ENSG00000143641


Homo sapiens

Features
Gene ID: ENSG00000143641
  
Biological name :GALNT2
  
Synonyms : GALNT2 / polypeptide N-acetylgalactosaminyltransferase 2 / Q10471
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q42.13
Gene start: 230057990
Gene end: 230282124
  
Corresponding Affymetrix probe sets: 217787_s_at (Human Genome U133 Plus 2.0 Array)   217788_s_at (Human Genome U133 Plus 2.0 Array)   223991_s_at (Human Genome U133 Plus 2.0 Array)   239930_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000355632
NCBI entrez gene - 2590     See in Manteia.
OMIM - 602274
RefSeq - XM_017000966
RefSeq - NM_001291866
RefSeq - NM_004481
RefSeq - XM_017000963
RefSeq - XM_017000964
RefSeq - XM_017000965
RefSeq Peptide - NP_001278795
RefSeq Peptide - NP_004472
swissprot - A0A1L7NY50
swissprot - Q10471
Ensembl - ENSG00000143641
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 galnt2ENSDARG00000003829Danio rerio
 GALNT2ENSGALG00000011106Gallus gallus
 Galnt2ENSMUSG00000089704Mus musculus
 Q6PB93ENSMUSG00000092329Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8N428 / GALNT16 / polypeptide N-acetylgalactosaminyltransferase 16ENSG0000010062650
Q96FL9 / GALNT14 / polypeptide N-acetylgalactosaminyltransferase 14ENSG0000015808944
Q8NCW6 / GALNT11 / polypeptide N-acetylgalactosaminyltransferase 11ENSG0000017823440
GALNT1 / Q10472 / polypeptide N-acetylgalactosaminyltransferase 1ENSG0000014142940
Q8IUC8 / GALNT13 / polypeptide N-acetylgalactosaminyltransferase 13ENSG0000014427839
GALNT6 / Q8NCL4 / polypeptide N-acetylgalactosaminyltransferase 6ENSG0000013962938
Q8IXK2 / GALNT12 / polypeptide N-acetylgalactosaminyltransferase 12ENSG0000011951438
GALNT4 / Q8N4A0 / polypeptide N-acetylgalactosaminyltransferase 4ENSG0000025759437
POC1B-GALNT4 / POC1B-GALNT4 readthroughENSG0000025907537
GALNT5 / Q7Z7M9 / polypeptide N-acetylgalactosaminyltransferase 5ENSG0000013654236
GALNT3 / Q14435 / polypeptide N-acetylgalactosaminyltransferase 3ENSG0000011533936
Q7Z4T8 / GALNTL5 / polypeptide N-acetylgalactosaminyltransferase like 5ENSG0000010664829


Protein motifs (from Interpro)
Interpro ID Name
 IPR000772  Ricin B, lectin domain
 IPR001173  Glycosyltransferase 2-like
 IPR029044  Nucleotide-diphospho-sugar transferases
 IPR035992  Ricin B-like lectins


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002378 immunoglobulin biosynthetic process IDA
 biological_processGO:0006486 protein glycosylation IEA
 biological_processGO:0006493 protein O-linked glycosylation IDA
 biological_processGO:0016266 O-glycan processing IDA
 biological_processGO:0018242 protein O-linked glycosylation via serine IDA
 biological_processGO:0018243 protein O-linked glycosylation via threonine IDA
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005795 Golgi stack IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030173 integral component of Golgi membrane NAS
 cellular_componentGO:0032580 Golgi cisterna membrane IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004653 polypeptide N-acetylgalactosaminyltransferase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0030145 manganese ion binding IDA
 molecular_functionGO:0030246 carbohydrate binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
COPI-independent Golgi-to-ER retrograde traffic
O-linked glycosylation of mucins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000104671 DCTN6 / O00399 / dynactin subunit 6  / reaction / complex
 ENSG00000131966 ACTR10 / Q9NZ32 / actin related protein 10 homolog  / reaction / complex
 ENSG00000088986 DYNLL1 / P63167 / dynein light chain LC8-type 1  / reaction / complex
 ENSG00000137100 DCTN3 / O75935 / dynactin subunit 3  / complex / reaction
 ENSG00000135720 O43237 / DYNC1LI2 / dynein cytoplasmic 1 light intermediate chain 2  / reaction / complex
 ENSG00000077549 CAPZB / P47756 / capping actin protein of muscle Z-line beta subunit  / reaction / complex
 ENSG00000116489 CAPZA1 / P52907 / capping actin protein of muscle Z-line alpha subunit 1  / complex / reaction
 ENSG00000144635 Q9Y6G9 / DYNC1LI1 / dynein cytoplasmic 1 light intermediate chain 1  / reaction / complex
 ENSG00000166847 DCTN5 / Q9BTE1 / dynactin subunit 5  / complex / reaction
 ENSG00000177938 CAPZA3 / Q96KX2 / capping actin protein of muscle Z-line alpha subunit 3  / reaction / complex
 ENSG00000077380 Q13409 / DYNC1I2 / dynein cytoplasmic 1 intermediate chain 2  / complex / reaction
 ENSG00000158560 O14576 / DYNC1I1 / dynein cytoplasmic 1 intermediate chain 1  / complex / reaction
 ENSG00000204843 DCTN1 / Q14203 / dynactin subunit 1  / reaction / complex
 ENSG00000197102 Q14204 / DYNC1H1 / dynein cytoplasmic 1 heavy chain 1  / reaction / complex
 ENSG00000198898 CAPZA2 / P47755 / capping actin protein of muscle Z-line alpha subunit 2  / complex / reaction
 ENSG00000175582 RAB6A / P20340 / RAB6A, member RAS oncogene family  / complex / reaction
 ENSG00000151746 BICD1 / Q96G01 / BICD cargo adaptor 1  / reaction / complex
 ENSG00000138107 ACTR1A / P61163 / ARP1 actin related protein 1 homolog A  / reaction / complex
 ENSG00000007168 P43034 / PAFAH1B1 / platelet activating factor acetylhydrolase 1b regulatory subunit 1  / reaction
 ENSG00000132912 DCTN4 / Q9UJW0 / dynactin subunit 4  / complex / reaction
 ENSG00000175203 DCTN2 / Q13561 / dynactin subunit 2  / reaction / complex
 ENSG00000264364 DYNLL2 / Q96FJ2 / dynein light chain LC8-type 2  / reaction / complex






 

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