ENSDARG00000043716


Danio rerio

Features
Gene ID: ENSDARG00000043716
  
Biological name :cldn5a
  
Synonyms : claudin 5a / cldn5a
  
Possible biological names infered from orthology : claudin 5 / CLDN5 / O00501 / O54942
  
Species: Danio rerio
  
Chr. number: 8
Strand: 1
Band:
Gene start: 4697764
Gene end: 4699320
  
Corresponding Affymetrix probe sets: Dr.17890.1.S1_at (Zebrafish Array)   Dr.17890.3.A1_at (Zebrafish Array)   NM_213274_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000064196
NCBI entrez gene - 406559     See in Manteia.
RefSeq - NM_213274
RefSeq Peptide - NP_998439
swissprot - Q6NUZ6
ZFIN ID - ZDB-GENE-040426-2442
Ensembl - ENSDARG00000043716
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CLDN5ENSGALG00000001621Gallus gallus
 CLDN5ENSG00000184113Homo sapiens
 Cldn5ENSMUSG00000041378Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cldn5b / claudin 5b / CLDN5* / O00501* / O54942* / claudin 5*ENSDARG0000001405973
cldnb / claudin b / CLDN4* / O14493* / O35054* / claudin 4*ENSDARG0000000954459
cldnc / claudin c / CLDN4* / O14493* / O35054* / claudin 4*ENSDARG0000001595557
cldnd / Q9YH91 / claudin d / CLDN4* / O14493* / O35054* / claudin 4*ENSDARG0000000658056
cldne / claudin e / CLDN4* / O14493* / O35054* / claudin 4*ENSDARG0000004312854
zgc:112437 / CLDN4 (1 of many) / CLDN4* / O14493* / O35054* / claudin 4*ENSDARG0000000921553
cldnh / claudin h / CLDN4* / O14493* / O35054* / claudin 4*ENSDARG0000006950353
cldna / claudin a / CLDN4* / O14493* / O35054* / claudin 4*ENSDARG0000006988852
cldng / Q9YH90 / claudin g / CLDN4* / O14493* / O35054* / claudin 4*ENSDARG0000000370150
cldnk / claudin kENSDARG0000004235746
cldnj / claudin jENSDARG0000005888045
cldnf / claudin f / CLDN4* / O14493* / O35054* / claudin 4*ENSDARG0000004313344
zgc:110333 / CLDN8 (1 of many) / CLDN8* / P56748* / claudin 8*ENSDARG0000004062840
cldn2 / claudin 2 / O88552* / P57739*ENSDARG0000004438740
Q9YH92 / cldn7b / claudin 7b / CLDN7* / Q9Z261* / O95471* / claudin 7*ENSDARG0000001404740
Q6DHP1 / cldn7a / claudin 7a / CLDN7* / Q9Z261* / O95471* / claudin 7*ENSDARG0000003637639
cldn17 / claudin 17 / CLDN8* / P56748* / claudin 8*ENSDARG0000009995038
zgc:136892 / CLDN4 (1 of many) / CLDN4* / O14493* / O35054* / claudin 4*ENSDARG0000006950538
cldn19 / claudin 19 / Q8N6F1* / Q9ET38*ENSDARG0000004456936
cldn1 / claudin 1 / O95832*ENSDARG0000004004534


Protein motifs (from Interpro)
Interpro ID Name
 IPR004031  PMP-22/EMP/MP20/Claudin superfamily
 IPR006187  Claudin
 IPR017974  Claudin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0061028 establishment of endothelial barrier IMP
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005923 bicellular tight junction IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0043296 apical junction complex IMP
 molecular_functionGO:0005198 structural molecule activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000001 Kupffer s vesicle Kupffers vesicle absent , abnormal
Kupffers vesicle anatomical region spatial pattern , abnormal
Kupffers vesicle structure, cavities , abnormal
Kupffers vesicle decreased area , abnormal
Kupffers vesicle uninflated , abnormal
Kupffers vesicle cilium decreased amount , abnormal
Kupffers vesicle cell decreased amount , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000110 fourth ventricle fourth ventricle decreased volume , abnormal
Show

 ZFA:0000151 pronephros pronephros cystic , abnormal
Show

 ZFA:0000159 tectal ventricle tectal ventricle decreased volume , abnormal
Show

 ZFA:0000360 heart tube heart tube mislocalised , abnormal
Show

 ZFA:0001261 ventricular system ventricular system lumenized , abnormal
Show

 ZFA:0005046 hyaloid vessel hyaloid vessel broken , abnormal
Show

 ZFA:0009306 neuroepithelial cell neuroepithelial cell bicellular tight junction increased permeability , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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