ENSG00000151746


Homo sapiens

Features
Gene ID: ENSG00000151746
  
Biological name :BICD1
  
Synonyms : BICD1 / BICD cargo adaptor 1 / Q96G01
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: p11.21
Gene start: 32106835
Gene end: 32383633
  
Corresponding Affymetrix probe sets: 1554020_at (Human Genome U133 Plus 2.0 Array)   1556051_a_at (Human Genome U133 Plus 2.0 Array)   204741_at (Human Genome U133 Plus 2.0 Array)   214806_at (Human Genome U133 Plus 2.0 Array)   231964_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000448933
Ensembl peptide - ENSP00000447663
Ensembl peptide - ENSP00000475837
Ensembl peptide - ENSP00000481877
Ensembl peptide - ENSP00000281474
Ensembl peptide - ENSP00000379107
Ensembl peptide - ENSP00000446793
Ensembl peptide - ENSP00000447238
NCBI entrez gene - 636     See in Manteia.
OMIM - 602204
RefSeq - XM_017019797
RefSeq - NM_001354187
RefSeq - NM_001714
RefSeq - XM_005253465
RefSeq - XM_006719134
RefSeq - XM_011520812
RefSeq - XM_011520813
RefSeq - XM_011520814
RefSeq - XM_011520815
RefSeq - XM_011520816
RefSeq - NM_001003398
RefSeq Peptide - NP_001003398
RefSeq Peptide - NP_001341116
RefSeq Peptide - NP_001705
swissprot - Q96G01
swissprot - A8MVZ6
swissprot - A0A087WYJ7
swissprot - U3KQF7
swissprot - F8VZX7
swissprot - F8W056
Ensembl - ENSG00000151746
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 bicd1aENSDARG00000079496Danio rerio
 CABZ01085700.1ENSDARG00000098551Danio rerio
 ENSGALG00000032522Gallus gallus
 Bicd1ENSMUSG00000003452Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BICD2 / Q8TD16 / BICD cargo adaptor 2ENSG0000018596354


Protein motifs (from Interpro)
Interpro ID Name
 IPR018477  Bicaudal-D protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006396 RNA processing TAS
 biological_processGO:0008298 intracellular mRNA localization NAS
 biological_processGO:0009653 anatomical structure morphogenesis TAS
 biological_processGO:0016032 viral process IMP
 biological_processGO:0033365 protein localization to organelle IDA
 biological_processGO:0034063 stress granule assembly IEA
 biological_processGO:0048260 positive regulation of receptor-mediated endocytosis IMP
 biological_processGO:0070507 regulation of microtubule cytoskeleton organization IGI
 biological_processGO:0072385 minus-end-directed organelle transport along microtubule IMP
 biological_processGO:0072393 microtubule anchoring at microtubule organizing center IEA
 biological_processGO:1900275 negative regulation of phospholipase C activity IEA
 biological_processGO:1900276 regulation of proteinase activated receptor activity IEA
 biological_processGO:1900737 negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway IEA
 biological_processGO:1904781 positive regulation of protein localization to centrosome IGI
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005802 trans-Golgi network IDA
 cellular_componentGO:0005813 centrosome IMP
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005856 cytoskeleton NAS
 cellular_componentGO:0005881 cytoplasmic microtubule IDA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0031410 cytoplasmic vesicle IDA
 cellular_componentGO:0045298 tubulin complex TAS
 cellular_componentGO:0048471 perinuclear region of cytoplasm IMP
 cellular_componentGO:0072517 host cell viral assembly compartment IDA
 molecular_functionGO:0005200 structural constituent of cytoskeleton TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008093 cytoskeletal adaptor activity IEA
 molecular_functionGO:0017137 Rab GTPase binding IPI
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0031871 proteinase activated receptor binding ISS
 molecular_functionGO:0034452 dynactin binding IPI
 molecular_functionGO:0045505 dynein intermediate chain binding IDA
 molecular_functionGO:0070840 dynein complex binding IEA


Pathways (from Reactome)
Pathway description
COPI-independent Golgi-to-ER retrograde traffic


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000104671 DCTN6 / O00399 / dynactin subunit 6  / complex / reaction
 ENSG00000131966 ACTR10 / Q9NZ32 / actin related protein 10 homolog  / reaction / complex
 ENSG00000088986 DYNLL1 / P63167 / dynein light chain LC8-type 1  / complex / reaction
 ENSG00000137100 DCTN3 / O75935 / dynactin subunit 3  / reaction / complex
 ENSG00000135720 O43237 / DYNC1LI2 / dynein cytoplasmic 1 light intermediate chain 2  / complex / reaction
 ENSG00000077549 CAPZB / P47756 / capping actin protein of muscle Z-line beta subunit  / complex / reaction
 ENSG00000116489 CAPZA1 / P52907 / capping actin protein of muscle Z-line alpha subunit 1  / complex / reaction
 ENSG00000144635 Q9Y6G9 / DYNC1LI1 / dynein cytoplasmic 1 light intermediate chain 1  / complex / reaction
 ENSG00000151746 BICD1 / Q96G01 / BICD cargo adaptor 1  / complex
 ENSG00000175582 RAB6A / P20340 / RAB6A, member RAS oncogene family  / complex / reaction
 ENSG00000166847 DCTN5 / Q9BTE1 / dynactin subunit 5  / complex / reaction
 ENSG00000141429 GALNT1 / Q10472 / polypeptide N-acetylgalactosaminyltransferase 1  / reaction / complex
 ENSG00000177938 CAPZA3 / Q96KX2 / capping actin protein of muscle Z-line alpha subunit 3  / reaction / complex
 ENSG00000077380 Q13409 / DYNC1I2 / dynein cytoplasmic 1 intermediate chain 2  / reaction / complex
 ENSG00000158560 O14576 / DYNC1I1 / dynein cytoplasmic 1 intermediate chain 1  / complex / reaction
 ENSG00000204843 DCTN1 / Q14203 / dynactin subunit 1  / complex / reaction
 ENSG00000197102 Q14204 / DYNC1H1 / dynein cytoplasmic 1 heavy chain 1  / complex / reaction
 ENSG00000198898 CAPZA2 / P47755 / capping actin protein of muscle Z-line alpha subunit 2  / complex / reaction
 ENSG00000143641 GALNT2 / Q10471 / polypeptide N-acetylgalactosaminyltransferase 2  / reaction / complex
 ENSG00000138107 ACTR1A / P61163 / ARP1 actin related protein 1 homolog A  / reaction / complex
 ENSG00000007168 P43034 / PAFAH1B1 / platelet activating factor acetylhydrolase 1b regulatory subunit 1  / reaction
 ENSG00000132912 DCTN4 / Q9UJW0 / dynactin subunit 4  / complex / reaction
 ENSG00000175203 DCTN2 / Q13561 / dynactin subunit 2  / complex / reaction
 ENSG00000264364 DYNLL2 / Q96FJ2 / dynein light chain LC8-type 2  / reaction / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr