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Allelic Composition: Bdnftm1Flee/Bdnftm1Flee
Genetic Background: B6.129-Bdnftm1Flee
Allelic Composition: Bdnftm1Flee/Bdnf+
Genetic Background: B6.129-Bdnftm1Flee
Allelic Composition: Bdnftm1Par/Bdnf+
Genetic Background: involves: 129S1/Sv
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