ENSG00000158748


Homo sapiens

Features
Gene ID: ENSG00000158748
  
Biological name :HTR6
  
Synonyms : 5-hydroxytryptamine receptor 6 / HTR6 / P50406
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p36.13
Gene start: 19665287
Gene end: 19679562
  
Corresponding Affymetrix probe sets: 1552857_a_at (Human Genome U133 Plus 2.0 Array)   206944_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000289753
NCBI entrez gene - 3362     See in Manteia.
OMIM - 601109
RefSeq - NM_000871
RefSeq Peptide - NP_000862
swissprot - P50406
Ensembl - ENSG00000158748
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 htr6ENSDARG00000016095Danio rerio
 HTR6ENSGALG00000004066Gallus gallus
 Htr6ENSMUSG00000028747Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ADRB1 / P08588 / adrenoceptor beta 1ENSG0000004359130
DRD5 / P21918 / dopamine receptor D5ENSG0000016967629
DRD1 / P21728 / dopamine receptor D1ENSG0000018484528
ADRB3 / P13945 / adrenoceptor beta 3ENSG0000018877827
HRH2 / P25021 / histamine receptor H2ENSG0000011374925
HTR2B / P41595 / 5-hydroxytryptamine receptor 2BENSG0000013591424
DRD4 / P21917 / dopamine receptor D4ENSG0000006969624
ADRB2 / P07550 / adrenoceptor beta 2ENSG0000016925224
DRD2 / P14416 / dopamine receptor D2ENSG0000014929524
HTR2C / P28335 / 5-hydroxytryptamine receptor 2CENSG0000014724623
DRD3 / P35462 / dopamine receptor D3ENSG0000015157723
HTR2A / P28223 / 5-hydroxytryptamine receptor 2AENSG0000010246822


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR002232  5-Hydroxytryptamine 6 receptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger TAS
 biological_processGO:0007268 chemical synaptic transmission TAS
 biological_processGO:0021795 cerebral cortex cell migration IEA
 biological_processGO:0032008 positive regulation of TOR signaling IEA
 biological_processGO:0098664 G-protein coupled serotonin receptor signaling pathway IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004969 histamine receptor activity TAS
 molecular_functionGO:0004993 G-protein coupled serotonin receptor activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030594 neurotransmitter receptor activity IBA


Pathways (from Reactome)
Pathway description
Serotonin receptors
G alpha (s) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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